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E7FFA5

- E7FFA5_DANRE

UniProt

E7FFA5 - E7FFA5_DANRE

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Protein
Submitted name: Uncharacterized protein
Gene
ace
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotation
Binds 2 zinc ions per subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. metallopeptidase activity Source: InterPro
  2. peptidyl-dipeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

CarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

ReactomeiREACT_215763. Metabolism of Angiotensinogen to Angiotensins.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:aceImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 12

Organism-specific databases

ZFINiZDB-GENE-030131-1826. ace.

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

GlycoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiE7FFA5.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00520000055576.
KOiK01283.
OMAiMEQLFTV.
OrthoDBiEOG76HQ13.
PhylomeDBiE7FFA5.
TreeFamiTF312861.

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 2 hits.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

E7FFA5-1 [UniParc]FASTAAdd to Basket

« Hide

MNRGKRESRT PIGKQEHPAV NVSRRLLRKL LSQHSASQLR SIMLRAVVLL     50
TLISWSAALK PEWMPGDYPP TEQGAERFVS DYNSTAEEVL YLSTEASWNY 100
NTNLTDHNSQ LQIEASLEEQ AFTEAWGHKA KATFSESLMD TFTNPDLKKI 150
IKKINVLEAA NLAITDRELY NTILSQMDSI YSTAKVCPSP EECWSLEPEL 200
QEIMATSRSY KRLLYAWEGW HNSSGVPLKS LYAEFVKISN KASQMDGFKD 250
TGEYWRSWYE SPTFKQDLEN LFKQLEPLYQ NLHAFVRRKL YDYYGPKYIN 300
LKGPIPAHLL GNMWSQTWNN IYNMMIPFPN RPNVDVTNTM IAKGYNATHM 350
FRVAEEFFTS LGLLEMPPEF WDKSMLEKPT DGREVVCHAS AWDFYNRKDF 400
RIKQCTTVTM EQLFTVHHEM GHVEYYLQYK DQPVSFRRGA NPGFHEAIGD 450
VLSLSVSTPK HLHSIDLLDQ LTDDAESDIN YLLKMALEKI AFLPFGYLID 500
QWRWSVFSGE TPPDRYNADW WYLRTKYQGI CPPTRRTEEH FDAGGKYHIP 550
GNTPYIRYFV SFILQFQFHE KLCKEAGHTG PLHKCDIYKS REAGAVLEKV 600
LKAGSSEPWT QVLQEALGTD KMDATPLMSY FLPVTTWLRE QNEKTGETLG 650
WPDFNWVPPI PEGYPEDIGK ITDEMQAKQF LDEYNSTAEE VWNAYTESSW 700
TYNTDITEAH KDNMLQKNLE MANHTKIYGL EARKYDTSDF QDESVKRILS 750
KLSDLERAAL SAEDLVEYNN LLASMETLYS VATVCKDKSN CLPLDPDLNK 800
IMAESRDYDE LLFAWQGWRN ASGREIRDSY KRYVELANSA AKSNGHTDNG 850
AFWRSLYETP TFEQDLEALW KDLEPLYLSV HAYVRRALYK KYGPERINLK 900
GPIPAHLLGN MWAQTWSGIM DLVNPYPDAT QVDATPAMIA QGWTPKRMFE 950
ESDRFFTSLG LLPMPPEFWN KSMLEKPTDG REVVCHASAW DFYNRKDFRI 1000
KQCTVVTMDD LITVHHEMGH VQYFLQYKDQ PISFRDGANP GFHEAIGDVL 1050
ALSVATPKHL QSIGLLDKVE DNAESTINFL MSIALDKIAF LPFGYLMDQW 1100
RWKVFDGRIS SSEYNKEWWN LRMKYQGLCP PVPRTEKDFD PGAKFHIPAN 1150
VPYIRYFVSF VIQFQFHKGL CDAAGHKGPL HNCDIYQSKE AGKLLSDVMK 1200
MGFSKPWPEA MKIITGQPKM SVQPLMEYFK PLIEWLEKEN EKNGDVLGWP 1250
EYDWTPYKLS TVVEESPKSV NFLGLSVDAA GAAAGQWILL VLSIVFLLAV 1300
VFLAYRYSKT KRLQNKSMSQ MELK 1324
Length:1,324
Mass (Da):152,783
Last modified:March 8, 2011 - v1
Checksum:iD19F8E94B5171322
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT998555 Genomic DNA. No translation available.
CU459092 Genomic DNA. No translation available.
RefSeqiXP_694336.5. XM_689244.6.
UniGeneiDr.4864.

Genome annotation databases

EnsembliENSDART00000114637; ENSDARP00000099084; ENSDARG00000079166.
GeneIDi565980.
KEGGidre:565980.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT998555 Genomic DNA. No translation available.
CU459092 Genomic DNA. No translation available.
RefSeqi XP_694336.5. XM_689244.6.
UniGenei Dr.4864.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000114637 ; ENSDARP00000099084 ; ENSDARG00000079166 .
GeneIDi 565980.
KEGGi dre:565980.

Organism-specific databases

CTDi 1636.
ZFINi ZDB-GENE-030131-1826. ace.

Phylogenomic databases

GeneTreei ENSGT00520000055576.
KOi K01283.
OMAi MEQLFTV.
OrthoDBi EOG76HQ13.
PhylomeDBi E7FFA5.
TreeFami TF312861.

Enzyme and pathway databases

Reactomei REACT_215763. Metabolism of Angiotensinogen to Angiotensins.

Miscellaneous databases

NextBioi 20887957.

Gene expression databases

Bgeei E7FFA5.

Family and domain databases

InterProi IPR001548. Peptidase_M2.
[Graphical view ]
PANTHERi PTHR10514. PTHR10514. 1 hit.
Pfami PF01401. Peptidase_M2. 2 hits.
[Graphical view ]
PRINTSi PR00791. PEPDIPTASEA.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  2. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiE7FFA5_DANRE
AccessioniPrimary (citable) accession number: E7FFA5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: September 3, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi