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Protein
Submitted name:

Rho GTPase-activating protein 27

Gene

arhgap27

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGTPase activationSAAS annotation

Enzyme and pathway databases

ReactomeiR-DRE-194840 Rho GTPase cycle

Names & Taxonomyi

Protein namesi
Submitted name:
Rho GTPase-activating protein 27Imported
Gene namesi
Name:arhgap27Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 12

Organism-specific databases

ZFINiZDB-GENE-030131-3922 arhgap27

PTM / Processingi

Proteomic databases

PaxDbiE7FCI7

Expressioni

Gene expression databases

BgeeiENSDARG00000104255

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000110192

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 80SH3InterPro annotationAdd BLAST64
Domaini316 – 345WWInterPro annotationAdd BLAST30
Domaini378 – 412WWInterPro annotationAdd BLAST35
Domaini490 – 523WWInterPro annotationAdd BLAST34
Domaini583 – 697PHInterPro annotationAdd BLAST115
Domaini781 – 968Rho-GAPInterPro annotationAdd BLAST188

Keywords - Domaini

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00890000139322
OMAiCHLHNLC
OrthoDBiEOG091G164H

Family and domain databases

CDDicd00201 WW, 2 hits
Gene3Di1.10.555.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR001202 WW_dom
IPR036020 WW_dom_sf
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00620 RhoGAP, 1 hit
PF00018 SH3_1, 1 hit
PF00397 WW, 2 hits
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00324 RhoGAP, 1 hit
SM00456 WW, 3 hits
SUPFAMiSSF48350 SSF48350, 1 hit
SSF50044 SSF50044, 1 hit
SSF51045 SSF51045, 2 hits
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS50238 RHOGAP, 1 hit
PS50002 SH3, 1 hit
PS01159 WW_DOMAIN_1, 3 hits
PS50020 WW_DOMAIN_2, 3 hits

Sequencei

Sequence statusi: Complete.

E7FCI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPDPLFAPQ HVWATMSLSQ QVLVNYEYTY TARDGRNVSI KPNEHYILVN
60 70 80 90 100
KTNEEWWHVQ KDAADKPFYI PAKYVTELPP ETSQTPLDPP EEFSGYESLQ
110 120 130 140 150
FGSQTADPAE VTLRVPDSIK RDTEKDGHRI STFIIPKEFF ELKGLDPDPI
160 170 180 190 200
KTEAEAGPPV SSNTSSPTNG ETAFIILPPP VYTVNTTQST ETDTRSVDDP
210 220 230 240 250
KDSVGRPRVD SSTIDEDIQM LNRAGWSEVL DVMGKEKNVY ESLDTVREPE
260 270 280 290 300
SPKDEADMTV NTTPVTPDAP MVEDDTAVYV NIPRKRQTTI NNSSPIASLL
310 320 330 340 350
QDFPEPPENF LLDSAGWQVH TDDQSGQEFY YQPSTGRSTW ENPLSSRSME
360 370 380 390 400
SPVGTEGGRS PPSFPQSPAC SPVAPAPRRW SSDWEKVLDE STGRHYFFNT
410 420 430 440 450
VSGQSSWDPP EDVDSPGRLM FLDDCPPPLP EEDYPASPEL EEASPVSIPA
460 470 480 490 500
EYSLIHVKKV SIPRVSLDRS SPAGWSLDID SEGTWTFTSE YTQEQWIKSL
510 520 530 540 550
DDQGRTYYYL RDGSKSQWNL PEYSASPGQY GVGNGASGEQ DTVGSNWRHS
560 570 580 590 600
AGYPDDKNHS SYIQNTSDSE ASSSPDTPHN VSNLEKAGIL NKTKVSENGK
610 620 630 640 650
KVRKNWGHSW TVLHGGKLTF HKDPKSTPAG ASSKTNQILP EFTVDLKGAT
660 670 680 690 700
INRAPKDKSS KKNVLELKTR TGAEYLIQYD TDSIIQDWHK VILDTIHQLN
710 720 730 740 750
GDQHHSEEED EVIDKSPTLD REERPFEKRT MSTATRQPST SSTSEAEQKK
760 770 780 790 800
VRTKLKKFLL KRPTLQSVKD KGYIRENVFG CHLHNLCSQE KTRVPSFVEK
810 820 830 840 850
CIRAVEKRGL EIDGLYRVSG NLAVIQKLRF KADHEDLDLE EGNWDIHVIT
860 870 880 890 900
GALKLFFREL QEPLFPYNLF NEFICAIKTP DYYSKISHMR NLVRSLPPPN
910 920 930 940 950
HDTMEALFSH LRRVIQHGNE NRMTVQNVAI VFGPTLLKPE EETASIATYM
960 970
VFQNQIVEFL LSEFESIFHM
Length:970
Mass (Da):109,372
Last modified:March 8, 2011 - v1
Checksum:iDF3F1D9DBBE0DEBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL929469 Genomic DNA No translation available.
BX323464 Genomic DNA No translation available.
CR354587 Genomic DNA No translation available.
RefSeqiXP_005156086.1, XM_005156029.3
UniGeneiDr.117128

Genome annotation databases

EnsembliENSDART00000161076; ENSDARP00000132429; ENSDARG00000104255
GeneIDi564211

Similar proteinsi

Entry informationi

Entry nameiE7FCI7_DANRE
AccessioniPrimary (citable) accession number: E7FCI7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: March 28, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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