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Protein
Submitted name:

Uncharacterized protein

Gene

map3k5

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-2559580. Oxidative Stress Induced Senescence.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:map3k5Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 20

Organism-specific databases

ZFINiZDB-GENE-030827-3. map3k5.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiE7F2L3.

Expressioni

Gene expression databases

BgeeiE7F2L3.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000046640.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini669 – 927259Protein kinaseInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili1236 – 126732Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains protein kinase domain.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4279. Eukaryota.
ENOG410XQGS. LUCA.
GeneTreeiENSGT00800000124036.
InParanoidiE7F2L3.
KOiK04426.
OMAiTELHCKK.
OrthoDBiEOG7WDN1P.
PhylomeDBiE7F2L3.
TreeFamiTF105115.

Family and domain databases

InterProiIPR025136. DUF4071.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR013761. SAM/pointed.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF13281. DUF4071. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E7F2L3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSDLEAISL SVPSLSQPLE MMMVMMGGSD GESSAGNNSS AGAFWQDPSN
60 70 80 90 100
CKSANPGLIS LPSDGVALLT PGKCKSRAVT VAYVRNSETS QPSSPENMAL
110 120 130 140 150
QCLKDACDIV GCKLDVVPFG KLDFGETSVL DHFYNADIAV VELTDAFRQP
160 170 180 190 200
SLFYHLGVRE SFCMVNNIIL YCDHNSDSLQ SLQDLICQKN MTCAANYTFI
210 220 230 240 250
PYMVTPQSKV YCCESSLMKG LSELMQPSFE ALLGPICMPL LDRLTQLLTG
260 270 280 290 300
CKSNTCQYFR ETVLNEIRKA RELYTGAELA AELRRIQQRL DNVECLSADV
310 320 330 340 350
VINLLLSYRD IQDYESIVKL VETLEKLPTF DPVAHPHIKF HYAFALNRRN
360 370 380 390 400
LPGDRQKALD IMLPLVNSDE QVASDIYCLV GRIYKDMFLD SHFTDTNSRD
410 420 430 440 450
QGIHWFRRGF ESEPTLHSGI NYAVLLLAAG HQFDSSFELR KVGVKLSSLL
460 470 480 490 500
GKKGSLDRLQ SYWDVGFFLG ASILACDNTR VIQASEKLFK IKAPIWYLRS
510 520 530 540 550
LVETILIYKH FTKVSTDPQA PKQELVDFWM DFMVEATNKD KDVTSVRFPV
560 570 580 590 600
LILEPTKVYQ PSYLSINKDA EENTLSIWHV TPDDKKGIHE WNFSAASVRG
610 620 630 640 650
VSISKFDERS CFLYVVNNSE DFQIYFCTEM HCKRFCDLVN TVTEEAWKGS
660 670 680 690 700
DENECESEAL EYDYEYDEHG EKVVLGKGTF GVVYAGRDLS NQVRLAIKEI
710 720 730 740 750
PERDSRYSQP LHEEIALHKH LKHKNIVQYL GSISENGFIK IFMEQVPGGS
760 770 780 790 800
LSALLRSKWG PLKNNEPTIG FYTKQILDGL KYLHDNQIVH RDIKGDNVLI
810 820 830 840 850
NTYSGVLKIS DFGTSKRLAG INPCTETFTG TLQYMAPEII DKGPRGYGKP
860 870 880 890 900
ADIWSLGCTI IEMATGKPPF YELGEPQAAM FKVGMFKIHP EIPDSMSSEA
910 920 930 940 950
KAFILRCFEP DPDSRATAND LLTHEFLTVT SRKKRSKTSS FTALTPGSEY
960 970 980 990 1000
LRSISLPVPV VVEDTSSSSE YGSVSPDNEL CTNPFNFRPS SSSKSYSERE
1010 1020 1030 1040 1050
VKGHRSLFLS IPVENFEDHS APPSPEEKDS GFFMLKKDSE RRATLHRILT
1060 1070 1080 1090 1100
EDREKIVLHL LEALTQGSEE TKLKHQHIST LVASLGDFVR MADRKIIAST
1110 1120 1130 1140 1150
LSQLKLELDF DSTAISQLQV ALFGFQDAVN KVLRNHNIKP HWMFALDNII
1160 1170 1180 1190 1200
RKAVQTAIVI LVPELRPHFT LASESDPAEQ EDIDDDAVPQ GNAALKDMAP
1210 1220 1230 1240 1250
ALVHHDDTVA TSGVSTLSST VSHESQSAQR SISMELGRMK LETKRLLEEL
1260 1270 1280 1290 1300
VEKEREYQAI LQQVLEDREQ EIKLLKCRTG PIDAPVQLVN TRSSLDGDGD
1310 1320 1330 1340 1350
LQLLEWLKLH GADADSIERI IAEDYSLDDI LHYVTRDDLK TLRLRGGVLC
1360
KLWSAITEHR KKPG
Length:1,364
Mass (Da):153,178
Last modified:March 8, 2011 - v1
Checksum:i23338B883591F607
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248523 Genomic DNA. No translation available.
RefSeqiNP_001155222.1. NM_001161750.1.
UniGeneiDr.16458.

Genome annotation databases

EnsembliENSDART00000046641; ENSDARP00000046640; ENSDARG00000005416.
GeneIDi555703.
KEGGidre:555703.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248523 Genomic DNA. No translation available.
RefSeqiNP_001155222.1. NM_001161750.1.
UniGeneiDr.16458.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000046640.

Proteomic databases

PaxDbiE7F2L3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000046641; ENSDARP00000046640; ENSDARG00000005416.
GeneIDi555703.
KEGGidre:555703.

Organism-specific databases

CTDi4217.
ZFINiZDB-GENE-030827-3. map3k5.

Phylogenomic databases

eggNOGiKOG4279. Eukaryota.
ENOG410XQGS. LUCA.
GeneTreeiENSGT00800000124036.
InParanoidiE7F2L3.
KOiK04426.
OMAiTELHCKK.
OrthoDBiEOG7WDN1P.
PhylomeDBiE7F2L3.
TreeFamiTF105115.

Enzyme and pathway databases

ReactomeiR-DRE-2559580. Oxidative Stress Induced Senescence.

Gene expression databases

BgeeiE7F2L3.

Family and domain databases

InterProiIPR025136. DUF4071.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR013761. SAM/pointed.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF13281. DUF4071. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Ensembl
    Submitted (APR-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  2. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiE7F2L3_DANRE
AccessioniPrimary (citable) accession number: E7F2L3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: June 8, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.