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Protein
Submitted name:

Hexose-binding lectin 2

Gene

hbl2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-DRE-166662. Lectin pathway of complement activation.
R-DRE-166663. Initial triggering of complement.
R-DRE-5683826. Surfactant metabolism.
R-DRE-5686938. Regulation of TLR by endogenous ligand.

Names & Taxonomyi

Protein namesi
Submitted name:
Hexose-binding lectin 2Imported
Gene namesi
Name:hbl2Imported
Synonyms:hbl1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 2

Organism-specific databases

ZFINiZDB-GENE-070912-286. hbl2.

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 37Sequence analysisAdd BLAST37
ChainiPRO_500591096438 – 263Sequence analysisAdd BLAST226

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiE7F218.

Expressioni

Gene expression databases

BgeeiENSDARG00000094681.
ExpressionAtlasiE7F218. baseline.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000119245.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini142 – 260C-type lectinInterPro annotationAdd BLAST119

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili107 – 134Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, CollagenSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IS38. Eukaryota.
ENOG410YQHR. LUCA.
GeneTreeiENSGT00700000104102.
InParanoidiE7F218.
OMAiCSVITCG.
OrthoDBiEOG091G0R93.
TreeFamiTF330481.

Family and domain databases

CDDicd03591. CLECT_collectin_like. 1 hit.
Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR008160. Collagen.
IPR033990. Collectin_CTLD.
IPR016187. CTDL_fold.
PfamiView protein in Pfam
PF01391. Collagen. 1 hit.
PF00059. Lectin_C. 1 hit.
SMARTiView protein in SMART
SM00034. CLECT. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiView protein in PROSITE
PS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

E7F218-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPRVKAVHQ MALLKLFLGV FLLLQLVLHV LVGAAEPQTL NCPIYAGVPG
60 70 80 90 100
VPGHNGLPGR DGKDGRDGAT GPKGEKGEPG VSVQGPPGKA GPPGLDGPQG
110 120 130 140 150
ERGPPGSHGS ESVIESLKSE IQNLKAEIDT IEKAASFSNF RRVGQKYYVT
160 170 180 190 200
DGILGNFNDG IKFCKDAGGT LVVPKTAAEN QALVRVSVSS ALSTGKPYIG
210 220 230 240 250
VTDRETEGQF VDIEGKQLTF TNWGPGQPDD YRGGQDCGVI EVSGTWDDGN
260
CGDIRPIICE IDM
Length:263
Mass (Da):27,634
Last modified:December 9, 2015 - v2
Checksum:iA12CCF817D7AD4F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL954692 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSDART00000098531; ENSDARP00000089302; ENSDARG00000094681.

Similar proteinsi

Entry informationi

Entry nameiE7F218_DANRE
AccessioniPrimary (citable) accession number: E7F218
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: December 9, 2015
Last modified: September 27, 2017
This is version 56 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported