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Protein
Submitted name:

Hexose-binding lectin 2

Gene

hbl2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-166662 Lectin pathway of complement activation
R-DRE-166663 Initial triggering of complement
R-DRE-5683826 Surfactant metabolism
R-DRE-5686938 Regulation of TLR by endogenous ligand

Names & Taxonomyi

Protein namesi
Submitted name:
Hexose-binding lectin 2Imported
Gene namesi
Name:hbl2Imported
Synonyms:hbl1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 2

Organism-specific databases

ZFINiZDB-GENE-070912-286 hbl2

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 37Sequence analysisAdd BLAST37
ChainiPRO_500591096438 – 263Sequence analysisAdd BLAST226

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiE7F218

Expressioni

Gene expression databases

BgeeiENSDARG00000094681
ExpressionAtlasiE7F218 baseline

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000119245

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini142 – 260C-type lectinInterPro annotationAdd BLAST119

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili107 – 134Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, CollagenSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IS38 Eukaryota
ENOG410YQHR LUCA
GeneTreeiENSGT00700000104102
InParanoidiE7F218
OrthoDBiEOG091G0R93
TreeFamiTF330481

Family and domain databases

CDDicd03591 CLECT_collectin_like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR018378 C-type_lectin_CS
IPR008160 Collagen
IPR033990 Collectin_CTLD
IPR016187 CTDL_fold
IPR037570 Mannose-binding_protein
PANTHERiPTHR24020:SF0 PTHR24020:SF0, 1 hit
PfamiView protein in Pfam
PF01391 Collagen, 1 hit
PF00059 Lectin_C, 1 hit
SMARTiView protein in SMART
SM00034 CLECT, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
PROSITEiView protein in PROSITE
PS00615 C_TYPE_LECTIN_1, 1 hit
PS50041 C_TYPE_LECTIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

E7F218-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPRVKAVHQ MALLKLFLGV FLLLQLVLHV LVGAAEPQTL NCPIYAGVPG
60 70 80 90 100
VPGHNGLPGR DGKDGRDGAT GPKGEKGEPG VSVQGPPGKA GPPGLDGPQG
110 120 130 140 150
ERGPPGSHGS ESVIESLKSE IQNLKAEIDT IEKAASFSNF RRVGQKYYVT
160 170 180 190 200
DGILGNFNDG IKFCKDAGGT LVVPKTAAEN QALVRVSVSS ALSTGKPYIG
210 220 230 240 250
VTDRETEGQF VDIEGKQLTF TNWGPGQPDD YRGGQDCGVI EVSGTWDDGN
260
CGDIRPIICE IDM
Length:263
Mass (Da):27,634
Last modified:December 9, 2015 - v2
Checksum:iA12CCF817D7AD4F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL954692 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000098531; ENSDARP00000089302; ENSDARG00000094681

Similar proteinsi

Entry informationi

Entry nameiE7F218_DANRE
AccessioniPrimary (citable) accession number: E7F218
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: December 9, 2015
Last modified: March 28, 2018
This is version 61 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health