Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Uncharacterized protein

Gene

arhgef16

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. Rho guanyl-nucleotide exchange factor activity Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_280934. G alpha (12/13) signalling events.
REACT_306531. Rho GTPase cycle.
REACT_347331. NRAGE signals death through JNK.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:arhgef16Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437 Componenti: Chromosome 8

Organism-specific databases

ZFINiZDB-GENE-081104-446. arhgef16.

Expressioni

Gene expression databases

BgeeiE7EXP8.

Family & Domainsi

Sequence similaritiesi

Contains DH (DBL-homology) domain.SAAS annotation
Contains PH domain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00550000074493.
InParanoidiE7EXP8.
TreeFamiTF316357.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR000219. DH-domain.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E7EXP8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHRKSDGST YDQSLLIPES RFNTVLQLDQ SSGKSASSIN LSRLDSPEDE
60 70 80 90 100
RRTVVLSTQS EAARKRGTQQ LIPKSLAVTS RPKNRHHTTV VTLPVPLQAS
110 120 130 140 150
EIGWEDYDSD AGDGVSLRRN RRNKSYRAAI TSLHLDGELQ PESLSPVSDE
160 170 180 190 200
KVVSPKQANK SGRKRTLGRI RNRKHAGSFK DEPRFYQEIK ERGLNVSSLS
210 220 230 240 250
TEEEELSPVG PPGEDQGIVV KNYRAAYITW SQLPQVKDLG ILDFITPEER
260 270 280 290 300
KRQEVIFEII TSEYSYQHSL SILVRHFKDS VDLRKTMTAT EHHHLFSNIS
310 320 330 340 350
VIQDVSKRFF EDLDKRHQAN PVIERISDIV ATYATKHFEP YIVYCSNETF
360 370 380 390 400
QQRTLQKLLS SNSAFRETLK QIETSEDCGG LPMLSFLILP MQRVTRLPLL
410 420 430 440 450
MDTICEKTTK ETAEYYKACW AFKAISKLVK SCNDGARRME RTEQMYTIQK
460 470 480 490 500
QMEFGKIKPF PLVSSSRWLK KSGELAVYTD DLSIFRKAFS FKSYYLFLFN
510 520 530 540 550
DVLIVTKKKS EESYVVLDYA TVEKVEVEEE MSDSKLNLKL MMNPNSDGRS
560 570 580 590 600
EQLVLVAENK LVRAQWVTAL RDVKQTSSID NDDLPQYEAT KAYLPKAPDE
610 620 630 640 650
LSLQQAEVVI VIQEVEGWCY GERMRDGERG WFPASCATQI TNRTAMENNI
660
QRMERLRKET NV
Length:662
Mass (Da):75,870
Last modified:March 8, 2011 - v1
Checksum:iED2192CFFEBBF818
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX000472 Genomic DNA. No translation available.
CR792439 Genomic DNA. No translation available.
CT573138 Genomic DNA. No translation available.
RefSeqiXP_005167338.1. XM_005167281.2.
UniGeneiDr.78159.

Genome annotation databases

EnsembliENSDART00000131137; ENSDARP00000111989; ENSDARG00000077114.
GeneIDi567180.
KEGGidre:567180.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX000472 Genomic DNA. No translation available.
CR792439 Genomic DNA. No translation available.
CT573138 Genomic DNA. No translation available.
RefSeqiXP_005167338.1. XM_005167281.2.
UniGeneiDr.78159.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000131137; ENSDARP00000111989; ENSDARG00000077114.
GeneIDi567180.
KEGGidre:567180.

Organism-specific databases

CTDi27237.
ZFINiZDB-GENE-081104-446. arhgef16.

Phylogenomic databases

GeneTreeiENSGT00550000074493.
InParanoidiE7EXP8.
TreeFamiTF316357.

Enzyme and pathway databases

ReactomeiREACT_280934. G alpha (12/13) signalling events.
REACT_306531. Rho GTPase cycle.
REACT_347331. NRAGE signals death through JNK.

Miscellaneous databases

PROiE7EXP8.

Gene expression databases

BgeeiE7EXP8.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR000219. DH-domain.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Ensembl
    Submitted (APR-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  2. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiE7EXP8_DANRE
AccessioniPrimary (citable) accession number: E7EXP8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: April 1, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.