E7EXP8 (E7EXP8_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSDARP00000111989

Gene names

Name:

arhgef16 Ensembl ENSDARP00000111989 ZFIN ZDB-GENE-081104-446

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome] Ensembl ENSDARP00000111989

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	662 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 DH (DBL-homology) domain. SAAS SAAS000219 Contains 1 PH domain. SAAS SAAS000219 RuleBase RU003350 Contains 1 SH3 domain. RuleBase RU003338

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	regulation of Rho protein signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	Rho guanyl-nucleotide exchange factor activity Inferred from electronic annotation. Source: InterPro phospholipid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E7EXP8 [UniParc]. Last modified March 8, 2011. Version 1. Checksum: ED2192CFFEBBF818	FASTA	662	75,870
	10 20 30 40 50 60 MSHRKSDGST YDQSLLIPES RFNTVLQLDQ SSGKSASSIN LSRLDSPEDE RRTVVLSTQS 70 80 90 100 110 120 EAARKRGTQQ LIPKSLAVTS RPKNRHHTTV VTLPVPLQAS EIGWEDYDSD AGDGVSLRRN 130 140 150 160 170 180 RRNKSYRAAI TSLHLDGELQ PESLSPVSDE KVVSPKQANK SGRKRTLGRI RNRKHAGSFK 190 200 210 220 230 240 DEPRFYQEIK ERGLNVSSLS TEEEELSPVG PPGEDQGIVV KNYRAAYITW SQLPQVKDLG 250 260 270 280 290 300 ILDFITPEER KRQEVIFEII TSEYSYQHSL SILVRHFKDS VDLRKTMTAT EHHHLFSNIS 310 320 330 340 350 360 VIQDVSKRFF EDLDKRHQAN PVIERISDIV ATYATKHFEP YIVYCSNETF QQRTLQKLLS 370 380 390 400 410 420 SNSAFRETLK QIETSEDCGG LPMLSFLILP MQRVTRLPLL MDTICEKTTK ETAEYYKACW 430 440 450 460 470 480 AFKAISKLVK SCNDGARRME RTEQMYTIQK QMEFGKIKPF PLVSSSRWLK KSGELAVYTD 490 500 510 520 530 540 DLSIFRKAFS FKSYYLFLFN DVLIVTKKKS EESYVVLDYA TVEKVEVEEE MSDSKLNLKL 550 560 570 580 590 600 MMNPNSDGRS EQLVLVAENK LVRAQWVTAL RDVKQTSSID NDDLPQYEAT KAYLPKAPDE 610 620 630 640 650 660 LSLQQAEVVI VIQEVEGWCY GERMRDGERG WFPASCATQI TNRTAMENNI QRMERLRKET NV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000111989.
[2]	Ensembl Submitted (APR-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000111989.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000111989.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX000472 Genomic DNA. No translation available. CR792439 Genomic DNA. No translation available. CT573138 Genomic DNA. No translation available.
IPI	IPI00996933.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000131137; ENSDARP00000111989; ENSDARG00000077114.
Organism-specific databases
ZFIN	ZDB-GENE-081104-446. arhgef16.
Phylogenomic databases
GeneTree	ENSGT00550000074493.
Family and domain databases
Gene3D	1.20.900.10. 1 hit. 2.30.29.30. 1 hit.
InterPro	IPR000219. DH-domain. IPR011993. PH_like_dom. IPR001849. Pleckstrin_homology. IPR001452. SH3_domain. [Graphical view]
Pfam	PF00169. PH. 1 hit. PF00621. RhoGEF. 1 hit. PF00018. SH3_1. 1 hit. [Graphical view]
SMART	SM00233. PH. 1 hit. SM00325. RhoGEF. 1 hit. SM00326. SH3. 1 hit. [Graphical view]
SUPFAM	SSF48065. DH-domain. 1 hit. SSF50044. SH3. 1 hit.
PROSITE	PS50010. DH_2. 1 hit. PS50003. PH_DOMAIN. 1 hit. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E7EXP8_DANRE

Accession

Primary (citable) accession number: E7EXP8

Entry history

Integrated into UniProtKB/TrEMBL:	March 8, 2011
Last sequence update:	March 8, 2011
Last modified:	March 6, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)