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E7EX57

- E7EX57_HUMAN

UniProt

E7EX57 - E7EX57_HUMAN

Protein
Submitted name:

Multidrug and toxin extrusion protein 1

Gene

SLC47A1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (08 Mar 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. antiporter activity Source: InterPro
    2. drug transmembrane transporter activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Multidrug and toxin extrusion protein 1Imported
    Gene namesi
    Name:SLC47A1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 17

    Organism-specific databases

    HGNCiHGNC:25588. SLC47A1.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro

    Expressioni

    Gene expression databases

    ArrayExpressiE7EX57.
    BgeeiE7EX57.

    Structurei

    3D structure databases

    ProteinModelPortaliE7EX57.
    SMRiE7EX57. Positions 28-414.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    InterProiIPR002528. MATE.
    [Graphical view]
    PfamiPF01554. MatE. 2 hits.
    [Graphical view]
    TIGRFAMsiTIGR00797. matE. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E7EX57-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEAPEEPAPV RGGPEATLEV RGSRCLRLSA FREELRALLV LAGPAFLVQL    50
    MVFLISFISS VFCGHLGKLE LDAVTLAIAT YGSQNLKHVG VILQRSALVL 100
    LLCCFPCWAL FLNTQHILLL FRQDPDVSRL TQTYVTIFIP ALPATFLYML 150
    QVKYLLNQGI VLPQIVTGVA ANLVNALANY LFLHQLHLGV IGSALANLIS 200
    QYTLALLLFL YILGKKLHQA TWGGWSLECL QDWASFLRLA IPSMLMLCME 250
    WWAYEVGSFL SGILGMVELG AQSIVYELAI IVYMVPAGFS VAASVRVGNA 300
    LGAGDMEQAR KSSTVSLLIT VLFAVAFSVL LLSCKDHVGY IFTTDRDIIN 350
    LVAQVVPIYA VSHLFEALAC TSGGVLRGSG NQKVGAIVNT IGYYVVGLPI 400
    GIALMFATTL GVMGSGTRQF ESKQRASEWE FCSPSGSASP RVP 443
    Length:443
    Mass (Da):48,027
    Last modified:March 8, 2011 - v1
    Checksum:i5255E025EFD592F2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004448 Genomic DNA. No translation available.
    AC025627 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000436810; ENSP00000407155; ENSG00000142494.
    UCSCiuc010vyz.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004448 Genomic DNA. No translation available.
    AC025627 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E7EX57.
    SMRi E7EX57. Positions 28-414.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000436810 ; ENSP00000407155 ; ENSG00000142494 .
    UCSCi uc010vyz.1. human.

    Organism-specific databases

    HGNCi HGNC:25588. SLC47A1.
    GenAtlasi Search...

    Miscellaneous databases

    NextBioi 35500909.

    Gene expression databases

    ArrayExpressi E7EX57.
    Bgeei E7EX57.

    Family and domain databases

    InterProi IPR002528. MATE.
    [Graphical view ]
    Pfami PF01554. MatE. 2 hits.
    [Graphical view ]
    TIGRFAMsi TIGR00797. matE. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
      Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
      , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
      Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
    3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiE7EX57_HUMAN
    AccessioniPrimary (citable) accession number: E7EX57
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3