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Protein
Submitted name:

Multidrug and toxin extrusion protein 1

Gene

SLC47A1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Multidrug and toxin extrusion protein 1Imported
Gene namesi
Name:SLC47A1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:25588. SLC47A1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE7EX57.
ExpressionAtlasiE7EX57. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE7EX57.
SMRiE7EX57. Positions 28-414.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000015713.

Family and domain databases

InterProiIPR002528. MATE.
[Graphical view]
PfamiPF01554. MatE. 2 hits.
[Graphical view]
TIGRFAMsiTIGR00797. matE. 1 hit.

Sequencei

Sequence statusi: Complete.

E7EX57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAPEEPAPV RGGPEATLEV RGSRCLRLSA FREELRALLV LAGPAFLVQL
60 70 80 90 100
MVFLISFISS VFCGHLGKLE LDAVTLAIAT YGSQNLKHVG VILQRSALVL
110 120 130 140 150
LLCCFPCWAL FLNTQHILLL FRQDPDVSRL TQTYVTIFIP ALPATFLYML
160 170 180 190 200
QVKYLLNQGI VLPQIVTGVA ANLVNALANY LFLHQLHLGV IGSALANLIS
210 220 230 240 250
QYTLALLLFL YILGKKLHQA TWGGWSLECL QDWASFLRLA IPSMLMLCME
260 270 280 290 300
WWAYEVGSFL SGILGMVELG AQSIVYELAI IVYMVPAGFS VAASVRVGNA
310 320 330 340 350
LGAGDMEQAR KSSTVSLLIT VLFAVAFSVL LLSCKDHVGY IFTTDRDIIN
360 370 380 390 400
LVAQVVPIYA VSHLFEALAC TSGGVLRGSG NQKVGAIVNT IGYYVVGLPI
410 420 430 440
GIALMFATTL GVMGSGTRQF ESKQRASEWE FCSPSGSASP RVP
Length:443
Mass (Da):48,027
Last modified:March 8, 2011 - v1
Checksum:i5255E025EFD592F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004448 Genomic DNA. No translation available.
AC025627 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000436810; ENSP00000407155; ENSG00000142494.
UCSCiuc010vyz.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004448 Genomic DNA. No translation available.
AC025627 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE7EX57.
SMRiE7EX57. Positions 28-414.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000436810; ENSP00000407155; ENSG00000142494.
UCSCiuc010vyz.1. human.

Organism-specific databases

HGNCiHGNC:25588. SLC47A1.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000015713.

Miscellaneous databases

ChiTaRSiSLC47A1. human.
NextBioi35500909.

Gene expression databases

BgeeiE7EX57.
ExpressionAtlasiE7EX57. baseline and differential.

Family and domain databases

InterProiIPR002528. MATE.
[Graphical view]
PfamiPF01554. MatE. 2 hits.
[Graphical view]
TIGRFAMsiTIGR00797. matE. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiE7EX57_HUMAN
AccessioniPrimary (citable) accession number: E7EX57
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 22, 2015
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.