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E7EX57

- E7EX57_HUMAN

UniProt

E7EX57 - E7EX57_HUMAN

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Protein
Submitted name:

Multidrug and toxin extrusion protein 1

Gene

SLC47A1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. antiporter activity Source: InterPro
  2. drug transmembrane transporter activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Multidrug and toxin extrusion protein 1Imported
Gene namesi
Name:SLC47A1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:25588. SLC47A1.

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE7EX57.
ExpressionAtlasiE7EX57. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE7EX57.
SMRiE7EX57. Positions 28-414.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000015713.

Family and domain databases

InterProiIPR002528. MATE.
[Graphical view]
PfamiPF01554. MatE. 2 hits.
[Graphical view]
TIGRFAMsiTIGR00797. matE. 1 hit.

Sequencei

Sequence statusi: Complete.

E7EX57-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEAPEEPAPV RGGPEATLEV RGSRCLRLSA FREELRALLV LAGPAFLVQL
60 70 80 90 100
MVFLISFISS VFCGHLGKLE LDAVTLAIAT YGSQNLKHVG VILQRSALVL
110 120 130 140 150
LLCCFPCWAL FLNTQHILLL FRQDPDVSRL TQTYVTIFIP ALPATFLYML
160 170 180 190 200
QVKYLLNQGI VLPQIVTGVA ANLVNALANY LFLHQLHLGV IGSALANLIS
210 220 230 240 250
QYTLALLLFL YILGKKLHQA TWGGWSLECL QDWASFLRLA IPSMLMLCME
260 270 280 290 300
WWAYEVGSFL SGILGMVELG AQSIVYELAI IVYMVPAGFS VAASVRVGNA
310 320 330 340 350
LGAGDMEQAR KSSTVSLLIT VLFAVAFSVL LLSCKDHVGY IFTTDRDIIN
360 370 380 390 400
LVAQVVPIYA VSHLFEALAC TSGGVLRGSG NQKVGAIVNT IGYYVVGLPI
410 420 430 440
GIALMFATTL GVMGSGTRQF ESKQRASEWE FCSPSGSASP RVP
Length:443
Mass (Da):48,027
Last modified:March 8, 2011 - v1
Checksum:i5255E025EFD592F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004448 Genomic DNA. No translation available.
AC025627 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000436810; ENSP00000407155; ENSG00000142494.
UCSCiuc010vyz.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004448 Genomic DNA. No translation available.
AC025627 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali E7EX57.
SMRi E7EX57. Positions 28-414.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000436810 ; ENSP00000407155 ; ENSG00000142494 .
UCSCi uc010vyz.1. human.

Organism-specific databases

HGNCi HGNC:25588. SLC47A1.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00390000015713.

Miscellaneous databases

ChiTaRSi SLC47A1. human.
NextBioi 35500909.

Gene expression databases

Bgeei E7EX57.
ExpressionAtlasi E7EX57. baseline and differential.

Family and domain databases

InterProi IPR002528. MATE.
[Graphical view ]
Pfami PF01554. MatE. 2 hits.
[Graphical view ]
TIGRFAMsi TIGR00797. matE. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiE7EX57_HUMAN
AccessioniPrimary (citable) accession number: E7EX57
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: November 26, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3