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Protein
Submitted name:

Mitogen-activated protein kinase 14

Gene

MAPK14

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

SignaLinkiE7EX54.

Names & Taxonomyi

Protein namesi
Submitted name:
Mitogen-activated protein kinase 14Imported
Gene namesi
Name:MAPK14Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:6876. MAPK14.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000112062.

PTM / Processingi

Proteomic databases

PaxDbiE7EX54.
PeptideAtlasiE7EX54.
PRIDEiE7EX54.

Expressioni

Gene expression databases

BgeeiENSG00000112062.
ExpressionAtlasiE7EX54. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000229794.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 132Protein kinaseInterPro annotationAdd BLAST132

Phylogenomic databases

eggNOGiKOG0660. Eukaryota.
ENOG410XNY0. LUCA.
GeneTreeiENSGT00550000074271.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E7EX54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHENVIGLL DVFTPARSLE EFNDVYLVTH LMGADLNNIV KCQKLTDDHV
60 70 80 90 100
QFLIYQILRG LKYIHSADII HRDLKPSNLA VNEDCELKIL DFGLARHTDD
110 120 130
EMTGYVATRW YRAPEIMLNW MHYNQTVDIW SV
Length:132
Mass (Da):15,447
Last modified:October 5, 2016 - v8
Checksum:iAB71B4BB62107D3D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei132Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z95152 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000472333; ENSP00000419141; ENSG00000112062.
UCSCiuc063ode.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z95152 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000229794.

Proteomic databases

PaxDbiE7EX54.
PeptideAtlasiE7EX54.
PRIDEiE7EX54.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000472333; ENSP00000419141; ENSG00000112062.
UCSCiuc063ode.1. human.

Organism-specific databases

HGNCiHGNC:6876. MAPK14.
OpenTargetsiENSG00000112062.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0660. Eukaryota.
ENOG410XNY0. LUCA.
GeneTreeiENSGT00550000074271.

Enzyme and pathway databases

SignaLinkiE7EX54.

Miscellaneous databases

ChiTaRSiMAPK14. human.

Gene expression databases

BgeeiENSG00000112062.
ExpressionAtlasiE7EX54. baseline and differential.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE7EX54_HUMAN
AccessioniPrimary (citable) accession number: E7EX54
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: October 5, 2016
Last modified: November 30, 2016
This is version 47 of the entry and version 8 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.