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Protein
Submitted name:

ATP-binding cassette sub-family G member 5

Gene

ABCG5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-binding cassette sub-family G member 5Imported
Gene namesi
Name:ABCG5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000138075.11
HGNCiHGNC:13886 ABCG5

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei213 – 234HelicalSequence analysisAdd BLAST22
Transmembranei294 – 319HelicalSequence analysisAdd BLAST26
Transmembranei331 – 352HelicalSequence analysisAdd BLAST22
Transmembranei358 – 378HelicalSequence analysisAdd BLAST21
Transmembranei454 – 473HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000138075

PTM / Processingi

Proteomic databases

PeptideAtlasiE7EX35
PRIDEiE7EX35

Expressioni

Gene expression databases

BgeeiENSG00000138075
ExpressionAtlasiE7EX35 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE7EX35
SMRiE7EX35
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 130ABC transporterInterPro annotationAdd BLAST129
Domaini197 – 409ABC2_membraneInterPro annotationAdd BLAST213

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0061 Eukaryota
COG1131 LUCA
GeneTreeiENSGT00910000144282

Family and domain databases

InterProiView protein in InterPro
IPR013525 ABC_2_trans
IPR003439 ABC_transporter-like
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF01061 ABC2_membrane, 1 hit
PF00005 ABC_tran, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

E7EX35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCILGSSGSG KTTLLDAMSG RLGRAGTFLG EVYVNGRALR REQFQDCFSY
60 70 80 90 100
VLQSDTLLSS LTVRETLHYT ALLAIRRGNP GSFQKKVEAV MAELSLSHVA
110 120 130 140 150
DRLIGNYSLG GISTGERRRV SIAAQLLQDP MDLTSVDTQS KEREIETSKR
160 170 180 190 200
VQMIESAYKK SAICHKTLKN IERMKHLKTL PMVPFKTKDS PGVFSKLGVL
210 220 230 240 250
LRRVTRNLVR NKLAVITRLL QNLIMGLFLL FFVLRVRSNV LKGAIQDRVG
260 270 280 290 300
LLYQFVGATP YTGMLNAVNL FPVLRAVSDQ ESQDGLYQKW QMMLAYALHV
310 320 330 340 350
LPFSVVATMI FSSVCYWTLG LHPEVARFGY FSAALLAPHL IGEFLTLVLL
360 370 380 390 400
GIVQNPNIVN SVVALLSIAG VLVGSGFLRN IQEMPIPFKI ISYFTFQKYC
410 420 430 440 450
SEILVVNEFY GLNFTCGSSN VSVTTNPMCA FTQGIQFIEK TCPGATSRFT
460 470 480
MNFLILYSFI PALVILGIVV FKIRDHLISR
Length:480
Mass (Da):53,402
Last modified:March 8, 2011 - v1
Checksum:i4C6B60F35509B3DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011242 Genomic DNA No translation available.
AC108476 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000405322; ENSP00000384513; ENSG00000138075
UCSCiuc002rto.4 human

Similar proteinsi

Entry informationi

Entry nameiE7EX35_HUMAN
AccessioniPrimary (citable) accession number: E7EX35
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: March 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health