Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cyclic AMP-responsive element-binding protein 1

Gene

CREB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclic AMP-responsive element-binding protein 1Imported
Gene namesi
Name:CREB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000118260.14
HGNCiHGNC:2345 CREB1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000118260

PTM / Processingi

Proteomic databases

MaxQBiE7EWP8
PeptideAtlasiE7EWP8
PRIDEiE7EWP8

Expressioni

Gene expression databases

BgeeiENSG00000118260
ExpressionAtlasiE7EWP8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE7EWP8
SMRiE7EWP8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini101 – 160KIDInterPro annotationAdd BLAST60

Phylogenomic databases

eggNOGiKOG3584 Eukaryota
ENOG410ZZJZ LUCA
GeneTreeiENSGT00390000008655

Family and domain databases

InterProiView protein in InterPro
IPR003102 Coactivator_CBP_pKID
IPR029802 CREB1
IPR001630 Leuzip_CREB
PANTHERiPTHR22952:SF200 PTHR22952:SF200, 1 hit
PfamiView protein in Pfam
PF02173 pKID, 1 hit
PRINTSiPR00041 LEUZIPPRCREB
PROSITEiView protein in PROSITE
PS50953 KID, 1 hit

Sequencei

Sequence statusi: Fragment.

E7EWP8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTMESGAENQ QSGDAAVTEA ENQQMTVQAQ PQIATLAQVS MPAAHATSSA
60 70 80 90 100
PTVTLVQLPN GQTVQVHGVI QAAQPSVIQS PQVQTVQSSC KDLKRLFSGT
110 120 130 140 150
QISTIAESED SQESVDSVTD SQKRREILSR RPSYRKILND LSSDAPGVPR
160 170 180
IEEEKSEEET SAPAITTVTV PTPIYQTSSG QY
Length:182
Mass (Da):19,485
Last modified:March 8, 2011 - v1
Checksum:i869266E2C387A018
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei182Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009298 Genomic DNA No translation available.
AC079767 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000445803; ENSP00000407227; ENSG00000118260
UCSCiuc061rvc.1 human

Similar proteinsi

Entry informationi

Entry nameiE7EWP8_HUMAN
AccessioniPrimary (citable) accession number: E7EWP8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: April 25, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health