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Protein
Submitted name:

Thioredoxin reductase 2, mitochondrial

Gene

TXNRD2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Thioredoxin reductase 2, mitochondrialImported
Gene namesi
Name:TXNRD2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000184470.20
HGNCiHGNC:18155 TXNRD2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000184470

PTM / Processingi

Proteomic databases

MaxQBiE7EWK1
PeptideAtlasiE7EWK1
PRIDEiE7EWK1

Expressioni

Gene expression databases

BgeeiENSG00000184470
ExpressionAtlasiE7EWK1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE7EWK1
SMRiE7EWK1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 316FAD/NAD-binding_domInterPro annotationAdd BLAST277

Phylogenomic databases

eggNOGiKOG0405 Eukaryota
COG1249 LUCA
GeneTreeiENSGT00390000007578

Family and domain databases

Gene3Di3.50.50.601 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR023753 FAD/NAD-binding_dom
IPR012999 Pyr_OxRdtase_I_AS
PfamiView protein in Pfam
PF07992 Pyr_redox_2, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
PROSITEiView protein in PROSITE
PS00076 PYRIDINE_REDOX_1, 1 hit

Sequencei

Sequence statusi: Complete.

E7EWK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAMAVALRG LGGRFRWRTQ AVAGGVRGAA RGAAAGQRDY DLLVVGGGSG
60 70 80 90 100
GLACAKEAAQ LGRKVAVVDY VEPSPQGTRW GLGGTCVNVG CIPKKLMHQA
110 120 130 140 150
ALLGGLIQDA PNYGWEVAQP VPHDWRKMAE AVQNHVKSLN WGHRVQLQDR
160 170 180 190 200
KVKYFNIKAS FVDEHTVCGV AKGGKEILLS ADHIIIATGG RPRYPTHIEG
210 220 230 240 250
ALEYGITSDD IFWLKESPGK TLVVGASYVA LECAGFLTGI GLDTTIMMRS
260 270 280 290 300
IPLRGFDQQM SSMVIEHMAS HGTRFLRGCA PSRVRRLPDG QLQVTWEDST
310 320 330
TGKEDTGTFD TVLWAIAPCI SACLPTTVGH AGKNQRRD
Length:338
Mass (Da):36,303
Last modified:March 8, 2011 - v1
Checksum:i2F49169F5A22CA07
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000078 Genomic DNA No translation available.
AC000090 Genomic DNA No translation available.
RefSeqiNP_001269441.1, NM_001282512.1
UniGeneiHs.443430

Genome annotation databases

EnsembliENST00000334363; ENSP00000334451; ENSG00000184470
GeneIDi10587
UCSCiuc010grv.2 human

Similar proteinsi

Entry informationi

Entry nameiE7EWK1_HUMAN
AccessioniPrimary (citable) accession number: E7EWK1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: March 28, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported