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Protein
Submitted name:

Thioredoxin reductase 2, mitochondrial

Gene

TXNRD2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Thioredoxin reductase 2, mitochondrialImported
Gene namesi
Name:TXNRD2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000184470.20.
HGNCiHGNC:18155. TXNRD2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000184470.

PTM / Processingi

Proteomic databases

MaxQBiE7EWK1.
PaxDbiE7EWK1.
PeptideAtlasiE7EWK1.
PRIDEiE7EWK1.

Expressioni

Gene expression databases

BgeeiENSG00000184470.
ExpressionAtlasiE7EWK1. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE7EWK1.
SMRiE7EWK1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 316FAD/NAD-binding_domInterPro annotationAdd BLAST277

Phylogenomic databases

eggNOGiKOG0405. Eukaryota.
COG1249. LUCA.
GeneTreeiENSGT00390000007578.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
InterProiView protein in InterPro
IPR023753. FAD/NAD-binding_dom.
IPR012999. Pyr_OxRdtase_I_AS.
PfamiView protein in Pfam
PF07992. Pyr_redox_2. 1 hit.
SUPFAMiSSF51905. SSF51905. 1 hit.
PROSITEiView protein in PROSITE
PS00076. PYRIDINE_REDOX_1. 1 hit.

Sequencei

Sequence statusi: Complete.

E7EWK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAMAVALRG LGGRFRWRTQ AVAGGVRGAA RGAAAGQRDY DLLVVGGGSG
60 70 80 90 100
GLACAKEAAQ LGRKVAVVDY VEPSPQGTRW GLGGTCVNVG CIPKKLMHQA
110 120 130 140 150
ALLGGLIQDA PNYGWEVAQP VPHDWRKMAE AVQNHVKSLN WGHRVQLQDR
160 170 180 190 200
KVKYFNIKAS FVDEHTVCGV AKGGKEILLS ADHIIIATGG RPRYPTHIEG
210 220 230 240 250
ALEYGITSDD IFWLKESPGK TLVVGASYVA LECAGFLTGI GLDTTIMMRS
260 270 280 290 300
IPLRGFDQQM SSMVIEHMAS HGTRFLRGCA PSRVRRLPDG QLQVTWEDST
310 320 330
TGKEDTGTFD TVLWAIAPCI SACLPTTVGH AGKNQRRD
Length:338
Mass (Da):36,303
Last modified:March 8, 2011 - v1
Checksum:i2F49169F5A22CA07
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000078 Genomic DNA. No translation available.
AC000090 Genomic DNA. No translation available.
RefSeqiNP_001269441.1. NM_001282512.1.
UniGeneiHs.443430.

Genome annotation databases

EnsembliENST00000334363; ENSP00000334451; ENSG00000184470.
GeneIDi10587.
UCSCiuc010grv.2. human.

Similar proteinsi

Entry informationi

Entry nameiE7EWK1_HUMAN
AccessioniPrimary (citable) accession number: E7EWK1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: September 27, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported