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E7EVZ9

- E7EVZ9_HUMAN

UniProt

E7EVZ9 - E7EVZ9_HUMAN

Protein

Integrin beta

Gene

ITGB2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    GO - Molecular functioni

    1. receptor activity Source: InterPro

    GO - Biological processi

    1. cell-matrix adhesion Source: InterPro
    2. integrin-mediated signaling pathway Source: UniProtKB-KW
    3. multicellular organismal development Source: InterPro

    Keywords - Molecular functioni

    IntegrinUniRule annotation

    Keywords - Biological processi

    Cell adhesionUniRule annotation

    Enzyme and pathway databases

    SignaLinkiE7EVZ9.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Integrin betaUniRule annotation
    Gene namesi
    Name:ITGB2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 21

    Organism-specific databases

    HGNCiHGNC:6155. ITGB2.

    Subcellular locationi

    Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

    GO - Cellular componenti

    1. integrin complex Source: InterPro

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiE7EVZ9.
    BgeeiE7EVZ9.

    Structurei

    3D structure databases

    ProteinModelPortaliE7EVZ9.
    SMRiE7EVZ9. Positions 23-166.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the integrin beta chain family.UniRule annotation

    Keywords - Domaini

    TransmembraneUniRule annotation

    Family and domain databases

    Gene3Di3.40.50.410. 1 hit.
    InterProiIPR015812. Integrin_bsu.
    IPR015439. Integrin_bsu-2.
    IPR002369. Integrin_bsu_N.
    IPR016201. Plexin-like_fold.
    IPR002035. VWF_A.
    [Graphical view]
    PANTHERiPTHR10082. PTHR10082. 1 hit.
    PTHR10082:SF15. PTHR10082:SF15. 1 hit.
    PfamiPF00362. Integrin_beta. 1 hit.
    [Graphical view]
    PRINTSiPR01186. INTEGRINB.
    SMARTiSM00187. INB. 1 hit.
    SM00423. PSI. 1 hit.
    [Graphical view]
    SUPFAMiSSF103575. SSF103575. 1 hit.
    SSF53300. SSF53300. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    E7EVZ9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLGLRPPLLA LVGLLSLGCV LSQECTKFKV SSCRECIESG PGCTWCQKLN    50
    FTGPGDPDSI RCDTRPQLLM RGCAADDIMD PTSLAETQED HNGGQKQLSP 100
    QKVTLYLRPG QAAAFNVTFR RAKGYPIDLY YLMDLSYSML DDLRNVKKLG 150
    GDLLRALNEI TESGRI 166
    Length:166
    Mass (Da):18,288
    Last modified:March 8, 2011 - v1
    Checksum:i74B92D6DE99BB7D3
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei166 – 1661Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL773603 Genomic DNA. No translation available.
    AL844907 Genomic DNA. No translation available.
    AL844908 Genomic DNA. No translation available.
    KC877928 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000523663; ENSP00000428503; ENSG00000160255.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL773603 Genomic DNA. No translation available.
    AL844907 Genomic DNA. No translation available.
    AL844908 Genomic DNA. No translation available.
    KC877928 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E7EVZ9.
    SMRi E7EVZ9. Positions 23-166.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000523663 ; ENSP00000428503 ; ENSG00000160255 .

    Organism-specific databases

    HGNCi HGNC:6155. ITGB2.
    GenAtlasi Search...

    Enzyme and pathway databases

    SignaLinki E7EVZ9.

    Miscellaneous databases

    ChiTaRSi ITGB2. human.
    NextBioi 35500715.

    Gene expression databases

    ArrayExpressi E7EVZ9.
    Bgeei E7EVZ9.

    Family and domain databases

    Gene3Di 3.40.50.410. 1 hit.
    InterProi IPR015812. Integrin_bsu.
    IPR015439. Integrin_bsu-2.
    IPR002369. Integrin_bsu_N.
    IPR016201. Plexin-like_fold.
    IPR002035. VWF_A.
    [Graphical view ]
    PANTHERi PTHR10082. PTHR10082. 1 hit.
    PTHR10082:SF15. PTHR10082:SF15. 1 hit.
    Pfami PF00362. Integrin_beta. 1 hit.
    [Graphical view ]
    PRINTSi PR01186. INTEGRINB.
    SMARTi SM00187. INB. 1 hit.
    SM00423. PSI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF103575. SSF103575. 1 hit.
    SSF53300. SSF53300. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of human chromosome 21."
      Chromosome 21 mapping and sequencing consortium
      Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A.
      , Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.
      Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE7EVZ9_HUMAN
    AccessioniPrimary (citable) accession number: E7EVZ9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3