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Protein
Submitted name:

Caspase-8

Gene

CASP8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Caspase-8Imported
Gene namesi
Name:CASP8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000064012.21.
HGNCiHGNC:1509. CASP8.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000064012.

PTM / Processingi

Proteomic databases

MaxQBiE7EVN1.
PaxDbiE7EVN1.
PeptideAtlasiE7EVN1.
PRIDEiE7EVN1.

Expressioni

Gene expression databases

BgeeiENSG00000064012.
ExpressionAtlasiE7EVN1. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE7EVN1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 80DEDInterPro annotationAdd BLAST79
Domaini100 – 124DEDInterPro annotationAdd BLAST25

Phylogenomic databases

eggNOGiKOG3573. Eukaryota.
ENOG410ZQIE. LUCA.
GeneTreeiENSGT00760000118912.

Family and domain databases

InterProiView protein in InterPro
IPR033170. Caspase-8.
IPR011029. DEATH-like_dom.
IPR001875. DED_dom.
PANTHERiPTHR10454:SF162. PTHR10454:SF162. 1 hit.
PfamiView protein in Pfam
PF01335. DED. 1 hit.
SMARTiView protein in SMART
SM00031. DED. 1 hit.
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiView protein in PROSITE
PS50168. DED. 2 hits.

Sequencei

Sequence statusi: Fragment.

E7EVN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFSRNLYDI GEQLDSEDLA SLKFLSLDYI PQRKQEPIKD ALMLFQRLQE
60 70 80 90 100
KRMLEESNLS FLKELLFRIN RLDLLITYLN TRKEEMEREL QTPGRAQISA
110 120
YRVMLYQISE EVSRSELRSF KFLL
Length:124
Mass (Da):14,930
Last modified:March 8, 2011 - v1
Checksum:i39605681A0A35B4C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei124Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007256 Genomic DNA. No translation available.
AC007283 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000440732; ENSP00000396869; ENSG00000064012.
UCSCiuc061rju.1. human.

Similar proteinsi

Entry informationi

Entry nameiE7EVN1_HUMAN
AccessioniPrimary (citable) accession number: E7EVN1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: October 25, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported