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Protein
Submitted name:

Cytoplasmic FMR1-interacting protein 2

Gene

CYFIP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Cytoplasmic FMR1-interacting protein 2Imported
Gene namesi
Name:CYFIP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

HGNCiHGNC:13760. CYFIP2.

PTM / Processingi

Proteomic databases

EPDiE7EVJ5.
PaxDbiE7EVJ5.
PeptideAtlasiE7EVJ5.
PRIDEiE7EVJ5.

Expressioni

Gene expression databases

BgeeiE7EVJ5.
ExpressionAtlasiE7EVJ5. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000325817.

Structurei

3D structure databases

ProteinModelPortaliE7EVJ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG3534. Eukaryota.
ENOG410XPKW. LUCA.
GeneTreeiENSGT00500000044831.
TreeFamiTF312925.

Family and domain databases

InterProiIPR008081. Cytoplasmic_FMR1-int.
IPR009828. DUF1394.
[Graphical view]
PANTHERiPTHR12195. PTHR12195. 1 hit.
PfamiPF07159. DUF1394. 1 hit.
PF05994. FragX_IP. 1 hit.
[Graphical view]
PIRSFiPIRSF008153. FMR1_interacting. 1 hit.
PRINTSiPR01698. CYTOFMRPINTP.

Sequencei

Sequence statusi: Complete.

E7EVJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTHVTLEDA LSNVDLLEEL PLPDQQPCIE PPPSSIMYQA NFDTNFEDRN
60 70 80 90 100
AFVTGIARYI EQATVHSSMV KCNEQPNRVE IYEKTVEVLE PEVTKLMKFM
110 120 130 140 150
YFQRKAIERF CSEVKRLCHA ERRKDFVSEA YLLTLGKFIN MFAVLDELKN
160 170 180 190 200
MKCSVKNDHS AYKRAAQFLR KMADPQSIQE SQNLSMFLAN HNRITQCLHQ
210 220 230 240 250
QLEVIPGYEE LLADIVNICV DYYENKMYLT PSEKHMLLKV MGFGLYLMDG
260 270 280 290 300
NVSNIYKLDA KKRINLSKID KFFKQLQVVP LFGDMQIELA RYIKTSAHYE
310 320 330 340 350
ENKSKWTCTQ SSISPQYNIC EQMVQIRDDH IRFISELARY SNSEVVTGSG
360 370 380 390 400
LDSQKSDEEY RELFDLALRG LQLLSKWSAH VMEVYSWKLV HPTDKFCNKD
410 420 430 440 450
CPGTAEEYER ATRYNYTSEE KFAFVEVIAM IKGLQVLMGR MESVFNQAIR
460 470 480 490 500
NTIYAALQDF AQVTLREPLR QAVRKKKNVL ISVLQAIRKT ICDWEGGREP
510 520 530 540 550
PNDPCLRGEK DPKGGFDIKV PRRAVGPSST QLYMVRTMLE SLIADKSGSK
560 570 580 590 600
KTLRSSLDGP IVLAIEDFHK QSFFFTHLLN ISEALQQCCD LSQLWFREFF
610 620 630 640 650
LELTMGRRIQ FPIEMSMPWI LTDHILETKE PSMMEYVLYP LDLYNDSAYY
660 670 680 690 700
ALTKFKKQFL YDEIEAEVNL CFDQFVYKLA DQIFAYYKAM AGSVLLDKRF
710 720 730 740 750
RAECKNYGVI IPYPPSNRYE TLLKQRHVQL LGRSIDLNRL ITQRISAAMY
760 770 780 790 800
KSLDQAISRF ESEDLTSIVE LEWLLEINRL THRLLCKHMT LDSFDAMFRE
810 820 830 840 850
ANHNVSAPYG RITLHVFWEL NFDFLPNYCY NGSTNRFVRT AIPFTQEPQR
860 870 880 890 900
DKPANVQPYY LYGSKPLNIA YSHIYSSYRN FVGPPHFKTI CRLLGYQGIA
910 920 930 940 950
VVMEELLKIV KSLLQGTILQ YVKTLIEVMP KICRLPRHEY GSPGILEFFH
960 970 980 990 1000
HQLKDIIEYA ELKTDVFQSL REVGNAILFC LLIEQALSQE EVCDLLHAAP
1010 1020 1030 1040 1050
FQNILPRVYI KEGERLEVRM KRLEAKYAPL HLVPLIERLG TPQQIAIARE
1060 1070 1080 1090 1100
GDLLTKERLC CGLSMFEVIL TRIRSYLQDP IWRGPPPTNG VMHVDECVEF
1110 1120 1130 1140 1150
HRLWSAMQFV YCIPVGTNEF TAEQCFGDGL NWAGCSIIVL LGQQRRFDLF
1160 1170 1180 1190 1200
DFCYHLLKVQ RQDGKDEIIK NVPLKKMADR IRKYQILNNE VFAILNKYMK
1210 1220
SVETDSSTVE HVRCFQPPIH QSLATTC
Length:1,227
Mass (Da):142,577
Last modified:March 8, 2011 - v1
Checksum:i497CC1C4B258515C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008676 Genomic DNA. No translation available.
AC009185 Genomic DNA. No translation available.
AC016571 Genomic DNA. No translation available.
KF459628 Genomic DNA. No translation available.
KF510898 Genomic DNA. No translation available.
RefSeqiNP_001278650.1. NM_001291721.1.
UniGeneiHs.519702.

Genome annotation databases

EnsembliENST00000521420; ENSP00000430904; ENSG00000055163.
GeneIDi26999.
UCSCiuc011ddn.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008676 Genomic DNA. No translation available.
AC009185 Genomic DNA. No translation available.
AC016571 Genomic DNA. No translation available.
KF459628 Genomic DNA. No translation available.
KF510898 Genomic DNA. No translation available.
RefSeqiNP_001278650.1. NM_001291721.1.
UniGeneiHs.519702.

3D structure databases

ProteinModelPortaliE7EVJ5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000325817.

Proteomic databases

EPDiE7EVJ5.
PaxDbiE7EVJ5.
PeptideAtlasiE7EVJ5.
PRIDEiE7EVJ5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000521420; ENSP00000430904; ENSG00000055163.
GeneIDi26999.
UCSCiuc011ddn.3. human.

Organism-specific databases

CTDi26999.
HGNCiHGNC:13760. CYFIP2.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3534. Eukaryota.
ENOG410XPKW. LUCA.
GeneTreeiENSGT00500000044831.
TreeFamiTF312925.

Miscellaneous databases

ChiTaRSiCYFIP2. human.
GenomeRNAii26999.

Gene expression databases

BgeeiE7EVJ5.
ExpressionAtlasiE7EVJ5. baseline and differential.

Family and domain databases

InterProiIPR008081. Cytoplasmic_FMR1-int.
IPR009828. DUF1394.
[Graphical view]
PANTHERiPTHR12195. PTHR12195. 1 hit.
PfamiPF07159. DUF1394. 1 hit.
PF05994. FragX_IP. 1 hit.
[Graphical view]
PIRSFiPIRSF008153. FMR1_interacting. 1 hit.
PRINTSiPR01698. CYTOFMRPINTP.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 5."
    Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
    , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
    Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE7EVJ5_HUMAN
AccessioniPrimary (citable) accession number: E7EVJ5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 6, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.