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E7EVG6

- E7EVG6_HUMAN

UniProt

E7EVG6 - E7EVG6_HUMAN

Protein
Submitted name:

Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

Gene

PPRC1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (08 Mar 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. nucleic acid binding Source: InterPro
    2. nucleotide binding Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Peroxisome proliferator-activated receptor gamma coactivator-related protein 1Imported
    Gene namesi
    Name:PPRC1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 10

    Organism-specific databases

    HGNCiHGNC:30025. PPRC1.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: HPA

    Expressioni

    Gene expression databases

    ArrayExpressiE7EVG6.
    BgeeiE7EVG6.

    Structurei

    3D structure databases

    ProteinModelPortaliE7EVG6.
    SMRiE7EVG6. Positions 1279-1368.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK17963.

    Family and domain databases

    Gene3Di3.30.70.330. 1 hit.
    InterProiIPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view]
    PfamiPF00076. RRM_1. 1 hit.
    [Graphical view]
    SMARTiSM00360. RRM. 1 hit.
    [Graphical view]
    PROSITEiPS50102. RRM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E7EVG6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAARRGRRDG VAPPPSGGPG PDPGGGARGS GWGSRSQAPY GTLGAVSGGE     50
    QVLLHEEAGD SGFVSLSRLG PSLRDKDLEM EELMLQDETL LGTMQSYMDA 100
    SLISLIEDFG SLGESRLSLE DQNEVSLLTA LTEILDNADS ENLSPFDSIP 150
    DSELLVSPRE GSSLHKLLTL SRTPPERDLI TPVDPLGPST GSSRGSGVEM 200
    SLPDPSWDFS PPSFLETSSP KLPSWRPPRS RPRWGQSPPP QQRSDGEEEE 250
    EVASFSGQIL AGELDNCVSS IPDFPMHLAC PEEEDKATAA EMAVPAAGDE 300
    SISSLSELVR AMHPYCLPNL THLASLEDEL QEQPDDLTLP EGCVVLEIVG 350
    QAATAGDDLE IPVVVRQVSP GPRPVLLDDS LETSSALQLL MPTLESETEA 400
    AVPKVTLCSE KEGLSLNSEE KLDSACLLKP REVVEPVVPK EPQNPPANAA 450
    PGSQRARKGR KKKSKEQPAA CVEGYARRLR SSSRGQSTVG TEVTSQVDNL 500
    QKQPQEELQK ESGPLQGKGK PRAWARAWAA ALENSSPKNL ERSAGQSSPA 550
    KEGPLDLYPK LADTIQTNPI PTHLSLVDSA QASPMPVDSV EADPTAVGPV 600
    LAGPVPVDPG LVDLASTSSE LVEPLPAEPV LINPVLADSA AVDPAVVPIS 650
    DNLPPVDAVP SGPAPVDLAL VDPVPNDLTP VDPVLVKSRP TDPRRGAVSS 700
    ALGGSAPQLL VESESLDPPK TIIPEVKEVV DSLKIESGTS ATTHEARPRP 750
    LSLSEYRRRR QQRQAETEER SPQPPTGKWP SLPETPTGLA DIPCLVIPPA 800
    PAKKTALQRS PETPLEICLV PVGPSPASPS PEPPVSKPVA SSPTEQVPSQ 850
    EMPLLARPSP PVQSVSPAVP TPPSMSAALP FPAGGLGMPP SLPPPPLQPP 900
    SLPLSMGPVL PDPFTHYAPL PSWPCYPHVS PSGYPCLPPP PTVPLVSGTP 950
    GAYAVPPTCS VPWAPPPAPV SPYSSTCTYG PLGWGPGPQH APFWSTVPPP 1000
    PLPPASIGRA VPQPKMESRG TPAGPPENVL PLSMAPPLSL GLPGHGAPQT 1050
    EPTKVEVKPV PASPHPKHKV SALVQSPQMK ALACVSAEGV TVEEPASERL 1100
    KPETQETRPR EKPPLPATKA VPTPRQSTVP KLPAVHPARL RKLSFLPTPR 1150
    TQGSEDVVQA FISEIGIEAS DLSSLLEQFE KSEAKKECPP PAPADSLAVG 1200
    NSGSSCSSSG RSRRCSSSSS SSSSSSSSSS SSSSSRSRSR SPSPRRRSDR 1250
    RRRYSSYRSH DHYQRQRVLQ KERAIEERRV VFIGKIPGRM TRSELKQRFS 1300
    VFGEIEECTI HFRVQGDNYG FVTYRYAEEA FAAIESGHKL RQADEQPFDL 1350
    CFGGRRQFCK RSYSDLDSNR EDFDPAPVKS KFDSLDFDTL LKQAQKNLRR 1400
    Length:1,400
    Mass (Da):149,191
    Last modified:March 8, 2011 - v1
    Checksum:iE56CC8412EFF8A6E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL500527 Genomic DNA. No translation available.
    RefSeqiNP_001275656.1. NM_001288727.1.
    UniGeneiHs.533551.

    Genome annotation databases

    EnsembliENST00000413464; ENSP00000399743; ENSG00000148840.
    GeneIDi23082.
    KEGGihsa:23082.
    UCSCiuc010qqj.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL500527 Genomic DNA. No translation available.
    RefSeqi NP_001275656.1. NM_001288727.1.
    UniGenei Hs.533551.

    3D structure databases

    ProteinModelPortali E7EVG6.
    SMRi E7EVG6. Positions 1279-1368.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000413464 ; ENSP00000399743 ; ENSG00000148840 .
    GeneIDi 23082.
    KEGGi hsa:23082.
    UCSCi uc010qqj.2. human.

    Organism-specific databases

    CTDi 23082.
    HGNCi HGNC:30025. PPRC1.
    GenAtlasi Search...

    Phylogenomic databases

    KOi K17963.

    Miscellaneous databases

    GenomeRNAii 23082.
    NextBioi 35500639.

    Gene expression databases

    ArrayExpressi E7EVG6.
    Bgeei E7EVG6.

    Family and domain databases

    Gene3Di 3.30.70.330. 1 hit.
    InterProi IPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view ]
    Pfami PF00076. RRM_1. 1 hit.
    [Graphical view ]
    SMARTi SM00360. RRM. 1 hit.
    [Graphical view ]
    PROSITEi PS50102. RRM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
      , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
      Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE7EVG6_HUMAN
    AccessioniPrimary (citable) accession number: E7EVG6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3