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Protein
Submitted name:

Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

Gene

PPRC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1Imported
Gene namesi
Name:PPRC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi

Organism-specific databases

EuPathDBiHostDB:ENSG00000148840.10
HGNCiHGNC:30025 PPRC1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000148840

PTM / Processingi

Proteomic databases

MaxQBiE7EVG6
PeptideAtlasiE7EVG6
PRIDEiE7EVG6

Expressioni

Gene expression databases

BgeeiENSG00000148840
ExpressionAtlasiE7EVG6 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiE7EVG6, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliE7EVG6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1279 – 1355RRMInterPro annotationAdd BLAST77

Phylogenomic databases

eggNOGiENOG410IK9Y Eukaryota
ENOG4111HH9 LUCA
GeneTreeiENSGT00530000063196

Family and domain databases

CDDicd12624 RRM_PRC, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR034605 PGC-1
IPR034597 PRC
IPR034834 PRC_RRM
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PANTHERiPTHR15528 PTHR15528, 2 hits
PTHR15528:SF5 PTHR15528:SF5, 2 hits
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequencei

Sequence statusi: Complete.

E7EVG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARRGRRDG VAPPPSGGPG PDPGGGARGS GWGSRSQAPY GTLGAVSGGE
60 70 80 90 100
QVLLHEEAGD SGFVSLSRLG PSLRDKDLEM EELMLQDETL LGTMQSYMDA
110 120 130 140 150
SLISLIEDFG SLGESRLSLE DQNEVSLLTA LTEILDNADS ENLSPFDSIP
160 170 180 190 200
DSELLVSPRE GSSLHKLLTL SRTPPERDLI TPVDPLGPST GSSRGSGVEM
210 220 230 240 250
SLPDPSWDFS PPSFLETSSP KLPSWRPPRS RPRWGQSPPP QQRSDGEEEE
260 270 280 290 300
EVASFSGQIL AGELDNCVSS IPDFPMHLAC PEEEDKATAA EMAVPAAGDE
310 320 330 340 350
SISSLSELVR AMHPYCLPNL THLASLEDEL QEQPDDLTLP EGCVVLEIVG
360 370 380 390 400
QAATAGDDLE IPVVVRQVSP GPRPVLLDDS LETSSALQLL MPTLESETEA
410 420 430 440 450
AVPKVTLCSE KEGLSLNSEE KLDSACLLKP REVVEPVVPK EPQNPPANAA
460 470 480 490 500
PGSQRARKGR KKKSKEQPAA CVEGYARRLR SSSRGQSTVG TEVTSQVDNL
510 520 530 540 550
QKQPQEELQK ESGPLQGKGK PRAWARAWAA ALENSSPKNL ERSAGQSSPA
560 570 580 590 600
KEGPLDLYPK LADTIQTNPI PTHLSLVDSA QASPMPVDSV EADPTAVGPV
610 620 630 640 650
LAGPVPVDPG LVDLASTSSE LVEPLPAEPV LINPVLADSA AVDPAVVPIS
660 670 680 690 700
DNLPPVDAVP SGPAPVDLAL VDPVPNDLTP VDPVLVKSRP TDPRRGAVSS
710 720 730 740 750
ALGGSAPQLL VESESLDPPK TIIPEVKEVV DSLKIESGTS ATTHEARPRP
760 770 780 790 800
LSLSEYRRRR QQRQAETEER SPQPPTGKWP SLPETPTGLA DIPCLVIPPA
810 820 830 840 850
PAKKTALQRS PETPLEICLV PVGPSPASPS PEPPVSKPVA SSPTEQVPSQ
860 870 880 890 900
EMPLLARPSP PVQSVSPAVP TPPSMSAALP FPAGGLGMPP SLPPPPLQPP
910 920 930 940 950
SLPLSMGPVL PDPFTHYAPL PSWPCYPHVS PSGYPCLPPP PTVPLVSGTP
960 970 980 990 1000
GAYAVPPTCS VPWAPPPAPV SPYSSTCTYG PLGWGPGPQH APFWSTVPPP
1010 1020 1030 1040 1050
PLPPASIGRA VPQPKMESRG TPAGPPENVL PLSMAPPLSL GLPGHGAPQT
1060 1070 1080 1090 1100
EPTKVEVKPV PASPHPKHKV SALVQSPQMK ALACVSAEGV TVEEPASERL
1110 1120 1130 1140 1150
KPETQETRPR EKPPLPATKA VPTPRQSTVP KLPAVHPARL RKLSFLPTPR
1160 1170 1180 1190 1200
TQGSEDVVQA FISEIGIEAS DLSSLLEQFE KSEAKKECPP PAPADSLAVG
1210 1220 1230 1240 1250
NSGSSCSSSG RSRRCSSSSS SSSSSSSSSS SSSSSRSRSR SPSPRRRSDR
1260 1270 1280 1290 1300
RRRYSSYRSH DHYQRQRVLQ KERAIEERRV VFIGKIPGRM TRSELKQRFS
1310 1320 1330 1340 1350
VFGEIEECTI HFRVQGDNYG FVTYRYAEEA FAAIESGHKL RQADEQPFDL
1360 1370 1380 1390 1400
CFGGRRQFCK RSYSDLDSNR EDFDPAPVKS KFDSLDFDTL LKQAQKNLRR
Length:1,400
Mass (Da):149,191
Last modified:March 8, 2011 - v1
Checksum:iE56CC8412EFF8A6E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL500527 Genomic DNA No translation available.
RefSeqiNP_001275656.1, NM_001288727.1
UniGeneiHs.533551

Genome annotation databases

EnsembliENST00000413464; ENSP00000399743; ENSG00000148840
GeneIDi23082
UCSCiuc010qqj.4 human

Entry informationi

Entry nameiE7EVG6_HUMAN
AccessioniPrimary (citable) accession number: E7EVG6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: April 25, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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