ID   E7EVC2_HUMAN            Unreviewed;       147 AA.
AC   E7EVC2;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 3.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=GIT ArfGAP 1 {ECO:0000313|Ensembl:ENSP00000334125.7};
DE   Flags: Fragment;
GN   Name=GIT1 {ECO:0000313|Ensembl:ENSP00000334125.7};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000334125.7, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000334125.7, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA   Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA   Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA   LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA   Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA   Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA   Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT   human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000334125.7}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC104564; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; E7EVC2; -.
DR   MaxQB; E7EVC2; -.
DR   PeptideAtlas; E7EVC2; -.
DR   ProteomicsDB; 18607; -.
DR   Antibodypedia; 1365; 581 antibodies from 36 providers.
DR   Ensembl; ENST00000335356.7; ENSP00000334125.7; ENSG00000108262.16.
DR   UCSC; uc060djy.1; human.
DR   HGNC; HGNC:4272; GIT1.
DR   VEuPathDB; HostDB:ENSG00000108262; -.
DR   GeneTree; ENSGT00940000159604; -.
DR   HOGENOM; CLU_1772310_0_0_1; -.
DR   ChiTaRS; GIT1; human.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000108262; Expressed in right frontal lobe and 205 other cell types or tissues.
DR   ExpressionAtlas; E7EVC2; baseline and differential.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   REGION          81..103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        87..103
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         147
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000334125.7"
SQ   SEQUENCE   147 AA;  15374 MW;  43A7C9EAD1897040 CRC64;
     MSRKGPRAEV CADCSAPGVC WCVTSAAACT GAWDATSPLS STFATAPGLP RCCRWCTRLP
     ATGPTPSGST PCWTPHKCRA AGVKPTPKTK STPSSQSSSG PSTRCWHLCT SFPAGTMMES
     PPKTSASNYT RACGQATWRH VCACSPW
//