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Protein
Submitted name:

Importin-5

Gene

IPO5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Importin-5Imported
Gene namesi
Name:IPO5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

HGNCiHGNC:6402. IPO5.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000065150.

PTM / Processingi

Proteomic databases

MaxQBiE7EV12.
PaxDbiE7EV12.
PeptideAtlasiE7EV12.
PRIDEiE7EV12.

Expressioni

Gene expression databases

BgeeiENSG00000065150.
ExpressionAtlasiE7EV12. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000261574.

Structurei

3D structure databases

ProteinModelPortaliE7EV12.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 117Importin N-terminalInterPro annotationAdd BLAST55

Phylogenomic databases

eggNOGiKOG2171. Eukaryota.
ENOG410XQAJ. LUCA.
GeneTreeiENSGT00550000074773.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR001494. Importin-beta_N.
[Graphical view]
PfamiPF03810. IBN_N. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50166. IMPORTIN_B_NT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E7EV12-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEDQVGKLE ATENTISAMA AAAAEQQQFY LLLGNLLSPD NVVRKQAEET
60 70 80 90 100
YENIPGQSKI TFLLQAIRNT TAAEEARQMA AVLLRRLLSS AFDEVYPALP
110 120 130 140
SDVQTAIKSE LLMIIQMETQ SSMRKKVCDI AAELARNLIG VY
Length:142
Mass (Da):15,676
Last modified:March 8, 2011 - v1
Checksum:i5D431E318D25C685
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei142Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137120 Genomic DNA. No translation available.
AL356580 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000460070; ENSP00000420284; ENSG00000065150.
UCSCiuc058xvl.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137120 Genomic DNA. No translation available.
AL356580 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE7EV12.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000261574.

Proteomic databases

MaxQBiE7EV12.
PaxDbiE7EV12.
PeptideAtlasiE7EV12.
PRIDEiE7EV12.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000460070; ENSP00000420284; ENSG00000065150.
UCSCiuc058xvl.1. human.

Organism-specific databases

HGNCiHGNC:6402. IPO5.
OpenTargetsiENSG00000065150.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2171. Eukaryota.
ENOG410XQAJ. LUCA.
GeneTreeiENSGT00550000074773.

Miscellaneous databases

ChiTaRSiIPO5. human.

Gene expression databases

BgeeiENSG00000065150.
ExpressionAtlasiE7EV12. baseline and differential.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR001494. Importin-beta_N.
[Graphical view]
PfamiPF03810. IBN_N. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50166. IMPORTIN_B_NT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE7EV12_HUMAN
AccessioniPrimary (citable) accession number: E7EV12
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: November 30, 2016
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.