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E7EUK8

- E7EUK8_HUMAN

UniProt

E7EUK8 - E7EUK8_HUMAN

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Protein
Submitted name:

Cyclin-dependent kinase 14

Gene

CDK14

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. protein serine/threonine kinase activity Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

SignaLinkiE7EUK8.

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin-dependent kinase 14Imported
Gene namesi
Name:CDK14Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:8883. CDK14.

Expressioni

Gene expression databases

BgeeiE7EUK8.
ExpressionAtlasiE7EUK8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE7EUK8.
SMRiE7EUK8. Positions 31-311.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00600000083998.
KOiK08821.
OrthoDBiEOG7966H8.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E7EUK8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLALTLRPPP LAKSHLKLGG TPAPARVNGK LVALKVIRLQ EEEGTPFTAI
60 70 80 90 100
REASLLKGLK HANIVLLHDI IHTKETLTLV FEYVHTDLCQ YMDKHPGGLH
110 120 130 140 150
PDNVKLFLFQ LLRGLSYIHQ RYILHRDLKP QNLLISDTGE LKLADFGLAR
160 170 180 190 200
AKSVPSHTYS NEVVTLWYRP PDVLLGSTEY STCLDMWGVG CIFVEMIQGV
210 220 230 240 250
AAFPGMKDIQ DQLERIFLVL GTPNEDTWPG VHSLPHFKPE RFTLYSSKNL
260 270 280 290 300
RQAWNKLSYV NHAEDLASKL LQCSPKNRLS AQAALSHEYF SDLPPRLWEL
310 320 330 340
TDMSSIFTVP NVRLQPEAGE SMRAFGKNNS YGKSLSNSKH
Length:340
Mass (Da):38,314
Last modified:March 8, 2011 - v1
Checksum:iB66E0C52EBAE2243
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000057 Genomic DNA. No translation available.
AC000059 Genomic DNA. No translation available.
AC002065 Genomic DNA. No translation available.
AC002456 Genomic DNA. No translation available.
AC002458 Genomic DNA. No translation available.
AC003076 Genomic DNA. No translation available.
AC006036 Genomic DNA. No translation available.
AC017036 Genomic DNA. No translation available.
AC084381 Genomic DNA. No translation available.
KF458503 Genomic DNA. No translation available.
KF458505 Genomic DNA. No translation available.
KF458507 Genomic DNA. No translation available.
KF510291 Genomic DNA. No translation available.
RefSeqiNP_001274066.1. NM_001287137.1.
UniGeneiHs.258576.
Hs.430742.

Genome annotation databases

EnsembliENST00000436577; ENSP00000398936; ENSG00000058091.
GeneIDi5218.
KEGGihsa:5218.
UCSCiuc011khl.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000057 Genomic DNA. No translation available.
AC000059 Genomic DNA. No translation available.
AC002065 Genomic DNA. No translation available.
AC002456 Genomic DNA. No translation available.
AC002458 Genomic DNA. No translation available.
AC003076 Genomic DNA. No translation available.
AC006036 Genomic DNA. No translation available.
AC017036 Genomic DNA. No translation available.
AC084381 Genomic DNA. No translation available.
KF458503 Genomic DNA. No translation available.
KF458505 Genomic DNA. No translation available.
KF458507 Genomic DNA. No translation available.
KF510291 Genomic DNA. No translation available.
RefSeqi NP_001274066.1. NM_001287137.1.
UniGenei Hs.258576.
Hs.430742.

3D structure databases

ProteinModelPortali E7EUK8.
SMRi E7EUK8. Positions 31-311.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000436577 ; ENSP00000398936 ; ENSG00000058091 .
GeneIDi 5218.
KEGGi hsa:5218.
UCSCi uc011khl.1. human.

Organism-specific databases

CTDi 5218.
HGNCi HGNC:8883. CDK14.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00600000083998.
KOi K08821.
OrthoDBi EOG7966H8.

Enzyme and pathway databases

SignaLinki E7EUK8.

Miscellaneous databases

ChiTaRSi CDK14. human.
GenomeRNAii 5218.
NextBioi 35500504.

Gene expression databases

Bgeei E7EUK8.
ExpressionAtlasi E7EUK8. baseline and differential.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE7EUK8_HUMAN
AccessioniPrimary (citable) accession number: E7EUK8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: November 26, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3