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Protein
Submitted name:

Cyclin-dependent kinase 14

Gene

CDK14

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. protein serine/threonine kinase activity Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

SignaLinkiE7EUK8.

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin-dependent kinase 14Imported
Gene namesi
Name:CDK14Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:8883. CDK14.

Expressioni

Gene expression databases

BgeeiE7EUK8.
ExpressionAtlasiE7EUK8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE7EUK8.
SMRiE7EUK8. Positions 31-311.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00780000121869.
KOiK08821.
OrthoDBiEOG7966H8.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E7EUK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLALTLRPPP LAKSHLKLGG TPAPARVNGK LVALKVIRLQ EEEGTPFTAI
60 70 80 90 100
REASLLKGLK HANIVLLHDI IHTKETLTLV FEYVHTDLCQ YMDKHPGGLH
110 120 130 140 150
PDNVKLFLFQ LLRGLSYIHQ RYILHRDLKP QNLLISDTGE LKLADFGLAR
160 170 180 190 200
AKSVPSHTYS NEVVTLWYRP PDVLLGSTEY STCLDMWGVG CIFVEMIQGV
210 220 230 240 250
AAFPGMKDIQ DQLERIFLVL GTPNEDTWPG VHSLPHFKPE RFTLYSSKNL
260 270 280 290 300
RQAWNKLSYV NHAEDLASKL LQCSPKNRLS AQAALSHEYF SDLPPRLWEL
310 320 330 340
TDMSSIFTVP NVRLQPEAGE SMRAFGKNNS YGKSLSNSKH
Length:340
Mass (Da):38,314
Last modified:March 8, 2011 - v1
Checksum:iB66E0C52EBAE2243
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000057 Genomic DNA. No translation available.
AC000059 Genomic DNA. No translation available.
AC002065 Genomic DNA. No translation available.
AC002456 Genomic DNA. No translation available.
AC002458 Genomic DNA. No translation available.
AC003076 Genomic DNA. No translation available.
AC006036 Genomic DNA. No translation available.
AC017036 Genomic DNA. No translation available.
AC084381 Genomic DNA. No translation available.
KF458503 Genomic DNA. No translation available.
KF458505 Genomic DNA. No translation available.
KF458507 Genomic DNA. No translation available.
KF510291 Genomic DNA. No translation available.
RefSeqiNP_001274066.1. NM_001287137.1.
UniGeneiHs.258576.
Hs.430742.

Genome annotation databases

EnsembliENST00000436577; ENSP00000398936; ENSG00000058091.
GeneIDi5218.
KEGGihsa:5218.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000057 Genomic DNA. No translation available.
AC000059 Genomic DNA. No translation available.
AC002065 Genomic DNA. No translation available.
AC002456 Genomic DNA. No translation available.
AC002458 Genomic DNA. No translation available.
AC003076 Genomic DNA. No translation available.
AC006036 Genomic DNA. No translation available.
AC017036 Genomic DNA. No translation available.
AC084381 Genomic DNA. No translation available.
KF458503 Genomic DNA. No translation available.
KF458505 Genomic DNA. No translation available.
KF458507 Genomic DNA. No translation available.
KF510291 Genomic DNA. No translation available.
RefSeqiNP_001274066.1. NM_001287137.1.
UniGeneiHs.258576.
Hs.430742.

3D structure databases

ProteinModelPortaliE7EUK8.
SMRiE7EUK8. Positions 31-311.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000436577; ENSP00000398936; ENSG00000058091.
GeneIDi5218.
KEGGihsa:5218.

Organism-specific databases

CTDi5218.
HGNCiHGNC:8883. CDK14.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00780000121869.
KOiK08821.
OrthoDBiEOG7966H8.

Enzyme and pathway databases

SignaLinkiE7EUK8.

Miscellaneous databases

ChiTaRSiCDK14. human.
GenomeRNAii5218.
NextBioi35500504.

Gene expression databases

BgeeiE7EUK8.
ExpressionAtlasiE7EUK8. baseline and differential.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE7EUK8_HUMAN
AccessioniPrimary (citable) accession number: E7EUK8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: March 4, 2015
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationMaxQB annotation, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.