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E7EUK6 (E7EUK6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length438 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the AB hydrolase superfamily. Lipase family. RuleBase RU004262

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000395002

Ontologies

Keywords
   Cellular componentSecreted SAAS SAAS013818
   Molecular functionHydrolase RuleBase RU004263
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processlipid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functiontriglyceride lipase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1071Nucleophile By similarity PIRSR PIRSR000865-1
Active site1331Charge relay system By similarity PIRSR PIRSR000865-1
Active site2181Charge relay system By similarity PIRSR PIRSR000865-1

Sequences

Sequence LengthMass (Da)Tools
E7EUK6 [UniParc].

Last modified March 8, 2011. Version 1.
Checksum: A58A6858E271BEA4

FASTA43849,026
        10         20         30         40         50         60 
MDTSPLCFSI LLVLCIFIQS SALGQSLKPE PFGRRAQAVE TNKTLHEMKT RFLLFGETNQ 

        70         80         90        100        110        120 
GCQIRINHPD TLQECGFNSS LPLVMIIHGW SESVQLSRSH VHLIGYSLGA HVSGFAGSSI 

       130        140        150        160        170        180 
GGTHKIGRIT GLDAAGPLFE GSAPSNRLSP DDANFVDAIH TFTREHMGLS VGIKQPIGHY 

       190        200        210        220        230        240 
DFYPNGGSFQ PGCHFLELYR HIAQHGFNAI TQTIKCSHER SVHLFIDSLL HAGTQSMAYP 

       250        260        270        280        290        300 
CGDMNSFSQG LCLSCKKGRC NTLGYHVRQE PRSKSKRLFL VTRAQSPFKV YHYQFKIQFI 

       310        320        330        340        350        360 
NQTETPIQTT FTMSLLGTKE KMQKIPITLG KGIASNKTYS FLITLDVDIG ELIMIKFKWE 

       370        380        390        400        410        420 
NSAVWANVWD TVQTIIPWST GPRHSGLVLK TIRVKAGETQ QRMTFCSENT DDLLLRPTQE 

       430 
KIFVKCEIKS KTSKRKIR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC018904 Genomic DNA. No translation available.
AC084781 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalE7EUK6.
SMRE7EUK6. Positions 86-410.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000433326; ENSP00000395002; ENSG00000166035.
UCSCuc010ugy.2. human.

Organism-specific databases

HGNCHGNC:6619. LIPC.
GenAtlasSearch...

Gene expression databases

ArrayExpressE7EUK6.
BgeeE7EUK6.

Family and domain databases

Gene3D2.60.60.20. 1 hit.
3.40.50.1820. 2 hits.
InterProIPR029058. AB_hydrolase.
IPR000734. Lipase.
IPR002333. Lipase_hep.
IPR008976. Lipase_LipOase.
IPR013818. Lipase_N.
IPR016272. Lipoprotein_lipase_LIPH.
IPR001024. PLAT/LH2_dom.
[Graphical view]
PANTHERPTHR11610. PTHR11610. 1 hit.
PTHR11610:SF2. PTHR11610:SF2. 1 hit.
PfamPF00151. Lipase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PIRSFPIRSF000865. Lipoprotein_lipase_LIPH. 1 hit.
PRINTSPR00824. HEPLIPASE.
PR00821. TAGLIPASE.
SMARTSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMSSF49723. SSF49723. 1 hit.
SSF53474. SSF53474. 1 hit.
PROSITEPS50095. PLAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSLIPC. human.
NextBio35500503.

Entry information

Entry nameE7EUK6_HUMAN
AccessionPrimary (citable) accession number: E7EUK6
Entry history
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 9, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.