Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

E7EUJ1 (E7EUJ1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length499 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the AB hydrolase superfamily. Lipase family. RuleBase RU004262

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000395569

Ontologies

Keywords
   Cellular componentSecreted SAAS SAAS013818
   Molecular functionHydrolase RuleBase RU004263
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processlipid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functiontriglyceride lipase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1681Nucleophile By similarity PIRSR PIRSR000865-1
Active site1941Charge relay system By similarity PIRSR PIRSR000865-1
Active site2791Charge relay system By similarity PIRSR PIRSR000865-1

Sequences

Sequence LengthMass (Da)Tools
E7EUJ1 [UniParc].

Last modified March 8, 2011. Version 1.
Checksum: C5FED21BD5574072

FASTA49955,617
        10         20         30         40         50         60 
MDTSPLCFSI LLVLCIFIQS SALGQSLKPE PFGRRAQAVE TNKTLHEMKT RFLLFGETNQ 

        70         80         90        100        110        120 
GCQIRINHPD TLQECGFNSS LPLVMIIHGW SVDGVLENWI WQMVAALKSQ PAQPVNVGLV 

       130        140        150        160        170        180 
DWITLAHDHY TIAVRNTRLV GKEVAALLRW LEESVQLSRS HVHLIGYSLG AHVSGFAGSS 

       190        200        210        220        230        240 
IGGTHKIGRI TGLDAAGPLF EGSAPSNRLS PDDANFVDAI HTFTREHMGL SVGIKQPIGH 

       250        260        270        280        290        300 
YDFYPNGGSF QPGCHFLELY RHIAQHGFNA ITQTIKCSHE RSVHLFIDSL LHAGTQSMAY 

       310        320        330        340        350        360 
PCGDMNSFSQ GLCLSCKKGR CNTLGYHVRQ EPRSKSKRLF LVTRAQSPFK VYHYQFKIQF 

       370        380        390        400        410        420 
INQTETPIQT TFTMSLLGTK EKMQKIPITL GKGIASNKTY SFLITLDVDI GELIMIKFKW 

       430        440        450        460        470        480 
ENSAVWANVW DTVQTIIPWS TGPRHSGLVL KTIRVKAGET QQRSPNRINL GRLNCSLLFC 

       490 
TELFSHDSLA HWSSAASEL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC018904 Genomic DNA. No translation available.
AC084781 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalE7EUJ1.
SMRE7EUJ1. Positions 47-425.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000414170; ENSP00000395569; ENSG00000166035.
KEGGhsa:3990.

Organism-specific databases

HGNCHGNC:6619. LIPC.
GenAtlasSearch...

Phylogenomic databases

OMACHFLELY.
PhylomeDBE7EUJ1.

Gene expression databases

ArrayExpressE7EUJ1.
BgeeE7EUJ1.

Family and domain databases

Gene3D2.60.60.20. 1 hit.
3.40.50.1820. 1 hit.
InterProIPR029058. AB_hydrolase.
IPR000734. Lipase.
IPR002333. Lipase_hep.
IPR008976. Lipase_LipOase.
IPR013818. Lipase_N.
IPR016272. Lipoprotein_lipase_LIPH.
IPR001024. PLAT/LH2_dom.
[Graphical view]
PANTHERPTHR11610. PTHR11610. 1 hit.
PTHR11610:SF2. PTHR11610:SF2. 1 hit.
PfamPF00151. Lipase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PIRSFPIRSF000865. Lipoprotein_lipase_LIPH. 1 hit.
PRINTSPR00824. HEPLIPASE.
PR00821. TAGLIPASE.
SMARTSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMSSF49723. SSF49723. 1 hit.
SSF53474. SSF53474. 1 hit.
PROSITEPS50095. PLAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSLIPC. human.
GenomeRNAi3990.
NextBio35500499.

Entry information

Entry nameE7EUJ1_HUMAN
AccessionPrimary (citable) accession number: E7EUJ1
Entry history
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 9, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.