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Protein
Submitted name:

Histone deacetylase 11

Gene

HDAC11

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Histone deacetylase 11Imported
Gene namesi
Name:HDAC11Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:19086. HDAC11.

PTM / Processingi

Proteomic databases

PaxDbiE7ETT9.
PeptideAtlasiE7ETT9.

Expressioni

Gene expression databases

BgeeiENSG00000163517.
ExpressionAtlasiE7ETT9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000295757.

Structurei

3D structure databases

ProteinModelPortaliE7ETT9.
SMRiE7ETT9. Positions 13-305.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 288282Hist_deacetylInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1344. Eukaryota.
COG0123. LUCA.
GeneTreeiENSGT00390000003411.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PRINTSiPR01270. HDASUPER.

Sequencei

Sequence statusi: Complete.

E7ETT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLEKLHPFD AGKWGKVINF LKEEKLLSDS MLVEAREASE EDLLVVHTRR
60 70 80 90 100
YLNELKWSFA VATITEIPPV IFLPNFLVQR KVLRPLRTQT GGTIMAGKLA
110 120 130 140 150
VERGWAINVG GGFHHCSSDR GGGFCAYADI TLAIKFLFER VEGISRATII
160 170 180 190 200
DLDAHQGNGH ERDFMDDKRV YIMDVYNRHI YPGDRFAKQA IRRKVELEWG
210 220 230 240 250
TEDDEYLDKV ERNIKKSLQE HLPDVVVYNA GTDILEGDRL GGLSISPAGI
260 270 280 290 300
VKRDELVFRM VRGRRVPILM VTSGGYQKRT ARIIADSILN LFGLGLIGPE
310
SPSVSAQNSD TPLLPPAVP
Length:319
Mass (Da):35,709
Last modified:March 8, 2011 - v1
Checksum:i74F22907DB3626F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC027124 Genomic DNA. No translation available.
RefSeqiXP_005265548.1. XM_005265491.1.
XP_011532433.1. XM_011534131.1.
UniGeneiHs.744132.

Genome annotation databases

EnsembliENST00000437379; ENSP00000395188; ENSG00000163517.
GeneIDi79885.
UCSCiuc062gxo.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC027124 Genomic DNA. No translation available.
RefSeqiXP_005265548.1. XM_005265491.1.
XP_011532433.1. XM_011534131.1.
UniGeneiHs.744132.

3D structure databases

ProteinModelPortaliE7ETT9.
SMRiE7ETT9. Positions 13-305.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000295757.

Proteomic databases

PaxDbiE7ETT9.
PeptideAtlasiE7ETT9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000437379; ENSP00000395188; ENSG00000163517.
GeneIDi79885.
UCSCiuc062gxo.1. human.

Organism-specific databases

CTDi79885.
HGNCiHGNC:19086. HDAC11.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1344. Eukaryota.
COG0123. LUCA.
GeneTreeiENSGT00390000003411.

Miscellaneous databases

ChiTaRSiHDAC11. human.
GenomeRNAii79885.

Gene expression databases

BgeeiENSG00000163517.
ExpressionAtlasiE7ETT9. baseline and differential.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PRINTSiPR01270. HDASUPER.
ProtoNetiSearch...

Entry informationi

Entry nameiE7ETT9_HUMAN
AccessioniPrimary (citable) accession number: E7ETT9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: September 7, 2016
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.