E7ETD3 (E7ETD3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ATP-binding cassette sub-family A member 5 Ensembl ENSP00000376444

Gene names

Name:

ABCA5 Ensembl ENSP00000376444

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000376444

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1643 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Belongs to the ABC transporter superfamily. RuleBase RU000684
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000376444

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU003299 Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E7ETD3 [UniParc]. Last modified March 8, 2011. Version 1. Checksum: B4C860FF7AA6CF6A	FASTA	1,643	186,579
	10 20 30 40 50 60 MSTAIREVGV WRQTRTLLLK NYLIKCRTKK SSVQEILFPL FFLFWLILIS MMHPNKKYEE 70 80 90 100 110 120 VPNIELNPMD KFTLSNLILG YTPVTNITSS IMQKVSTDHL PDVIITEEYT NEKEMLTSSL 130 140 150 160 170 180 SKPSNFVGVV FKDSMSYELR FFPDMIPVSS IYMDSRAGCS KSCEAAQYWS SGFTVLQASI 190 200 210 220 230 240 DAAIIQLKTN VSLWKELEST KAVIMGETAV VEIDTFPRGV ILIYLVIAFS PFGYFLAIHI 250 260 270 280 290 300 VAEKEKKIKE FLKIMGLHDT AFWLSWVLLY TSLIFLMSLL MAVIATASLL FPQSSSIVIF 310 320 330 340 350 360 LLFFLYGLSS VFFALMLTPL FKKSKHVGIV EFFVTVAFGF IGLMIILIES FPKSLVWLFS 370 380 390 400 410 420 PFCHCTFVIG IAQVMHLEDF NEGASFSNLT AGPYPLIITI IMLTLNSIFY VLLAVYLDQV 430 440 450 460 470 480 IPGEFGLRRS SLYFLKPSYW SKSKRNYEEL SEGNVNGNIS FSEIIEPVSS EFVGKEAIRI 490 500 510 520 530 540 SGIQKTYRKK GENVEALRNL SFDIYEGQIT ALLGHSGTGK STLMNILCGL CPPSDGFASI 550 560 570 580 590 600 YGHRVSEIDE MFEARKMIGI CPQLDIHFDV LTVEENLSIL ASIKGIPANN IIQEVQKVLL 610 620 630 640 650 660 DLDMQTIKDN QAKKLSGGQK RKLSLGIAVL GNPKILLLDE PTAGMDPCSR HIVWNLLKYR 670 680 690 700 710 720 KANRVTVFST HFMDEADILA DRKAVISQGM LKCVGSSMFL KSKWGIGYRL SMYIDKYCAT 730 740 750 760 770 780 ESLSSLVKQH IPGATLLQQN DQQLVYSLPF KDMDKFSGLF SALDSHSNLG VISYGVSMTT 790 800 810 820 830 840 LEDVFLKLEV EAEIDQADYS VFTQQPLEEE MDSKSFDEME QSLLILSETK AALVSTMSLW 850 860 870 880 890 900 KQQMYTIAKF HFFTLKRESK SVRSVLLLLL IFFTVQIFMF LVHHSFKNAV VPIKLVPDLY 910 920 930 940 950 960 FLKPGDKPHK YKTSLLLQNS AADSDISDLI SFFTSQNIMV TMINDSDYVS VAPHSAALNV 970 980 990 1000 1010 1020 MHSEKDYVFA AVFNSTMVYS LPILVNIISN YYLYHLNVTE TIQIWSTPFF QEITDIVFKI 1030 1040 1050 1060 1070 1080 ELYFQAALLG IIVTAMPPYF AMENAENHKI KAYTQLKLSG LLPSAYWIGQ AVVDIPLFFI 1090 1100 1110 1120 1130 1140 ILILMLGSLL AFHYGLYFYT VKFLAVVFCL IGYVPSVILF TYIASFTFKK ILNTKEFWSF 1150 1160 1170 1180 1190 1200 IYSVAALACI AITEITFFMG YTIATILHYA FCIIIPIYPL LGCLISFIKI SWKNVRKNVD 1210 1220 1230 1240 1250 1260 TYNPWDRLSV AVISPYLQCV LWIFLLQYYE KKYGGRSIRK DPFFRNLSTK SKNRKLPEPP 1270 1280 1290 1300 1310 1320 DNEDEDEDVK AERLKVKELM GCQCCEEKPS IMVSNLHKEY DDKKDFLLSR KVKKVATKYI 1330 1340 1350 1360 1370 1380 SFCVKKGEIL GLLGPNGAGK STIINILVGD IEPTSGQVFL GDYSSETSED DDSLKCMGYC 1390 1400 1410 1420 1430 1440 PQINPLWPDT TLQEHFEIYG AVKGMSASDM KEVISRITHA LDLKEHLQKT VKKLPAGIKR 1450 1460 1470 1480 1490 1500 KLCFALSMLG NPQITLLDEP STGMDPKAKQ HMWRAIRTAF KNRKRAAILT THYMEEAEAV 1510 1520 1530 1540 1550 1560 CDRVAIMVSG QLRCIGTVQH LKSKFGKGYF LEIKLKDWIE NLEVDRLQRE IQYIFPNASR 1570 1580 1590 1600 1610 1620 QESFSSILAY KIPKEDVQSL SQSFFKLEEA KHAFAIEEYS FSQATLEQVF VELTKEQEEE 1630 1640 DNSCGTLNST LWWERTQEDR VVF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L. , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C. Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC005495 Genomic DNA. No translation available. AC115085 Genomic DNA. No translation available.
IPI	IPI00874173.
3D structure databases
ProteinModelPortal	E7ETD3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000392677; ENSP00000376444; ENSG00000154265.
Organism-specific databases
HGNC	HGNC:35. ABCA5.
GenAtlas	Search...
Phylogenomic databases
OMA	DGFASIY.
Gene expression databases
ArrayExpress	E7ETD3.
Bgee	E7ETD3.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR026082. ABC_A. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. [Graphical view]
PANTHER	PTHR19229. PTHR19229. 1 hit.
Pfam	PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 2 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ABCA5. human.
NextBio	35500319.

Entry information

Entry name

E7ETD3_HUMAN

Accession

Primary (citable) accession number: E7ETD3

Entry history

Integrated into UniProtKB/TrEMBL:	March 8, 2011
Last sequence update:	March 8, 2011
Last modified:	April 3, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.