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Protein
Submitted name:

Neurexin-1-beta

Gene

NRXN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Neurexin-1-betaImported
Gene namesi
Name:NRXN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:8008. NRXN1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei398 – 418HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000179915.

PTM / Processingi

Proteomic databases

PRIDEiE7ETA5.

Expressioni

Gene expression databases

BgeeiENSG00000179915.
ExpressionAtlasiE7ETA5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE7ETA5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini91 – 289LAM_G_DOMAINInterPro annotationAdd BLAST199

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118991.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR001791. Laminin_G.
IPR029824. Neurexin-1.
IPR003585. Neurexin-like.
IPR027789. Syndecan/Neurexin_dom.
[Graphical view]
PANTHERiPTHR10127:SF565. PTHR10127:SF565. 2 hits.
PfamiPF02210. Laminin_G_2. 1 hit.
PF01034. Syndecan. 1 hit.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
SM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 2 hits.
PROSITEiPS50025. LAM_G_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E7ETA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYQRMLRCGA ELGSPGGGGG GGGGGGAGGR LALLWIVPLT LSGLLGVAWG
60 70 80 90 100
ASSLGAHHIH HFHGSSKHHS VPIAIYRSPA SLRGGHAGTT YIFSKGGGQI
110 120 130 140 150
TYKWPPNDRP STRADRLAIG FSTVQKEAVL VRVDSSSGLG DYLELHIHQG
160 170 180 190 200
KIGVKFNVGT DDIAIEESNA IINDGKYHVV RFTRSGGNAT LQVDSWPVIE
210 220 230 240 250
RYPAGNNDNE RLAIARQRIP YRLGRVVDEW LLDKGRQLTI FNSQATIIIG
260 270 280 290 300
GKEQGQPFQG QLSGLYYNGL KVLNMAAEND ANIAIVGNVR LVGEVPSSMT
310 320 330 340 350
TESTATAMQS EMSTSIMETT TTLATSTARR GKPPTKEPIS QTTDDILVAS
360 370 380 390 400
AECPSDDEDI DPCEPSSGGL ANPTRAGGRE PYPGSAEVIR ESSSTTGMVV
410 420 430 440 450
GIVAAAALCI LILLYAMYKY RNRDEGSYHV DESRNYISNS AQSNGAVVKE
460 470
KQPSSAKSSN KNKKNKDKEY YV
Length:472
Mass (Da):50,424
Last modified:May 27, 2015 - v2
Checksum:iC86516C0EB7A2D01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007462 Genomic DNA. No translation available.
AC007560 Genomic DNA. No translation available.
AC007680 Genomic DNA. No translation available.
AC007682 Genomic DNA. No translation available.
AC009234 Genomic DNA. No translation available.
AC010721 Genomic DNA. No translation available.
AC068715 Genomic DNA. No translation available.
AC068725 Genomic DNA. No translation available.
AC069550 Genomic DNA. No translation available.
AC078994 Genomic DNA. No translation available.
RefSeqiNP_001317021.1. NM_001330092.1.
UniGeneiHs.637685.

Genome annotation databases

EnsembliENST00000401710; ENSP00000385580; ENSG00000179915.
GeneIDi9378.
UCSCiuc061jbd.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007462 Genomic DNA. No translation available.
AC007560 Genomic DNA. No translation available.
AC007680 Genomic DNA. No translation available.
AC007682 Genomic DNA. No translation available.
AC009234 Genomic DNA. No translation available.
AC010721 Genomic DNA. No translation available.
AC068715 Genomic DNA. No translation available.
AC068725 Genomic DNA. No translation available.
AC069550 Genomic DNA. No translation available.
AC078994 Genomic DNA. No translation available.
RefSeqiNP_001317021.1. NM_001330092.1.
UniGeneiHs.637685.

3D structure databases

ProteinModelPortaliE7ETA5.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiE7ETA5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000401710; ENSP00000385580; ENSG00000179915.
GeneIDi9378.
UCSCiuc061jbd.1. human.

Organism-specific databases

HGNCiHGNC:8008. NRXN1.
OpenTargetsiENSG00000179915.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118991.

Miscellaneous databases

ChiTaRSiNRXN1. human.

Gene expression databases

BgeeiENSG00000179915.
ExpressionAtlasiE7ETA5. baseline and differential.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR001791. Laminin_G.
IPR029824. Neurexin-1.
IPR003585. Neurexin-like.
IPR027789. Syndecan/Neurexin_dom.
[Graphical view]
PANTHERiPTHR10127:SF565. PTHR10127:SF565. 2 hits.
PfamiPF02210. Laminin_G_2. 1 hit.
PF01034. Syndecan. 1 hit.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
SM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 2 hits.
PROSITEiPS50025. LAM_G_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE7ETA5_HUMAN
AccessioniPrimary (citable) accession number: E7ETA5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: May 27, 2015
Last modified: November 30, 2016
This is version 49 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.