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Protein
Submitted name:

Zinc finger protein ZFPM2

Gene

ZFPM2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationPROSITE-ProRule annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger protein ZFPM2Imported
Gene namesi
Name:ZFPM2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000169946.13.
HGNCiHGNC:16700. ZFPM2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000169946.

PTM / Processingi

Proteomic databases

MaxQBiE7ET52.

Expressioni

Gene expression databases

BgeeiENSG00000169946.
ExpressionAtlasiE7ET52. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini112 – 145CCHC FOG-typeInterPro annotationAdd BLAST34
Domaini164 – 193C2H2-typeInterPro annotationAdd BLAST30
Domaini231 – 258C2H2-typeInterPro annotationAdd BLAST28
Domaini410 – 443CCHC FOG-typeInterPro annotationAdd BLAST34
Domaini549 – 582CCHC FOG-typeInterPro annotationAdd BLAST34
Domaini716 – 749CCHC FOG-typeInterPro annotationAdd BLAST34
Domaini981 – 1014CCHC FOG-typeInterPro annotationAdd BLAST34

Sequence similaritiesi

Belongs to the FOG (Friend of GATA) family.PROSITE-ProRule annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00530000063823.

Family and domain databases

InterProiView protein in InterPro
IPR034731. ZF_CCHC_FOG.
IPR036236. Znf_C2H2_sf.
IPR013087. Znf_C2H2_type.
SMARTiView protein in SMART
SM00355. ZnF_C2H2. 8 hits.
SUPFAMiSSF57667. SSF57667. 6 hits.
PROSITEiView protein in PROSITE
PS51810. ZF_CCHC_FOG. 5 hits.
PS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.

Sequencei

Sequence statusi: Complete.

E7ET52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLNNNSLKT KAQVPMVLTA GPKWLLDVTW QGVEDNKNNC IVYSKGGQLW
60 70 80 90 100
CTTTKAISEG EELIAFVVDF DSRLQAASQM TLTEGMYPAR LLDSIQLLPQ
110 120 130 140 150
QAAMASILPT AIVNKDIFPC KSCGIWYRSE RNLQAHLMYY CSGRQREAAP
160 170 180 190 200
VSEENEDSAH QISSLCPFPQ CTKSFSNARA LEMHLNSHSG VKMEEFLPPG
210 220 230 240 250
ASLKCTVCSY TADSVINFHQ HLFSHLTQAA FRCNHCHFGF QTQRELLQHQ
260 270 280 290 300
ELHVPSGKLP RESDMEHSPS ATEDSLQPAT DLLTRSELPQ SQKAMQTKDA
310 320 330 340 350
SSDTELDKCE KKTQLFLTNQ RPEIQPTTNK QSFSYTKIKS EPSSPRLASS
360 370 380 390 400
PVQPNIGPSF PVGPFLSQFS FPQDITMVPQ ASEILAKMSE LVHRRLRHGS
410 420 430 440 450
SSYPPVIYSP LMPKGATCFE CNITFNNLDN YLVHKKHYCS SRWQQMAKSP
460 470 480 490 500
EFPSVSEKMP EALSPNTGQT SINLLNPAAH SADPENPLLQ TSCINSSTVL
510 520 530 540 550
DLIGPNGKGH DKDFSTQTKK LSTSSNNDDK INGKPVDVKN PSVPLVDGES
560 570 580 590 600
DPNKTTCEAC NITFSRHETY MVHKQYYCAT RHDPPLKRSA SNKVPAMQRT
610 620 630 640 650
MRTRKRRKMY EMCLPEQEQR PPLVQQRFLD VANLNNPCTS TQEPTEGLGE
660 670 680 690 700
CYHPRCDIFP GIVSKHLETS LTINKCVPVS KCDTTHSSVS CLEMDVPIDL
710 720 730 740 750
SKKCLSQSER TTTSPKRLLD YHECTVCKIS FNKVENYLAH KQNFCPVTAH
760 770 780 790 800
QRNDLGQLDG KVFPNPESER NSPDVSYERS IIKCEKNGNL KQPSPNGNLF
810 820 830 840 850
SSHLATLQGL KVFSEAAQLI ATKEENRHLF LPQCLYPGAI KKAKGADQLS
860 870 880 890 900
PYYGIKPSDY ISGSLVIHNT DIEQSRNAEN ESPKGQASSN GCAALKKDSL
910 920 930 940 950
PLLPKNRGMV IVNGGLKQDE RPAANPQQEN ISQNPQHEDD HKSPSWISEN
960 970 980 990 1000
PLAANENVSP GIPSAEEQLS SIAKGVNGSS QAPTSGKYCR LCDIQFNNLS
1010
NFITHKKFYC SSHAAEHVK
Length:1,019
Mass (Da):113,305
Last modified:March 8, 2011 - v1
Checksum:iC59658EE6CEB775E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012564 Genomic DNA. No translation available.
AC021498 Genomic DNA. No translation available.
AC021546 Genomic DNA. No translation available.
AC041039 Genomic DNA. No translation available.
AC090142 Genomic DNA. No translation available.
AC090827 Genomic DNA. No translation available.
KF458816 Genomic DNA. No translation available.
KF458817 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000517361; ENSP00000428720; ENSG00000169946.
ENST00000520492; ENSP00000430757; ENSG00000169946.
UCSCiuc064pkr.1. human.

Similar proteinsi

Entry informationi

Entry nameiE7ET52_HUMAN
AccessioniPrimary (citable) accession number: E7ET52
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: November 22, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported