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Protein
Submitted name:

Intercellular adhesion molecule 1

Gene

ICAM1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Intercellular adhesion molecule 1Imported
Gene namesi
Name:ICAM1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000090339.8
HGNCiHGNC:5344 ICAM1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei259 – 281HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000090339

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500321732927 – 310Sequence analysisAdd BLAST284

Proteomic databases

MaxQBiE7ESS4
PeptideAtlasiE7ESS4
PRIDEiE7ESS4

Expressioni

Gene expression databases

BgeeiENSG00000090339
ExpressionAtlasiE7ESS4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE7ESS4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IPHM Eukaryota
ENOG410YQ1Q LUCA
GeneTreeiENSGT00530000063246

Family and domain databases

Gene3Di2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
SUPFAMiSSF48726 SSF48726, 3 hits

Sequencei

Sequence statusi: Complete.

E7ESS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPSSPRPAL PALLVLLGAL FPVSEAQVHL ALGDQRLNPT VTYGNDSFSA
60 70 80 90 100
KASVSVTAED EGTQRLTCAV ILGNQSQETL QTVTIYSFPA PNVILTKPEV
110 120 130 140 150
SEGTEVTVKC EAHPRAKVTL NGVPAQPLGP RAQLLLKATP EDNGRSFSCS
160 170 180 190 200
ATLEVAGQLI HKNQTRELRV LYGPRLDERD CPGNWTWPEN SQQTPMCQAW
210 220 230 240 250
GNPLPELKCL KDGTFPLPIG ESVTVTRDLE GTYLCRARST QGEVTRKVTV
260 270 280 290 300
NVLSPRYEIV IITVVAAAVI MGTAGLSTYL YNRQRKIKKY RLQQAQKGTP
310
MKPNTQATPP
Length:310
Mass (Da):33,700
Last modified:March 8, 2011 - v1
Checksum:i5BCC3095AE66CD75
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011511 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000423829; ENSP00000413124; ENSG00000090339
UCSCiuc010xle.2 human

Similar proteinsi

Entry informationi

Entry nameiE7ESS4_HUMAN
AccessioniPrimary (citable) accession number: E7ESS4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: April 25, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health