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E7ESI6 (E7ESI6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:TXNRD1 Ensembl ENSP00000367310
OrganismHomo sapiens (Human) [Reference proteome] Ensembl ENSP00000367310
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length581 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003691

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000367310

Sequences

Sequence LengthMass (Da)Tools
E7ESI6 [UniParc].

Last modified June 28, 2011. Version 2.
Checksum: DA3F2C28516C2F62

FASTA58163,981
        10         20         30         40         50         60 
MQQVMLTCKG VNRGHAVPAG PGRKPRPRRS SRLLAGEKHL TRSALLLCHT EDGRALEGTL 

        70         80         90        100        110        120 
SELAAETDLP VVFVKQRKIG GHGPTLKAYQ EGRLQKLLKM NGPEDLPKSY DYDLIIIGGG 

       130        140        150        160        170        180 
SGGLAAAKEA AQYGKKVMVL DFVTPTPLGT RWGLGGTCVN VGCIPKKLMH QAALLGQALQ 

       190        200        210        220        230        240 
DSRNYGWKVE ETVKHDWDRM IEAVQNHIGS LNWGYRVALR EKKVVYENAY GQFIGPHRIK 

       250        260        270        280        290        300 
ATNNKGKEKI YSAERFLIAT GERPRYLGIP GDKEYCISSD DLFSLPYCPG KTLVVGASYV 

       310        320        330        340        350        360 
ALECAGFLAG IGLDVTVMVR SILLRGFDQD MANKIGEHME EHGIKFIRQF VPIKVEQIEA 

       370        380        390        400        410        420 
GTPGRLRVVA QSTNSEEIIE GEYNTVMLAI GRDACTRKIG LETVGVKINE KTGKIPVTDE 

       430        440        450        460        470        480 
EQTNVPYIYA IGDILEDKVE LTPVAIQAGR LLAQRLYAGS TVKCDYENVP TTVFTPLEYG 

       490        500        510        520        530        540 
ACGLSEEKAV EKFGEENIEV YHSYFWPLEW TIPSRDNNKC YAKIICNTKD NERVVGFHVL 

       550        560        570        580 
GPNAGEVTQG FAAALKCGLT KKQLDSTIGI HPVCAEFFSF I 

« Hide

References

« Hide 'large scale' references
[1]"The finished DNA sequence of human chromosome 12."
Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team
Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R. expand/collapse author list , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A., null.
Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC089983 Genomic DNA. No translation available.
AC090107 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalE7ESI6.
SMRE7ESI6. Positions 25-579.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEE7ESI6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000378070; ENSP00000367310; ENSG00000198431.

Organism-specific databases

HGNCHGNC:12437. TXNRD1.
GenAtlasSearch...

Gene expression databases

ArrayExpressE7ESI6.
BgeeE7ESI6.

Family and domain databases

Gene3D3.30.390.30. 1 hit.
3.40.30.10. 1 hit.
InterProIPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR012999. Pyr_OxRdtase_I_AS.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR012336. Thioredoxin-like_fold.
IPR006338. Thioredoxin/glutathione_Rdtase.
[Graphical view]
PANTHERPTHR22912:SF23. PTHR22912:SF23. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
SUPFAMSSF55424. SSF55424. 1 hit.
TIGRFAMsTIGR01438. TGR. 1 hit.
PROSITEPS00076. PYRIDINE_REDOX_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSTXNRD1. human.
NextBio35500197.

Entry information

Entry nameE7ESI6_HUMAN
AccessionPrimary (citable) accession number: E7ESI6
Entry history
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: June 28, 2011
Last modified: April 16, 2014
This is version 24 of the entry and version 2 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.