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E7ES19

- E7ES19_HUMAN

UniProt

E7ES19 - E7ES19_HUMAN

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Protein
Submitted name: Thrombospondin-4
Gene
THBS4
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. cell adhesion Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Thrombospondin-4Imported
Gene namesi
Name:THBS4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 5

Organism-specific databases

HGNCiHGNC:11788. THBS4.

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Expressioni

Gene expression databases

ArrayExpressiE7ES19.
BgeeiE7ES19.

Structurei

3D structure databases

ProteinModelPortaliE7ES19.
SMRiE7ES19. Positions 127-171, 199-861.

Family & Domainsi

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotations, RepeatSAAS annotations

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
4.10.1080.10. 2 hits.
InterProiIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR018097. EGF_Ca-bd_CS.
IPR001791. Laminin_G.
IPR024665. Thbs/COMP_coiled-coil.
IPR003367. Thrombospondin_3-like_rpt.
IPR017897. Thrombospondin_3_rpt.
IPR008859. Thrombospondin_C.
IPR028974. TSP_type-3_rpt.
[Graphical view]
PfamiPF11598. COMP. 1 hit.
PF07645. EGF_CA. 2 hits.
PF02412. TSP_3. 6 hits.
PF05735. TSP_C. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 2 hits.
SM00179. EGF_CA. 2 hits.
SM00210. TSPN. 1 hit.
[Graphical view]
SUPFAMiSSF103647. SSF103647. 2 hits.
SSF49899. SSF49899. 2 hits.
PROSITEiPS01186. EGF_2. 1 hit.
PS50026. EGF_3. 4 hits.
PS01187. EGF_CA. 2 hits.
PS51234. TSP3. 8 hits.
PS51236. TSP_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E7ES19-1 [UniParc]FASTAAdd to Basket

« Hide

MGRLNKAILR YLKNDGKVHL VVFNNLQLAD GRRHRILLRL SNLQRGAGSL    50
ELYLDCIQVD SVHNLPRAFA GPSQKPETIE LRTFQRKPQD FLEELKLVVR 100
GSLFQVASLQ DCFLQQSEPL AATGTGDFNR QFLGQMTQLN QLLGEVKDLL 150
RQQVKETSFL RNTIAECQAC GPLKFQSPTP STVVPPAPPA PPTRPPRRCD 200
SNPCFRGVQC TDSRDGFQCG PCPEGYTGNG ITCIDVDECK YHPCYPGVHC 250
INLSPGFRCD ACPVGFTGPM VQGVGISFAK SNKQVCTDID ECRNGACVPN 300
SICVNTLGSY RCGPCKPGYT GDQIRGCKAE RNCRNPELNP CSVNAQCIEE 350
RQGDVTCVCG VGWAGDGYIC GKDVDIDSYP DEELPCSARN CKKDNCKYVP 400
NSGQEDADRD GIGDACDEDA DGDGILNEQD NCVLIHNVDQ RNSDKDIFGD 450
ACDNCLSVLN NDQKDTDGDG RGDACDDDMD GDGIKNILDN CPKFPNRDQR 500
DKDGDGVGDA CDSCPDVSNP NQSDVDNDLV GDSCDTNQDS DGDGHQDSTD 550
NCPTVINSAQ LDTDKDGIGD ECDDDDDNDG IPDLVPPGPD NCRLVPNPAQ 600
EDSNSDGVGD ICESDFDQDQ VIDRIDVCPE NAEVTLTDFR AYQTVVLDPE 650
GDAQIDPNWV VLNQGMEIVQ TMNSDPGLAV GYTAFNGVDF EGTFHVNTQT 700
DDDYAGFIFG YQDSSSFYVV MWKQTEQTYW QATPFRAVAE PGIQLKAVKS 750
KTGPGEHLRN SLWHTGDTSD QVRLLWKDSR NVGWKDKVSY RWFLQHRPQV 800
GYIRVRFYEG SELVADSGVT IDTTMRGGRL GVFCFSQENI IWSNLKYRCN 850
DTIPEDFQEF QTQNFDRFDN 870
Length:870
Mass (Da):96,006
Last modified:March 8, 2011 - v1
Checksum:i03F25B1B5FC43A24
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC012636 Genomic DNA. No translation available.
AC112184 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000511733; ENSP00000422298; ENSG00000113296.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC012636 Genomic DNA. No translation available.
AC112184 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali E7ES19.
SMRi E7ES19. Positions 127-171, 199-861.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000511733 ; ENSP00000422298 ; ENSG00000113296 .

Organism-specific databases

HGNCi HGNC:11788. THBS4.
GenAtlasi Search...

Miscellaneous databases

GenomeRNAii 7060.
NextBioi 35500124.

Gene expression databases

ArrayExpressi E7ES19.
Bgeei E7ES19.

Family and domain databases

Gene3Di 2.60.120.200. 1 hit.
4.10.1080.10. 2 hits.
InterProi IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR018097. EGF_Ca-bd_CS.
IPR001791. Laminin_G.
IPR024665. Thbs/COMP_coiled-coil.
IPR003367. Thrombospondin_3-like_rpt.
IPR017897. Thrombospondin_3_rpt.
IPR008859. Thrombospondin_C.
IPR028974. TSP_type-3_rpt.
[Graphical view ]
Pfami PF11598. COMP. 1 hit.
PF07645. EGF_CA. 2 hits.
PF02412. TSP_3. 6 hits.
PF05735. TSP_C. 1 hit.
[Graphical view ]
SMARTi SM00181. EGF. 2 hits.
SM00179. EGF_CA. 2 hits.
SM00210. TSPN. 1 hit.
[Graphical view ]
SUPFAMi SSF103647. SSF103647. 2 hits.
SSF49899. SSF49899. 2 hits.
PROSITEi PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 4 hits.
PS01187. EGF_CA. 2 hits.
PS51234. TSP3. 8 hits.
PS51236. TSP_CTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 5."
    Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
    , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
    Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE7ES19_HUMAN
AccessioniPrimary (citable) accession number: E7ES19
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: September 3, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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