ID   E7ERM9_HUMAN            Unreviewed;       128 AA.
AC   E7ERM9;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=TRAF family member associated NFKB activator {ECO:0000313|Ensembl:ENSP00000388930.1};
GN   Name=TANK {ECO:0000313|Ensembl:ENSP00000388930.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000388930.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000388930.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA   Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA   Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA   Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA   Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA   Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA   Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA   Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA   Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA   Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA   Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA   Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA   Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA   Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA   Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA   Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT   4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0007829|PubMed:22814378}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA   Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA   Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA   Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT   "N-terminal acetylome analyses and functional insights of the N-terminal
RT   acetyltransferase NatB.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
RN   [3] {ECO:0000313|Ensembl:ENSP00000388930.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC009299; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC009313; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; E7ERM9; -.
DR   SMR; E7ERM9; -.
DR   MassIVE; E7ERM9; -.
DR   MaxQB; E7ERM9; -.
DR   PeptideAtlas; E7ERM9; -.
DR   ProteomicsDB; 17817; -.
DR   Ensembl; ENST00000457887.5; ENSP00000388930.1; ENSG00000136560.14.
DR   UCSC; uc061oxw.1; human.
DR   HGNC; HGNC:11562; TANK.
DR   VEuPathDB; HostDB:ENSG00000136560; -.
DR   GeneTree; ENSGT00390000008712; -.
DR   ChiTaRS; TANK; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000136560; Expressed in monocyte and 205 other cell types or tissues.
DR   ExpressionAtlas; E7ERM9; baseline and differential.
DR   GO; GO:0007249; P:canonical NF-kappaB signal transduction; IEA:InterPro.
DR   InterPro; IPR039669; TANK.
DR   PANTHER; PTHR15249; TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR; 1.
DR   PANTHER; PTHR15249:SF0; TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR; 1.
PE   1: Evidence at protein level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Proteomics identification {ECO:0007829|EPD:E7ERM9,
KW   ECO:0007829|MaxQB:E7ERM9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   COILED          27..61
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   128 AA;  14900 MW;  8E29884379637AF7 CRC64;
     MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS
     QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKL YPVLDFTITS
     FVSVYVDW
//