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E7ERM3

- E7ERM3_HUMAN

UniProt

E7ERM3 - E7ERM3_HUMAN

Protein
Submitted name:

Angiomotin

Gene

AMOT

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (08 Mar 2011)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. actin cytoskeleton organization Source: Ensembl
    2. blood vessel endothelial cell migration Source: Ensembl
    3. cell migration involved in gastrulation Source: Ensembl
    4. cellular protein localization Source: Ensembl
    5. chemotaxis Source: Ensembl
    6. establishment of cell polarity involved in ameboidal cell migration Source: Ensembl
    7. gastrulation with mouth forming second Source: Ensembl
    8. in utero embryonic development Source: Ensembl
    9. negative regulation of GTPase activity Source: Ensembl
    10. positive regulation of embryonic development Source: Ensembl
    11. regulation of small GTPase mediated signal transduction Source: Ensembl
    12. vasculogenesis Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    AngiomotinImported
    Gene namesi
    Name:AMOTImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome X

    Organism-specific databases

    HGNCiHGNC:17810. AMOT.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasmic vesicle Source: Ensembl
    2. lamellipodium Source: Ensembl
    3. tight junction Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiE7ERM3.
    BgeeiE7ERM3.

    Structurei

    3D structure databases

    ProteinModelPortaliE7ERM3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    InterProiIPR009114. Angiomotin.
    IPR024646. Angiomotin_C.
    [Graphical view]
    PANTHERiPTHR14826. PTHR14826. 1 hit.
    PfamiPF12240. Angiomotin_C. 1 hit.
    [Graphical view]
    PRINTSiPR01807. ANGIOMOTIN.

    Sequencei

    Sequence statusi: Complete.

    E7ERM3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEHRGPPPEY PFKGMPPQSV VCKPQEPGHF YSEHRLNQPG RTEGQLMRYQ    50
    HPPEYGAARP AQDISLPLSA RNSQPHSPTS SLTSGGSLPL LQSPPSTRLS 100
    PARHPLVPNQ GDHSAHLPRP QQHFLPNQAH QGDHYRLSQP GLSQQQQQQQ 150
    QQHHHHHHHQ QQQQQQPQQQ PGEAYSAMPR AQPSSASYQP VPADPFAIVS 200
    RAQQMVEILS DENRNLRQEL EGCYEKVARL QKVETEIQRV SEAYENLVKS 250
    SSKREALEKA MRNKLEGEIR RMHDFNRDLR ERLETANKQL AEKEYEGSED 300
    TRKTISQLFA KNKESQREKE KLEAELATAR STNEDQRRHI EIRDQALSNA 350
    QAKVVKLEEE LKKKQVYVDK VEKMQQALVQ LQAACEKREQ LEHRLRTRLE 400
    RELESLRIQQ RQGNCQPTNV SEYNAAALME LLREKEERIL ALEADMTKWE 450
    QKYLEENVMR HFALDAAATV AAQRDTTVIS HSPNTSYDTA LEARIQKEEE 500
    EILMANKRCL DMEGRIKTLH AQIIEKDAMI KVLQQRSRKE PSKTEQLSCM 550
    RPAKSLMSIS NAGSGLLSHS STLTGSPIME EKRDDKSWKG SLGILLGGDY 600
    RAEYVPSTPS PVPPSTPLLS AHSKTGSRDC STQTERGTES NKTAAVAPIS 650
    VPAPVAAAAT AAAITATAAT ITTTMVAAAP VAVAAAAAPA AAAAPSPATA 700
    AATAAAVSPA AAGQIPAAAS VASAAAVAPS AAAAAAVQVA PAAPAPVPAP 750
    ALVPVPAPAA AQASAPAQTQ APTSAPAVAP TPAPTPTPAV AQAEVPASPA 800
    TGPGPHRLSI PSLTCNPDKT DGPVFHSNTL ERKTPIQILG QEPDAEMVEY 850
    LI 852
    Length:852
    Mass (Da):92,504
    Last modified:March 8, 2011 - v1
    Checksum:iF33D9187A8AFE5B2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004827 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000371962; ENSP00000361030; ENSG00000126016.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004827 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E7ERM3.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000371962 ; ENSP00000361030 ; ENSG00000126016 .

    Organism-specific databases

    HGNCi HGNC:17810. AMOT.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi AMOT. human.
    NextBioi 35500066.

    Gene expression databases

    ArrayExpressi E7ERM3.
    Bgeei E7ERM3.

    Family and domain databases

    InterProi IPR009114. Angiomotin.
    IPR024646. Angiomotin_C.
    [Graphical view ]
    PANTHERi PTHR14826. PTHR14826. 1 hit.
    Pfami PF12240. Angiomotin_C. 1 hit.
    [Graphical view ]
    PRINTSi PR01807. ANGIOMOTIN.
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of the human X chromosome."
      Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
      , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
      Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE7ERM3_HUMAN
    AccessioniPrimary (citable) accession number: E7ERM3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3