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Protein
Submitted name:

Voltage-dependent calcium channel subunit alpha-2/delta-1

Gene

CACNA2D1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-dependent calcium channel subunit alpha-2/delta-1Imported
Gene namesi
Name:CACNA2D1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:1399. CACNA2D1.

Expressioni

Gene expression databases

BgeeiE7ERK3.
ExpressionAtlasiE7ERK3. baseline and differential.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliE7ERK3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000062904.
KOiK04858.

Family and domain databases

InterProiIPR013608. VWA_N.
IPR002035. VWF_A.
[Graphical view]
PfamiPF08399. VWA_N. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.

Sequencei

Sequence statusi: Complete.

E7ERK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAGCLLALT LTLFQSLLIG PSSEEPFPSA VTIKSWVDKM QEDLVTLAKT
60 70 80 90 100
ASGVNQLVDI YEKYQDLYTV EPNNARQLVE IAARDIEKLL SNRSKALVRL
110 120 130 140 150
ALEAEKVQAA HQWREDFASN EVVYYNAKDD LDPEKNDSEP GSQRIKPVFI
160 170 180 190 200
EDANFGRQIS YQHAAVHIPT DIYEGSTIVL NELNWTSALD EVFKKNREED
210 220 230 240 250
PSLLWQVFGS ATGLARYYPA SPWVDNSRTP NKIDLYDVRR RPWYIQGAAS
260 270 280 290 300
PKDMLILVDV SGSVSGLTLK LIRTSVSEML ETLSDDDFVN VASDSKEISP

SPEEIFNAE
Length:309
Mass (Da):34,621
Last modified:March 8, 2011 - v1
Checksum:i7A3D8ADCAA481D7C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004892 Genomic DNA. No translation available.
AC004970 Genomic DNA. No translation available.
AC004989 Genomic DNA. No translation available.
AC005159 Genomic DNA. No translation available.
AC006145 Genomic DNA. No translation available.
AC008283 Genomic DNA. No translation available.
KF458487 Genomic DNA. No translation available.
RefSeqiNP_001289819.1. NM_001302890.1.
UniGeneiHs.282151.
Hs.592625.
Hs.743228.

Genome annotation databases

EnsembliENST00000423588; ENSP00000405395; ENSG00000153956.
GeneIDi781.
KEGGihsa:781.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004892 Genomic DNA. No translation available.
AC004970 Genomic DNA. No translation available.
AC004989 Genomic DNA. No translation available.
AC005159 Genomic DNA. No translation available.
AC006145 Genomic DNA. No translation available.
AC008283 Genomic DNA. No translation available.
KF458487 Genomic DNA. No translation available.
RefSeqiNP_001289819.1. NM_001302890.1.
UniGeneiHs.282151.
Hs.592625.
Hs.743228.

3D structure databases

ProteinModelPortaliE7ERK3.
ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiE7ERK3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000423588; ENSP00000405395; ENSG00000153956.
GeneIDi781.
KEGGihsa:781.

Organism-specific databases

CTDi781.
HGNCiHGNC:1399. CACNA2D1.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00530000062904.
KOiK04858.

Miscellaneous databases

ChiTaRSiCACNA2D1. human.
NextBioi35500054.

Gene expression databases

BgeeiE7ERK3.
ExpressionAtlasiE7ERK3. baseline and differential.

Family and domain databases

InterProiIPR013608. VWA_N.
IPR002035. VWF_A.
[Graphical view]
PfamiPF08399. VWA_N. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE7ERK3_HUMAN
AccessioniPrimary (citable) accession number: E7ERK3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: May 27, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.