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E7ERH2

- E7ERH2_HUMAN

UniProt

E7ERH2 - E7ERH2_HUMAN

Protein
Submitted name:

S-phase kinase-associated protein 1

Gene

SKP1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Biological processi

    1. ubiquitin-dependent protein catabolic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    S-phase kinase-associated protein 1Imported
    Gene namesi
    Name:SKP1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 5

    Organism-specific databases

    HGNCiHGNC:10899. SKP1.

    Expressioni

    Gene expression databases

    ArrayExpressiE7ERH2.
    BgeeiE7ERH2.

    Structurei

    3D structure databases

    ProteinModelPortaliE7ERH2.
    SMRiE7ERH2. Positions 3-142.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.30.710.10. 1 hit.
    InterProiIPR011333. BTB/POZ_fold.
    IPR016897. E3_ubiquit_lig_SCF_Skp.
    IPR001232. Skp1_comp.
    IPR016072. Skp1_comp_dimer.
    IPR016073. Skp1_comp_POZ.
    [Graphical view]
    PANTHERiPTHR11165. PTHR11165. 1 hit.
    PfamiPF01466. Skp1. 1 hit.
    PF03931. Skp1_POZ. 1 hit.
    [Graphical view]
    PIRSFiPIRSF028729. E3_ubiquit_lig_SCF_Skp. 1 hit.
    SMARTiSM00512. Skp1. 1 hit.
    [Graphical view]
    SUPFAMiSSF54695. SSF54695. 1 hit.
    SSF81382. SSF81382. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    E7ERH2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPSIKLQSSD GEIFEVDVEI AKQSVTIKTM LEDLGMDDEG DDDPVPLPNV    50
    NAAILKKVIQ WCTHHKDDPP PPEDDENKEK RTDDIPVWDQ EFLKVDQGTL 100
    FELILAANYL DIKGLLDVTC KTVANMIKGK TPEEIRKTFN IK 142
    Length:142
    Mass (Da):16,034
    Last modified:March 8, 2011 - v1
    Checksum:i229D2563CA67C179
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei142 – 1421Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC011336 Genomic DNA. No translation available.
    AC104109 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000519321; ENSP00000429415; ENSG00000113558.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC011336 Genomic DNA. No translation available.
    AC104109 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E7ERH2.
    SMRi E7ERH2. Positions 3-142.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000519321 ; ENSP00000429415 ; ENSG00000113558 .

    Organism-specific databases

    HGNCi HGNC:10899. SKP1.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi SKP1. human.
    NextBioi 35500034.

    Gene expression databases

    ArrayExpressi E7ERH2.
    Bgeei E7ERH2.

    Family and domain databases

    Gene3Di 3.30.710.10. 1 hit.
    InterProi IPR011333. BTB/POZ_fold.
    IPR016897. E3_ubiquit_lig_SCF_Skp.
    IPR001232. Skp1_comp.
    IPR016072. Skp1_comp_dimer.
    IPR016073. Skp1_comp_POZ.
    [Graphical view ]
    PANTHERi PTHR11165. PTHR11165. 1 hit.
    Pfami PF01466. Skp1. 1 hit.
    PF03931. Skp1_POZ. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF028729. E3_ubiquit_lig_SCF_Skp. 1 hit.
    SMARTi SM00512. Skp1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54695. SSF54695. 1 hit.
    SSF81382. SSF81382. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and comparative analysis of human chromosome 5."
      Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
      , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
      Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    5. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE7ERH2_HUMAN
    AccessioniPrimary (citable) accession number: E7ERH2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3