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Protein
Submitted name:

S-phase kinase-associated protein 1

Gene

SKP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
S-phase kinase-associated protein 1Imported
Gene namesi
Name:SKP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

HGNCiHGNC:10899. SKP1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000113558.

PTM / Processingi

Proteomic databases

MaxQBiE7ERH2.
PaxDbiE7ERH2.
PeptideAtlasiE7ERH2.
PRIDEiE7ERH2.

Expressioni

Gene expression databases

BgeeiENSG00000113558.
ExpressionAtlasiE7ERH2. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000231487.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 67Skp1_POZInterPro annotationAdd BLAST66
Domaini113 – 142Skp1InterPro annotationAdd BLAST30

Sequence similaritiesi

Belongs to the SKP1 family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1724. Eukaryota.
COG5201. LUCA.
GeneTreeiENSGT00390000012652.

Family and domain databases

InterProiIPR016897. SKP1.
IPR001232. SKP1-like.
IPR011333. SKP1/BTB/POZ.
IPR016072. Skp1_comp_dimer.
IPR016073. Skp1_comp_POZ.
[Graphical view]
PfamiPF01466. Skp1. 1 hit.
PF03931. Skp1_POZ. 1 hit.
[Graphical view]
PIRSFiPIRSF028729. E3_ubiquit_lig_SCF_Skp. 1 hit.
SMARTiSM00512. Skp1. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
SSF81382. SSF81382. 1 hit.

Sequencei

Sequence statusi: Fragment.

E7ERH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSIKLQSSD GEIFEVDVEI AKQSVTIKTM LEDLGMDDEG DDDPVPLPNV
60 70 80 90 100
NAAILKKVIQ WCTHHKDDPP PPEDDENKEK RTDDIPVWDQ EFLKVDQGTL
110 120 130 140
FELILAANYL DIKGLLDVTC KTVANMIKGK TPEEIRKTFN IK
Length:142
Mass (Da):16,034
Last modified:March 8, 2011 - v1
Checksum:i229D2563CA67C179
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei142Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011336 Genomic DNA. No translation available.
AC104109 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000519321; ENSP00000429415; ENSG00000113558.
UCSCiuc063hai.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011336 Genomic DNA. No translation available.
AC104109 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000231487.

Proteomic databases

MaxQBiE7ERH2.
PaxDbiE7ERH2.
PeptideAtlasiE7ERH2.
PRIDEiE7ERH2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000519321; ENSP00000429415; ENSG00000113558.
UCSCiuc063hai.1. human.

Organism-specific databases

HGNCiHGNC:10899. SKP1.
OpenTargetsiENSG00000113558.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1724. Eukaryota.
COG5201. LUCA.
GeneTreeiENSGT00390000012652.

Miscellaneous databases

ChiTaRSiSKP1. human.

Gene expression databases

BgeeiENSG00000113558.
ExpressionAtlasiE7ERH2. baseline and differential.

Family and domain databases

InterProiIPR016897. SKP1.
IPR001232. SKP1-like.
IPR011333. SKP1/BTB/POZ.
IPR016072. Skp1_comp_dimer.
IPR016073. Skp1_comp_POZ.
[Graphical view]
PfamiPF01466. Skp1. 1 hit.
PF03931. Skp1_POZ. 1 hit.
[Graphical view]
PIRSFiPIRSF028729. E3_ubiquit_lig_SCF_Skp. 1 hit.
SMARTiSM00512. Skp1. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
SSF81382. SSF81382. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE7ERH2_HUMAN
AccessioniPrimary (citable) accession number: E7ERH2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: November 30, 2016
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.