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Protein
Submitted name:

T-cell differentiation antigen CD6

Gene

CD6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
T-cell differentiation antigen CD6Imported
Gene namesi
Name:CD6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:1691. CD6.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei298 – 32326HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence analysisAdd
BLAST
Chaini18 – 422405Sequence analysisPRO_5003217321Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiE7ER04.
PeptideAtlasiE7ER04.

Expressioni

Gene expression databases

BgeeiE7ER04.
ExpressionAtlasiE7ER04. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000323280.

Structurei

3D structure databases

ProteinModelPortaliE7ER04.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini45 – 156112SRCRInterPro annotationAdd
BLAST
Domaini161 – 260100SRCRInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IK9E. Eukaryota.
ENOG410YC2B. LUCA.
GeneTreeiENSGT00840000129699.

Family and domain databases

Gene3Di3.10.250.10. 2 hits.
InterProiIPR001190. SRCR.
IPR017448. SRCR-like_dom.
[Graphical view]
PfamiPF00530. SRCR. 2 hits.
[Graphical view]
PRINTSiPR00258. SPERACTRCPTR.
SMARTiSM00202. SR. 2 hits.
[Graphical view]
SUPFAMiSSF56487. SSF56487. 2 hits.
PROSITEiPS00420. SRCR_1. 1 hit.
PS50287. SRCR_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E7ER04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWLFFGITGL LTAALSGHPS PAPPDQLNTS SAESELWEPG ERLPVRLTNG
60 70 80 90 100
SSSCSGTVEV RLEASWEPAC GALWDSRAAE AVCRALGCGG AEAASQLAPP
110 120 130 140 150
TPELPPPPAA GNTSVAANAT LAGAPALLCS GAEWRLCEVV EHACRSDGRR
160 170 180 190 200
ARVTCAENRA LRLVDGGGAC AGRVEMLEHG EWGSVCDDTW DLEDAHVVCR
210 220 230 240 250
QLGCGWAVQA LPGLHFTPGR GPIHRDQVNC SGAEAYLWDC PGLPGQHYCG
260 270 280 290 300
HKEDAGAVCS ASRSLHNLST PEVPASVQTV TIESSVTVKI ENKESRELML
310 320 330 340 350
LIPSIVLGIL LLGSLIFIAF ILLRIKGKYV FMLPIQVQAP PPEDSDSGSD
360 370 380 390 400
SDYEHYDFSA QPPVALTTFY NSQRHRVTDE EVQQSRFQMP PLEEGLEELH
410 420
ASHIPTANPG HCITDPPSLG PQ
Length:422
Mass (Da):45,002
Last modified:June 28, 2011 - v2
Checksum:i4922D909FB5D007C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei422 – 4221Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003721 Genomic DNA. No translation available.
KF455397 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000433107; ENSP00000410638; ENSG00000013725.
UCSCiuc058bxe.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003721 Genomic DNA. No translation available.
KF455397 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE7ER04.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000323280.

Proteomic databases

PaxDbiE7ER04.
PeptideAtlasiE7ER04.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000433107; ENSP00000410638; ENSG00000013725.
UCSCiuc058bxe.1. human.

Organism-specific databases

HGNCiHGNC:1691. CD6.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IK9E. Eukaryota.
ENOG410YC2B. LUCA.
GeneTreeiENSGT00840000129699.

Gene expression databases

BgeeiE7ER04.
ExpressionAtlasiE7ER04. baseline and differential.

Family and domain databases

Gene3Di3.10.250.10. 2 hits.
InterProiIPR001190. SRCR.
IPR017448. SRCR-like_dom.
[Graphical view]
PfamiPF00530. SRCR. 2 hits.
[Graphical view]
PRINTSiPR00258. SPERACTRCPTR.
SMARTiSM00202. SR. 2 hits.
[Graphical view]
SUPFAMiSSF56487. SSF56487. 2 hits.
PROSITEiPS00420. SRCR_1. 1 hit.
PS50287. SRCR_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE7ER04_HUMAN
AccessioniPrimary (citable) accession number: E7ER04
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: June 28, 2011
Last modified: July 6, 2016
This is version 41 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.