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Protein
Submitted name:

T-complex protein 1 subunit alpha

Gene

TCP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionChaperoneUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
T-complex protein 1 subunit alphaImported
Gene namesi
Name:TCP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000120438.11
HGNCiHGNC:11655 TCP1

Subcellular locationi

Keywords - Cellular componenti

CytoplasmSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000120438

PTM / Processingi

Proteomic databases

MaxQBiE7EQR6
PeptideAtlasiE7EQR6
PRIDEiE7EQR6

PTM databases

iPTMnetiE7EQR6

Expressioni

Gene expression databases

BgeeiENSG00000120438
ExpressionAtlasiE7EQR6 baseline and differential
GenevisibleiE7EQR6 HS

Structurei

3D structure databases

ProteinModelPortaliE7EQR6
SMRiE7EQR6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0360 Eukaryota
COG0459 LUCA
GeneTreeiENSGT00550000074878

Family and domain databases

Gene3Di1.10.560.10, 1 hit
3.30.260.10, 2 hits
3.50.7.10, 1 hit
InterProiView protein in InterPro
IPR017998 Chaperone_TCP-1
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PANTHERiPTHR11353 PTHR11353, 1 hit
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00304 TCOMPLEXTCP1
SUPFAMiSSF48592 SSF48592, 1 hit
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 2 hits

Sequencei

Sequence statusi: Complete.

E7EQR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSKIIGING DFFANMVVDA VLAIKYTDIR GQPRYPVNSV NILKAHGRSQ
60 70 80 90 100
MESMLISGYA LNCVVGSQGM PKRIVNAKIA CLDFSLQKTK MKLGVQVVIT
110 120 130 140 150
DPEKLDQIRQ RESDITKERI QKILATGANV ILTTGGIDDM CLKYFVEAGA
160 170 180 190 200
MAVRRVLKRD LKRIAKASGA TILSTLANLE GEETFEAAML GQAEEVVQER
210 220 230 240 250
ICDDELILIK NTKARTSASI ILRGANDFMC DEMERSLHDA LCVVKRVLES
260 270 280 290 300
KSVVPGGGAV EAALSIYLEN YATSMGSREQ LAIAEFARSL LVIPNTLAVN
310 320 330 340 350
AAQDSTDLVA KLRAFHNEAQ VNPERKNLKW IGLDLSNGKP RDNKQAGVFE
360 370 380 390 400
PTIVKVKSLK FATEAAITIL RIDDLIKLHP ESKDDKHGSY EDAVHSGALN

D
Length:401
Mass (Da):43,886
Last modified:March 8, 2011 - v1
Checksum:iAAE1912CB35EBF2B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL135914 Genomic DNA No translation available.
RefSeqiNP_001008897.1, NM_001008897.1
UniGeneiHs.363137

Genome annotation databases

EnsembliENST00000392168; ENSP00000376008; ENSG00000120438
GeneIDi6950
UCSCiuc003qss.4 human

Similar proteinsi

Entry informationi

Entry nameiE7EQR6_HUMAN
AccessioniPrimary (citable) accession number: E7EQR6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: April 25, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health