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E7EPV7

- E7EPV7_HUMAN

UniProt

E7EPV7 - E7EPV7_HUMAN

Protein
Submitted name:

Alpha-synuclein

Gene

SNCA

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Biological processi

    1. regulation of dopamine secretion Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Alpha-synucleinImported
    Gene namesi
    Name:SNCAImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 4

    Organism-specific databases

    HGNCiHGNC:11138. SNCA.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    Expressioni

    Gene expression databases

    ArrayExpressiE7EPV7.
    BgeeiE7EPV7.

    Structurei

    3D structure databases

    ProteinModelPortaliE7EPV7.
    SMRiE7EPV7. Positions 1-102.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    OMAiHTICIAS.

    Family and domain databases

    Gene3Di1.10.287.700. 1 hit.
    InterProiIPR001058. Synuclein.
    IPR002460. Synuclein_alpha.
    [Graphical view]
    PANTHERiPTHR13820. PTHR13820. 1 hit.
    PfamiPF01387. Synuclein. 1 hit.
    [Graphical view]
    PRINTSiPR01212. ASYNUCLEIN.
    PR01211. SYNUCLEIN.

    Sequencei

    Sequence statusi: Complete.

    E7EPV7-1 [UniParc]FASTAAdd to Basket

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    MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH    50
    GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL 100
    GKVWLCTFCV TFISW 115
    Length:115
    Mass (Da):11,777
    Last modified:March 8, 2011 - v1
    Checksum:i2F503117A709E2C5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC093759 Genomic DNA. No translation available.
    AC097478 Genomic DNA. No translation available.
    AC108208 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000502987; ENSP00000426034; ENSG00000145335.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC093759 Genomic DNA. No translation available.
    AC097478 Genomic DNA. No translation available.
    AC108208 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E7EPV7.
    SMRi E7EPV7. Positions 1-102.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000502987 ; ENSP00000426034 ; ENSG00000145335 .

    Organism-specific databases

    HGNCi HGNC:11138. SNCA.
    GenAtlasi Search...

    Phylogenomic databases

    OMAi HTICIAS.

    Miscellaneous databases

    ChiTaRSi SNCA. human.
    NextBioi 35499806.

    Gene expression databases

    ArrayExpressi E7EPV7.
    Bgeei E7EPV7.

    Family and domain databases

    Gene3Di 1.10.287.700. 1 hit.
    InterProi IPR001058. Synuclein.
    IPR002460. Synuclein_alpha.
    [Graphical view ]
    PANTHERi PTHR13820. PTHR13820. 1 hit.
    Pfami PF01387. Synuclein. 1 hit.
    [Graphical view ]
    PRINTSi PR01212. ASYNUCLEIN.
    PR01211. SYNUCLEIN.
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE7EPV7_HUMAN
    AccessioniPrimary (citable) accession number: E7EPV7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3