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Protein

Alpha-synuclein

Gene

SNCA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-synucleinUniRule annotation
Gene namesi
Name:SNCAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000145335.15.
HGNCiHGNC:11138. SNCA.

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000145335.

PTM / Processingi

Proteomic databases

EPDiE7EPV7.
MaxQBiE7EPV7.
PeptideAtlasiE7EPV7.
PRIDEiE7EPV7.

Expressioni

Gene expression databases

BgeeiENSG00000145335.
ExpressionAtlasiE7EPV7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE7EPV7.
SMRiE7EPV7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the synuclein family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IWI2. Eukaryota.
ENOG4111TDZ. LUCA.
GeneTreeiENSGT00390000016161.

Family and domain databases

InterProiView protein in InterPro
IPR001058. Synuclein.
IPR002460. Synuclein_alpha.
PANTHERiPTHR13820. PTHR13820. 1 hit.
PTHR13820:SF5. PTHR13820:SF5. 1 hit.
PfamiView protein in Pfam
PF01387. Synuclein. 1 hit.
PRINTSiPR01212. ASYNUCLEIN.
PR01211. SYNUCLEIN.

Sequencei

Sequence statusi: Complete.

E7EPV7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH
60 70 80 90 100
GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL
110
GKVWLCTFCV TFISW
Length:115
Mass (Da):11,777
Last modified:March 8, 2011 - v1
Checksum:i2F503117A709E2C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093759 Genomic DNA. No translation available.
AC097478 Genomic DNA. No translation available.
AC108208 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000502987; ENSP00000426034; ENSG00000145335.
UCSCiuc062yfd.1. human.

Similar proteinsi

Entry informationi

Entry nameiE7EPV7_HUMAN
AccessioniPrimary (citable) accession number: E7EPV7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: March 28, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported