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Protein

Alpha-synuclein

Gene

SNCA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-synucleinUniRule annotation
Gene namesi
Name:SNCAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000145335.15.
HGNCiHGNC:11138. SNCA.

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000145335.

PTM / Processingi

Proteomic databases

EPDiE7EPV7.
MaxQBiE7EPV7.
PaxDbiE7EPV7.
PeptideAtlasiE7EPV7.
PRIDEiE7EPV7.

Expressioni

Gene expression databases

BgeeiENSG00000145335.
ExpressionAtlasiE7EPV7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE7EPV7.
SMRiE7EPV7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the synuclein family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IWI2. Eukaryota.
ENOG4111TDZ. LUCA.
GeneTreeiENSGT00390000016161.

Family and domain databases

InterProiView protein in InterPro
IPR001058. Synuclein.
IPR002460. Synuclein_alpha.
PANTHERiPTHR13820. PTHR13820. 1 hit.
PTHR13820:SF12. PTHR13820:SF12. 1 hit.
PfamiView protein in Pfam
PF01387. Synuclein. 1 hit.
PRINTSiPR01212. ASYNUCLEIN.
PR01211. SYNUCLEIN.

Sequencei

Sequence statusi: Complete.

E7EPV7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH
60 70 80 90 100
GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL
110
GKVWLCTFCV TFISW
Length:115
Mass (Da):11,777
Last modified:March 8, 2011 - v1
Checksum:i2F503117A709E2C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093759 Genomic DNA. No translation available.
AC097478 Genomic DNA. No translation available.
AC108208 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000502987; ENSP00000426034; ENSG00000145335.
UCSCiuc062yfd.1. human.

Similar proteinsi

Entry informationi

Entry nameiE7EPV7_HUMAN
AccessioniPrimary (citable) accession number: E7EPV7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: September 27, 2017
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported