Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

E7EPN9 (E7EPN9_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length2819 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000356716

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequences

Sequence LengthMass (Da)Tools
E7EPN9 [UniParc].

Last modified March 8, 2011. Version 1.
Checksum: 1BEAB582D6CCCF33

FASTA2,819308,777
        10         20         30         40         50         60 
MSEKSGQSTK AKDGKKYATL SLFNTYKGKS LETQKTTVAA RHGLQSLGKV GISRRMPPPA 

        70         80         90        100        110        120 
NLPSLKAENK GNDPNVNIVP KDGTGWASKQ EQHEEEKTPE VPPAQPKPGV AAPPEVAPAP 

       130        140        150        160        170        180 
KSWASNKQGG QGDGIQVNSQ FQQEFPSLQA AGDQEKKEKE TNDDNYGPGP SLRPPNVACW 

       190        200        210        220        230        240 
RDGGKAAGSP SSSDQDEKLP GQDESTAGTS EQNDILKVVE KRIACGPPQA KLNGQQAALA 

       250        260        270        280        290        300 
SQYRAMMPPY MFQQYPRMTY PPLHGPMRFP PSLSETNKGL RGRGPPPSWA SEPERPSILS 

       310        320        330        340        350        360 
ASELKELDKF DNLDAEADEG WAGAQMEVDY TEQLNFSDDD EQGSNSPKEN NSEDQGSKAS 

       370        380        390        400        410        420 
ENNENKKETD EVSNTKSSSQ IPAQPSVAKV PYGKGPSFNQ ERGTSSHLPP PPKLLAQQHP 

       430        440        450        460        470        480 
PPDRQAVPGR PGPFPSKQQV ADEDEIWKQR RRQQSEISAA VERARKRREE EERRMEEQRK 

       490        500        510        520        530        540 
AACAEKLKRL DEKLGILEKQ PSPEEIRERE REKEREREKE LEKEQEQERE KEREKDRERQ 

       550        560        570        580        590        600 
QEKEKELEKE QEKQREMEKE RKQEKEKELE RQKEKEKELQ KMKEQEKECE LEKEREKLEE 

       610        620        630        640        650        660 
KIEPREPNLE PMVEKQESEN SCNKEEEPVF TRQDSNRSEK EATPVVHETE PESGSQPRPA 

       670        680        690        700        710        720 
VLSGYFKQFQ KSLPPRFQRQ QEQMKQQQWQ QQQQQGVLPQ TVPSQPSSST VPPPPHRPLY 

       730        740        750        760        770        780 
QPMQPHPQHL ASMGFDPRWL MMQSYMDPRM MSGRPAMDIP PIHPGMIPPK PLMRRDQMEG 

       790        800        810        820        830        840 
SPNSSESFEH IARSARDHAI SLSEPRMLWG SDPYPHAEPQ QATTPKATEE PEDVRSEAAL 

       850        860        870        880        890        900 
DQEQITAAYS VEHNQLEAHP KADFIRESSE AQVQKFLSRS VEDVRPHHTD ANNQSACFEA 

       910        920        930        940        950        960 
PDQKTLSAPQ EERISAVESQ PSRKRSVSHG SNHTQKPDEQ RSEPSAGIPK VTSRCIDSKE 

       970        980        990       1000       1010       1020 
PIERPEEKPK KEGFIRSSEG PKPEKVYKSK SETRWGPRPS SNRREEVNDR PVRRSGPIKK 

      1030       1040       1050       1060       1070       1080 
PVLRDMKEER EQRKEKEGEK AEKVTEKVVV KPEKTEKKDL PPPPPPPQPP APIQPQSVPP 

      1090       1100       1110       1120       1130       1140 
PIQPEAEKFP STETATLAQK PSQDTEKPLE PVSTVQVEPA VKTVNQQTMA APVVKEEKQP 

      1150       1160       1170       1180       1190       1200 
EKVISKDLVI ERPRPDSRPA VKKESTLPPR TYWKEARERD WFPDQGYRGR GRGEYYSRGR 

      1210       1220       1230       1240       1250       1260 
SYRGSYGGRG RGGRGHTRDY PQYRDNKPRA EHIPSGPLRQ REESETRSES SDFEVVPKRR 

      1270       1280       1290       1300       1310       1320 
RQRGSETDTD SEIHESASDK DSLSKGKLPK REERPENKKP VKPHSSFKPD NHVRIDNRLL 

      1330       1340       1350       1360       1370       1380 
EKPYVRDDDK AKPGFLPKGE PTRRGRGGTF RRGGRDPGGR PSRPSTLRRP AYRDNQWNPR 

      1390       1400       1410       1420       1430       1440 
QSEVPKPEDG EPPRRHEQFI PIAADKRPPK FERKFDPARE RPRRQRPTRP PRQDKPPRFR 

      1450       1460       1470       1480       1490       1500 
RLREREAASK SNEVVAVPTN GTVNNVAQEP VNTLGDISGN KTPDLSNQNS SDQANEEWET 

      1510       1520       1530       1540       1550       1560 
ASESSDFNER RERDEKKNAD LNAQTVVKVG ENVLPPKREI AKRSFSSQRP VDRQNRRGNN 

      1570       1580       1590       1600       1610       1620 
GPPKSGRNFS GPRNERRSGP PSKSGKRGPF DDQPAGTTGV DLINGSSAHH QEGVPNGTGQ 

      1630       1640       1650       1660       1670       1680 
KNSKDSTGKK REDPKPGPKK PKEKVDALSQ FDLNNYASVV IIDDHPEVTV IEDPQSNLND 

      1690       1700       1710       1720       1730       1740 
DGFTEVVSKK QQKRLQDEER RKKEEQVIQV WNKKNANEKG RSQTSKLPPR FAKKQATGIQ 

      1750       1760       1770       1780       1790       1800 
QAQSSASVPP LASAPLPPST SASVPASTSA PLPATLTPVP ASTSAPVPAS TLAPVLASTS 

      1810       1820       1830       1840       1850       1860 
APVPASPLAP VSASASVSAS VPASTSAAAI TSSSAPASAP APTPILASVS TPASVTILAS 

      1870       1880       1890       1900       1910       1920 
ASIPILASAL ASTSAPTPAP AASSPAAPVI TAPTIPASAP TASVPLAPAS ASAPAPAPTP 

      1930       1940       1950       1960       1970       1980 
VSAPNPAPPA PAQTQAQTHK PVQNPLQTTS QSSKQPPPSI RLPSAQTPNG TDYVASGKSI 

      1990       2000       2010       2020       2030       2040 
QTPQSHGTLT AELWDNKVAP PAVLNDISKK LGPISPPQPP SVSAWNKPLT SFGSAPSSEG 

      2050       2060       2070       2080       2090       2100 
AKNGQESGLE IGTDTIQFGA PASNGNENEV VPVLSEKSAD KIPEPKEQRQ KQPRAGPIKA 

      2110       2120       2130       2140       2150       2160 
QKLPDLSPVE NKEHKPGPIG KERSLKNRKV KDAQQVEPEG QEKPSPATVR STDPVTTKET 

      2170       2180       2190       2200       2210       2220 
KAVSEMSTEI GTMISVSSAE YGTNAKESVT DYTTPSSSLP NTVATNNTKM EDTLVNNVPL 

      2230       2240       2250       2260       2270       2280 
PNTLPLPKRE TIQQSSSLTS VPPTTFSLTF KMESARKAWE NSPNVREKGS PVTSTAPPIA 

      2290       2300       2310       2320       2330       2340 
TGVSSSASGP STANYNSFSS ASMPQIPVAS VTPTASLSGA GTYTTSSLST KSTTTSDPPN 

      2350       2360       2370       2380       2390       2400 
ICKVKPQQLQ TSSLPSASHF SQLSCMPSLI AQQQQNPQVY VSQSAAAQIP AFYMDTSHLF 

      2410       2420       2430       2440       2450       2460 
NTQHARLAPP SLAQQQGFQP GLSQPTSVQQ IPIPIYAPLQ GQHQAQLSLG AGPAVSQAQE 

      2470       2480       2490       2500       2510       2520 
LFSSSLQPYR SQPAFMQSSL SQPSVVLSGT AIHNFPTVQH QELAKAQSGL AFQQTSNTQP 

      2530       2540       2550       2560       2570       2580 
IPILYEHQLG QASGLGGSQL IDTHLLQARA NLTQASNLYS GQVQQPGQTN FYNTAQSPSA 

      2590       2600       2610       2620       2630       2640 
LQQVTVPLPA SQLSLPNFGS TGQPLIALPQ TLQPPLQHTT PQAQAQSLSR PAQVSQPFRG 

      2650       2660       2670       2680       2690       2700 
LIPAGTQHSM IATTGKMSEM ELKAFGSGID IKPGTPPIAG RSTTPTSSPF RATSTSPNSQ 

      2710       2720       2730       2740       2750       2760 
SSKMNSIVYQ KQFQSAPATV RMTQPFPTQF APQAKQRAEV LQSTQRFFSE QQQSKQIGGG 

      2770       2780       2790       2800       2810 
KAQKVDSDSS KPPETLTDPP GVCQEKVEEK PPPAPSIATK PVRTGPIKPQ AIKTEETKS 

« Hide

References

« Hide 'large scale' references
[1]"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[2]"A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.
Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[3]"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. expand/collapse author list , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., Porter K.M., Prigmore E.
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]"Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."
Yu L.R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.
J. Proteome Res. 6:4150-4162(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[5]"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[6]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[7]"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[8]"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[9]"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[10]"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[11]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[12]"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[13]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL021579 Genomic DNA. No translation available.
AL049762 Genomic DNA. No translation available.
Z98750 Genomic DNA. No translation available.
RefSeqXP_005245081.1. XM_005245024.1.
UniGeneHs.494614.

3D structure databases

ProteinModelPortalE7EPN9.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEE7EPN9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000367742; ENSP00000356716; ENSG00000117523.
GeneID23215.
KEGGhsa:23215.

Organism-specific databases

CTD23215.
HGNCHGNC:24903. PRRC2C.
GenAtlasSearch...

Phylogenomic databases

OrthoDBEOG7DZ8J2.

Gene expression databases

ArrayExpressE7EPN9.
BgeeE7EPN9.

Family and domain databases

InterProIPR009738. BAT2_N.
[Graphical view]
PfamPF07001. BAT2_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSPRRC2C. human.
GenomeRNAi23215.
NextBio35499776.

Entry information

Entry nameE7EPN9_HUMAN
AccessionPrimary (citable) accession number: E7EPN9
Entry history
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: June 11, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.