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E7EPM6

- E7EPM6_HUMAN

UniProt

E7EPM6 - E7EPM6_HUMAN

Protein
Submitted name:

Long-chain-fatty-acid--CoA ligase 1

Gene

ACSL1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 23 (01 Oct 2014)
      Sequence version 1 (08 Mar 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. catalytic activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Long-chain-fatty-acid--CoA ligase 1Imported
    Gene namesi
    Name:ACSL1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 4

    Organism-specific databases

    HGNCiHGNC:3569. ACSL1.

    Expressioni

    Gene expression databases

    ArrayExpressiE7EPM6.
    BgeeiE7EPM6.

    Structurei

    3D structure databases

    ProteinModelPortaliE7EPM6.
    SMRiE7EPM6. Positions 147-605.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK01897.

    Family and domain databases

    InterProiIPR020845. AMP-binding_CS.
    IPR000873. AMP-dep_Synth/Lig.
    [Graphical view]
    PfamiPF00501. AMP-binding. 1 hit.
    [Graphical view]
    PROSITEiPS00455. AMP_BINDING. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E7EPM6-1 [UniParc]FASTAAdd to Basket

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    MQAHELFRYF RMPELVDFRQ YVRTLPTNTL MGFGAFAALT TFWYATRPKP    50
    LKPPCDLSMQ SVEVAGSGGA RRSALLDSDE PLVYFYDDVT TLYEGFQRGI 100
    QVSNNGPCLG SRKPDQPYEW LSYKQWVIIE QGCFAYSMVI VPLYDTLGNE 150
    AITYIVNKAE LSLVFVDKPE KAKLLLEGVE NKLIPGLKII VVMDAYGSEL 200
    VERGQRCGVE VTSMKAMEDL GRANRRKPKP PAPEDLAVIC FTSGTTGNPK 250
    GAMVTHRNIV SDCSAFVKAT ENTVNPCPDD TLISFLPLAH MFERVVECVM 300
    LCHGAKIGFF QGDIRLLMDD LKVLQPTVFP VVPRLLNRMF DRIFGQANTT 350
    LKRWLLDFAS KRKEAELRSG IIRNNSLWDR LIFHKVQSSL GGRVRLMVTG 400
    AAPVSATVLT FLRAALGCQF YEGYGQTECT AGCCLTMPGD WTAGHVGAPM 450
    PCNLIKLVDV EEMNYMAAEG EGEVCVKGPN VFQGYLKDPA KTAEALDKDG 500
    WLHTGDIGKW LPNGTLKIID RKKHIFKLAQ GEYIAPEKIE NIYMRSEPVA 550
    QVFVHGESLQ AFLIAIVVPD VETLCSWAQK RGFEGSFEEL CRNKDVKKAI 600
    LEDMVRLGKD SGLKPFEQVK GITLHPELFS IDNGLLTPTM KAKRPELRNY 650
    FRSQIDDLYS TIKV 664
    Length:664
    Mass (Da):74,282
    Last modified:March 8, 2011 - v1
    Checksum:iD10CABE7AC7A4D4A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC079257 Genomic DNA. No translation available.
    AC084871 Genomic DNA. No translation available.
    RefSeqiNP_001273640.1. NM_001286711.1.
    UniGeneiHs.406678.

    Genome annotation databases

    EnsembliENST00000507295; ENSP00000426244; ENSG00000151726.
    GeneIDi2180.
    KEGGihsa:2180.
    UCSCiuc011ckn.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC079257 Genomic DNA. No translation available.
    AC084871 Genomic DNA. No translation available.
    RefSeqi NP_001273640.1. NM_001286711.1.
    UniGenei Hs.406678.

    3D structure databases

    ProteinModelPortali E7EPM6.
    SMRi E7EPM6. Positions 147-605.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000507295 ; ENSP00000426244 ; ENSG00000151726 .
    GeneIDi 2180.
    KEGGi hsa:2180.
    UCSCi uc011ckn.1. human.

    Organism-specific databases

    CTDi 2180.
    HGNCi HGNC:3569. ACSL1.
    GenAtlasi Search...

    Phylogenomic databases

    KOi K01897.

    Miscellaneous databases

    ChiTaRSi ACSL1. human.
    GenomeRNAii 2180.
    NextBioi 35499768.

    Gene expression databases

    ArrayExpressi E7EPM6.
    Bgeei E7EPM6.

    Family and domain databases

    InterProi IPR020845. AMP-binding_CS.
    IPR000873. AMP-dep_Synth/Lig.
    [Graphical view ]
    Pfami PF00501. AMP-binding. 1 hit.
    [Graphical view ]
    PROSITEi PS00455. AMP_BINDING. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE7EPM6_HUMAN
    AccessioniPrimary (citable) accession number: E7EPM6
    Secondary accession number(s): E7EQJ5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3