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Protein
Submitted name:

Ras and Rab interactor 2

Gene

RIN2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ras and Rab interactor 2Imported
Gene namesi
Name:RIN2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:18750. RIN2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000132669.

PTM / Processingi

Proteomic databases

MaxQBiE7EPJ1.
PaxDbiE7EPJ1.
PeptideAtlasiE7EPJ1.
PRIDEiE7EPJ1.

Expressioni

Gene expression databases

BgeeiENSG00000132669.
ExpressionAtlasiE7EPJ1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000255006.

Structurei

3D structure databases

ProteinModelPortaliE7EPJ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini185 – 324VPS9InterPro annotationAdd BLAST140
Domaini354 – 445Ras-associatingInterPro annotationAdd BLAST92

Phylogenomic databases

eggNOGiKOG2320. Eukaryota.
ENOG410ZZW5. LUCA.
GeneTreeiENSGT00530000063053.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000159. RA_dom.
IPR000980. SH2.
IPR029071. Ubiquitin-rel_dom.
IPR003123. VPS9.
[Graphical view]
PfamiPF00788. RA. 1 hit.
PF02204. VPS9. 1 hit.
[Graphical view]
SMARTiSM00314. RA. 1 hit.
SM00167. VPS9. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS50200. RA. 1 hit.
PS51205. VPS9. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E7EPJ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAWTMGARG LDKRGSFFKL IDTIASEIGE LKQEMVRTDV NLENGLEPAE
60 70 80 90 100
THSMVRHKDG GYSEEEDVKT CARDSGYDSL SNRLSILDRL LHTHPIWLQL
110 120 130 140 150
SLSEEEAAEV LQAQPPGIFL VHKSTKMQKK VLSLRLPCEF GAPLKEFAIK
160 170 180 190 200
ESTYNVVLEK AMHKCILKPL KGHVEAMLKD FHMADGSWKQ LKENLQLVRQ
210 220 230 240 250
RNPQELGVFA PTPDFVDVEK IKVKFMTMQK MYSPEKKVML LLRVCKLIYT
260 270 280 290 300
VMENNSGRMY GADDFLPVLT YVIAQCDMLE LDTEIEYMME LLDPSLLHGE
310 320 330 340 350
GGYYLTSAYG ALSLIKNFQE EQAARLLSSE TRDTLRQWHK RRTTNRTIPS
360 370 380 390 400
VDDFQNYLRV AFQEVNSGCT GKTLLVRPYI TTEDVCQICA EKFKVGDPEE
410 420 430 440 450
YSLFLFVDET WQQLAEDTYP QKIKAELHSR PQPHIFHFVY KRIKNDPYGI
460
IFQNGEEDLT TS
Length:462
Mass (Da):53,116
Last modified:June 28, 2011 - v2
Checksum:i6A1E7DCC946413C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049538 Genomic DNA. No translation available.
AL132821 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000440354; ENSP00000391239; ENSG00000132669.
UCSCiuc010gcu.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049538 Genomic DNA. No translation available.
AL132821 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE7EPJ1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000255006.

Proteomic databases

MaxQBiE7EPJ1.
PaxDbiE7EPJ1.
PeptideAtlasiE7EPJ1.
PRIDEiE7EPJ1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000440354; ENSP00000391239; ENSG00000132669.
UCSCiuc010gcu.3. human.

Organism-specific databases

HGNCiHGNC:18750. RIN2.
OpenTargetsiENSG00000132669.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2320. Eukaryota.
ENOG410ZZW5. LUCA.
GeneTreeiENSGT00530000063053.

Miscellaneous databases

ChiTaRSiRIN2. human.

Gene expression databases

BgeeiENSG00000132669.
ExpressionAtlasiE7EPJ1. baseline and differential.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000159. RA_dom.
IPR000980. SH2.
IPR029071. Ubiquitin-rel_dom.
IPR003123. VPS9.
[Graphical view]
PfamiPF00788. RA. 1 hit.
PF02204. VPS9. 1 hit.
[Graphical view]
SMARTiSM00314. RA. 1 hit.
SM00167. VPS9. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS50200. RA. 1 hit.
PS51205. VPS9. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE7EPJ1_HUMAN
AccessioniPrimary (citable) accession number: E7EPJ1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: June 28, 2011
Last modified: November 30, 2016
This is version 43 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.