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Protein
Submitted name:

Sodium-dependent lysophosphatidylcholine symporter 1

Gene

MFSD2A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Sodium-dependent lysophosphatidylcholine symporter 1Imported
Gene namesi
Name:MFSD2AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000168389.17.
HGNCiHGNC:25897. MFSD2A.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei85 – 108HelicalSequence analysisAdd BLAST24
Transmembranei137 – 155HelicalSequence analysisAdd BLAST19
Transmembranei175 – 195HelicalSequence analysisAdd BLAST21
Transmembranei202 – 220HelicalSequence analysisAdd BLAST19
Transmembranei226 – 250HelicalSequence analysisAdd BLAST25
Transmembranei270 – 292HelicalSequence analysisAdd BLAST23
Transmembranei312 – 333HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168389.

PTM / Processingi

Proteomic databases

PeptideAtlasiE7EPI8.

Expressioni

Gene expression databases

BgeeiENSG00000168389.
ExpressionAtlasiE7EPI8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE7EPI8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4830. Eukaryota.
COG2211. LUCA.
GeneTreeiENSGT00390000005318.

Family and domain databases

InterProiView protein in InterPro
IPR036259. MFS_trans_sf.
SUPFAMiSSF103473. SSF103473. 2 hits.

Sequencei

Sequence statusi: Complete.

E7EPI8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTCFHVPYS ALTMFISTEQ TERDSATAYR MTVEVLGTVL GTAIQGQIVG
60 70 80 90 100
QADTPCFQDL NSSTVASQSA NHTHGTTSHR ETQKAYLLAA GVIVCIYIIC
110 120 130 140 150
AVILILGVRE QREPYEAQQS EPIAYFRGLR LVMSHGPYIK LITGFLFTSL
160 170 180 190 200
AFMLVEGNFV LFCTYTLGFR NEFQNLLLAI MLSATLTIPI WQWFLTRFGK
210 220 230 240 250
KTAVYVGISS AVPFLILVAL MESNLIITYA VAVAAGISVA AAFLLPWSML
260 270 280 290 300
PDVIDDFHLK QPHFHGTEPI FFSFYVFFTK FASGVSLGIS TLSLDFAGYQ
310 320 330 340 350
TRGCSQPERV KFTLNMLVTM APIVLILLGL LLFKMYPIDE ERRRQNKKAL
360 370
QALRDEASSS GCSETDSTEL ASIL
Length:374
Mass (Da):41,421
Last modified:June 28, 2011 - v2
Checksum:i2DB40AD074D1B429
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL663070 Genomic DNA. No translation available.
RefSeqiNP_001274737.1. NM_001287808.1.
UniGeneiHs.655177.

Genome annotation databases

EnsembliENST00000420632; ENSP00000391261; ENSG00000168389.
GeneIDi84879.
UCSCiuc010ojc.3. human.

Similar proteinsi

Entry informationi

Entry nameiE7EPI8_HUMAN
AccessioniPrimary (citable) accession number: E7EPI8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: June 28, 2011
Last modified: January 31, 2018
This is version 46 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported