Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Dynein heavy chain 9, axonemal

Gene

DNAH9

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Dynein heavy chain 9, axonemalImported
Gene namesi
Name:DNAH9Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000007174.17.
HGNCiHGNC:2953. DNAH9.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000007174.

PTM / Processingi

Proteomic databases

PaxDbiE7EP17.
PeptideAtlasiE7EP17.
PRIDEiE7EP17.

Expressioni

Gene expression databases

BgeeiENSG00000007174.
ExpressionAtlasiE7EP17. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE7EP17.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1865 – 2001AAAInterPro annotationAdd BLAST137
Domaini2143 – 2275AAAInterPro annotationAdd BLAST133
Domaini2470 – 2621AAAInterPro annotationAdd BLAST152
Domaini2817 – 2920AAAInterPro annotationAdd BLAST104

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili790 – 817Sequence analysisAdd BLAST28
Coiled coili3076 – 3110Sequence analysisAdd BLAST35
Coiled coili3289 – 3337Sequence analysisAdd BLAST49

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3595. Eukaryota.
COG5245. LUCA.
GeneTreeiENSGT00760000118964.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR035699. AAA_6.
IPR011704. ATPase_dyneun-rel_AAA.
IPR035706. DHC_D5.
IPR026983. DHC_fam.
IPR024743. Dynein_HC_stalk.
IPR024317. Dynein_heavy_chain_D4_dom.
IPR004273. Dynein_heavy_dom.
IPR013594. Dynein_heavy_dom-1.
IPR013602. Dynein_heavy_dom-2.
IPR027417. P-loop_NTPase.
PANTHERiPTHR10676. PTHR10676. 2 hits.
PfamiView protein in Pfam
PF07728. AAA_5. 1 hit.
PF12774. AAA_6. 1 hit.
PF12780. AAA_8. 1 hit.
PF12781. AAA_9. 1 hit.
PF08385. DHC_N1. 1 hit.
PF08393. DHC_N2. 1 hit.
PF03028. Dynein_heavy. 2 hits.
PF12777. MT. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 4 hits.
SUPFAMiSSF52540. SSF52540. 5 hits.

Sequencei

Sequence statusi: Complete.

E7EP17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLAEERAAL AAENADGEPG ADRRLRLLGT YVAMSLRPAA GAWERCAGSA
60 70 80 90 100
EAEQLLQAFL GRDAAEGPRP LLVVRPGPRG LAIRPGLEVG PESGLAGAKA
110 120 130 140 150
LFFLRTGPEP PGPDSFRGAV VCGDLPAAPL EHLAALFSEV VLPVLANEKN
160 170 180 190 200
RLNWPHMICE DVRRHAHSLQ CDLSVILEQV KGKTLLPLPA GSEKMEFADS
210 220 230 240 250
KSETVLDSID KSVIYAIESA VIKWSYQVQV VLKRESSQPL LQGENPTPKV
260 270 280 290 300
ELEFWKSRYE DLKYIYNQLR TITVRGMAKL LDKLQSSYFP AFKAMYRDVV
310 320 330 340 350
AALAEAQDIH VHLIPLQRHL EALENAEFPE VKPQLRPLLH VVCLIWATCK
360 370 380 390 400
SYRSPGRLTV LLQEICNLLI QQASNYLSPE DLLRSEVEES QRKLQVVSDT
410 420 430 440 450
LSFFKQEFQD RRENLHTYFK ENQEVKEWDF QSSLVFVRLD GFLGQLHVVE
460 470 480 490 500
GLLKTALDFH KLGKVEFSGV RGNALSQQVQ QMHEEFQEMY RLLSGSSSDC
510 520 530 540 550
LYLQSTDFEN DVSEFNQKVE DLDRRLGTIF IQAFDDAPGL EHAFKLLDIA
560 570 580 590 600
GNLLERPLVA RDTSDKYLVL IQMFNKDLDA VRMIYSQHVQ EEAELGFSPV
610 620 630 640 650
HKNMPTVAGG LRWAQELRQR IQGPFSNFGR ITHPCMESAE GKRMQQKYED
660 670 680 690 700
MLSLLEKYET RLYEDWCRTV SEKSQYNLSQ PLLKRDPETK EITINFNPQL
710 720 730 740 750
ISVLKEMSYL EPREMKHMPE TAAAMFSSRD FYRQLVANLE LMANWYNKVM
760 770 780 790 800
KTLLEVEFPL VEEELQNIDL RLRAAEETLN WKTEGICDYV TEITSSIHDL
810 820 830 840 850
EQRIQKTKDN VEEIQNIMKT WVTPIFKTKD GKRESLLSLD DRHDRMEKYY
860 870 880 890 900
NLIKESGLKI HALVQENLGL FSADPTSNIW KTYVNSIDNL LLNGFFLAIE
910 920 930 940 950
CSLKYLLENT ECKAGLTPIF EAQLSLAIPE LVFYPSLESG VKGGFCDIVE
960 970 980 990 1000
GLITSIFRIP SLVPRLSPQN GSPHYQVDLD GIPDLANMRR TLMERVQRMM
1010 1020 1030 1040 1050
GLCCGYQSTF SQYSYLYVED RKEVLGQFLL YGHILTPEEI EDHVEDGIPE
1060 1070 1080 1090 1100
NPPLLSQFKV QIDSYETLYE EVCRLEPIKV FDGWMKIDIR PFKASLLNII
1110 1120 1130 1140 1150
KRWSLLFKQH LVDHVTHSLA NLDAFIKKSE SGLLKKVEKG DFQGLVEIMG
1160 1170 1180 1190 1200
HLMAVKERQS NTDEMFEPLK QTIELLKTYE QELPETVFKQ LEELPEKWNN
1210 1220 1230 1240 1250
IKKVAITVKQ QVAPLQANEV TLLRQRCTAF DAEQQQFWEQ FHKEAPFRFD
1260 1270 1280 1290 1300
SIHPHQMLDA RHIEIQQMES TMASISESAS LFEVNVPDYK QLRQCRKEVC
1310 1320 1330 1340 1350
QLKELWDTIG MVTSSIHAWE TTPWRNINVE AMELECKQFA RHIRNLDKEV
1360 1370 1380 1390 1400
RAWDAFTGLE STVWNTLSSL RAVAELQNPA IRERHWRQLM QATGVSFTMD
1410 1420 1430 1440 1450
QDTTLAHLLQ LQLHHYEDEV RGIVDKAAKE MGMEKTLKEL QTTWAGMEFQ
1460 1470 1480 1490 1500
YEPHPRTNVP LLCSDEDLIE VLEDNQVQLQ NLVMSKYVAF FLEEVSGWQK
1510 1520 1530 1540 1550
KLSTVDAVIS IWFEVQRTWT HLESIFTGSE DIRAQLPQDS KRFEGIDIDF
1560 1570 1580 1590 1600
KELAYDAQKI PNVVQTTNKP GLYEKLEDIQ GRLCLCEKAL AEYLDTKRLA
1610 1620 1630 1640 1650
FPRFYFLSSS DLLDILSNGT APQQVQRHLS KLFDNMAKMR FQLDASGEPT
1660 1670 1680 1690 1700
KTSLGMYSKE EEYVAFSEPC DCSGQVEIWL NHVLGHMKAT VRHEMTEGVT
1710 1720 1730 1740 1750
AYEEKPREQW LFDHPAQVAL TCTQIWWTTE VGMAFARLEE GYESAMKDYY
1760 1770 1780 1790 1800
KKQVAQLKTL ITMLIGQLSK GDRQKIMTIC TIDVHARDVV AKMIAQKVDN
1810 1820 1830 1840 1850
AQAFLWLSQL RHRWDDEVKH CFANICDAQF LYSYEYLGNT PRLVITPLTD
1860 1870 1880 1890 1900
RCYITLTQSL HLTMSGAPAG PAGTGKTETT KDLGRALGIL VYVFNCSEQM
1910 1920 1930 1940 1950
DYKSCGNIYK GLAQTGAWGC FDEFNRISVE VLSVVAVQVK SIQDAIRDKK
1960 1970 1980 1990 2000
QWFSFLGEEI SLNPSVGIFI TMNPGYAGRT ELPENLKSLF RPCAMVVPDF
2010 2020 2030 2040 2050
ELICEIMLVA EGFIEAQSLA RKFITLYQLC KELLSKQDHY DWGLRAIKSV
2060 2070 2080 2090 2100
LVVAGSLKRG DPDRPEDQVL MRSLRDFNIP KIVTDDMPIF MGLIGDLFPA
2110 2120 2130 2140 2150
LDVPRRRDPN FEALVRKAIV DLKLQAEDNF VLKVVQLEEL LAVRHSVFVV
2160 2170 2180 2190 2200
GGAGTGKSQV LRSLHKTYQI MKRRPVWTDL NPKAVTNDEL FGIINPATGE
2210 2220 2230 2240 2250
WKDGLFSSIM RELANITHDG PKWILLDGDI DPMWIESLNT VMDDNKVLTL
2260 2270 2280 2290 2300
ASNERIPLNP TMKLLFEISH LRTATPATVS RAGILYINPA DLGWNPPVSS
2310 2320 2330 2340 2350
WIEKREIQTE RANLTILFDK YLPTCLDTLR TRFKKIIPIP EQSMVQMVCH
2360 2370 2380 2390 2400
LLECLLTTED IPADCPKEIY EHYFVFAAIW AFGGAMVQDQ LVDYRAEFSK
2410 2420 2430 2440 2450
WWLTEFKTVK FPSQGTIFDY YIDPETKKFE PWSKLVPQFE FDPEMPLQAC
2460 2470 2480 2490 2500
LVHTSETIRV CYFMERLMAR QRPVMLVGTA GTGKSVLVGA KLASLDPEAY
2510 2520 2530 2540 2550
LVKNVPFNYY TTSAMLQAVL EKPLEKKAGR NYGPPGNKKL IYFIDDMNMP
2560 2570 2580 2590 2600
EVDAYGTVQP HTIIRQHLDY GHWYDRSKLS LKEITNVQYV SCMNPTAGSF
2610 2620 2630 2640 2650
TINPRLQRHF SVFVLSFPGA DALSSIYSII LTQHLKLGNF PASLQKSIPP
2660 2670 2680 2690 2700
LIDLALAFHQ KIATTFLPTG IKFHYIFNLR DFANIFQGIL FSSVECVKST
2710 2720 2730 2740 2750
WDLIRLYLHE SNRVYRDKMV EEKDFDLFDK IQTEVLKKTF DDIEDPVEQT
2760 2770 2780 2790 2800
QSPNLYCHFA NGIGEPKYMP VQSWELLTQT LVEALENHNE VNTVMDLVLF
2810 2820 2830 2840 2850
EDAMRHVCHI NRILESPRGN ALLVGVGGSG KQSLTRLAAF ISSMDVFQIT
2860 2870 2880 2890 2900
LRKGYQIQDF KMDLASLCLK AGVKNLNTVF LMTDAQVADE RFLVLINDLL
2910 2920 2930 2940 2950
ASGEIPDLYS DDEVENIISN VRNEVKSQGL VDNRENCWKF FIDRIRRQLK
2960 2970 2980 2990 3000
VTLCFSPVGN KLRVRSRKFP AIVNCTAIHW FHEWPQQALE SVSLRFLQNT
3010 3020 3030 3040 3050
EGIEPTVKQS ISKFMAFVHT SVNQTSQSYL SNEQRYNYTT PKSFLEFIRL
3060 3070 3080 3090 3100
YQSLLHRHRK ELKCKTERLE NGLLKLHSTS AQVDDLKAKL AAQEVELKQK
3110 3120 3130 3140 3150
NEDADKLIQV VGVETDKVSR EKAMADEEEQ KVAVIMLEVK QKQKDCEEDL
3160 3170 3180 3190 3200
AKAEPALTAA QAALNTLNKT NLTELKSFGS PPLAVSNVSA AVMVLMAPRG
3210 3220 3230 3240 3250
RVPKDRSWKA AKVTMAKVDG FLDSLINFNK ENIHENCLKA IRPYLQDPEF
3260 3270 3280 3290 3300
NPEFVATKSY AAAGLCSWVI NIVRFYEVFC DVEPKRQALN KATADLTAAQ
3310 3320 3330 3340 3350
EKLAAIKAKI AHLNENLAKL TARFEKATAD KLKCQQEAEV TAVTISLANR
3360 3370 3380 3390 3400
LVGGLASENV RWADAVQNFK QQERTLCGDI LLITAFISYL GFFTKKYRQS
3410 3420 3430 3440 3450
LLDRTWRPYL SQLKTPIPVT PALDPLRMLM DDADVAAWQN EGLPADRMSV
3460 3470 3480 3490 3500
ENATILINCE RWPLMVDPQL QGIKWIKNKY GEDLRVTQIG QKGYLQIIEQ
3510 3520 3530 3540 3550
ALEAGAVVLI ENLEESIDPV LGPLLGREVI KKGRFIKIGD KECEYNPKFR
3560 3570 3580 3590 3600
LILHTKLANP HYQPELQAQA TLINFTVTRD GLEDQLLAAV VSMERPDLEQ
3610 3620 3630 3640 3650
LKSDLTKQQN GFKITLKTLE DSLLSRLSSA SGNFLGETVL VENLEITKQT
3660 3670 3680 3690 3700
AAEVEKKVQE AKVTEVKINE AREHYRPAAA RASLLYFIMN DLSKIHPMYQ
3710 3720 3730 3740 3750
FSLKAFSIVF QKAVERAAPD ESLRERVANL IDSITFSVYQ YTIRGLFECD
3760 3770 3780 3790 3800
KLTYLAQLTF QILLMNREVN AVELDFLLRS PVQTGTASPV EFLSHQAWGA
3810 3820 3830 3840 3850
VKVLSSMEEF SNLDRDIEGS AKSWKKFVES ECPEKEKLPQ EWKNKTALQR
3860 3870 3880 3890 3900
LCMLRAMRPD RMTYALRDFV EEKLGSKYVV GRALDFATSF EESGPATPMF
3910 3920 3930 3940 3950
FILSPGVDPL KDVESQGRKL GYTFNNQNFH NVSLGQGQEV VAEAALDLAA
3960 3970 3980 3990 4000
KKGHWVILQD TLEMCSRETE FKSILFALCY FHAVVAERRK FGPQGWNRSY
4010 4020 4030 4040 4050
PFNTGDLTIS VNVLYNFLEA NAKVPYDDLR YLFGEIMYGG HITDDWDRRL
4060 4070 4080 4090 4100
CRTYLGEFIR PEMLEGELSL APGFPLPGNM DYNGYHQYID AELPPESPYL
4110 4120 4130 4140 4150
YGLHPNAEIG FLTQTSEKLF RTVLELQPRD SQARDGAGAT REEKVKALLE
4160 4170 4180 4190 4200
EILERVTDEF NIPELMAKVE ERTPYIVVAF QECGRMNILT REIQRSLREL
4210 4220 4230 4240 4250
ELGLKGELTM TSHMENLQNA LYFDMVPESW ARRAYPSTAG LAAWFPDLLN
4260 4270 4280 4290 4300
RIKELEAWTG DFTMPSTVWL TGFFNPQSFL TAIMQSTARK NEWPLDQMAL
4310 4320 4330 4340 4350
QCDMTKKNRE EFRSPPREGA YIHGLFMEGA CWDTQAGIIT EAKLKDLTPP
4360 4370 4380 4390 4400
MPVMFIKAIP ADKQDCRSVY SCPVYKTSQR GPTYVWTFNL KTKENPSKWV
4410
LAGVALLLQI
Length:4,410
Mass (Da):503,346
Last modified:March 8, 2011 - v1
Checksum:i3D9C006A8CD409C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005209 Genomic DNA. No translation available.
AC005410 Genomic DNA. No translation available.
AC005701 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000454412; ENSP00000414874; ENSG00000007174.
UCSCiuc060bho.1. human.

Similar proteinsi

Entry informationi

Entry nameiE7EP17_HUMAN
AccessioniPrimary (citable) accession number: E7EP17
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: October 25, 2017
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported