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Protein
Submitted name:

Alpha-adducin

Gene

ADD1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-adducinImported
Gene namesi
Name:ADD1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000087274.16
HGNCiHGNC:243 ADD1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000087274

PTM / Processingi

Proteomic databases

MaxQBiE7ENY0
PeptideAtlasiE7ENY0
PRIDEiE7ENY0

Expressioni

Gene expression databases

BgeeiENSG00000087274
ExpressionAtlasiE7ENY0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE7ENY0
SMRiE7ENY0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini147 – 329Aldolase_IIInterPro annotationAdd BLAST183

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili603 – 627Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3699 Eukaryota
COG0235 LUCA
GeneTreeiENSGT00390000016462

Family and domain databases

Gene3Di3.40.225.10, 1 hit
InterProiView protein in InterPro
IPR027766 ADD1
IPR001303 Aldolase_II/adducin_N
IPR036409 Aldolase_II/adducin_N_sf
PANTHERiPTHR10672:SF4 PTHR10672:SF4, 1 hit
PfamiView protein in Pfam
PF00596 Aldolase_II, 1 hit
SMARTiView protein in SMART
SM01007 Aldolase_II, 1 hit
SUPFAMiSSF53639 SSF53639, 1 hit

Sequencei

Sequence statusi: Complete.

E7ENY0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGDSRAAVV TSPPPTTAPH KERYFDRVDE NNPEYLRERN MAPDLRQDFN
60 70 80 90 100
MMEQKKRVSM ILQSPAFCEE LESMIQEQFK KGKNPTGLLA LQQIADFMTT
110 120 130 140 150
NVPNVYPAAP QGGMAALNMS LGMVTPVNDL RGSDSIAYDK GEKLLRCKLA
160 170 180 190 200
AFYRLADLFG WSQLIYNHIT TRVNSEQEHF LIVPFGLLYS EVTASSLVKI
210 220 230 240 250
NLQGDIVDRG STNLGVNQAG FTLHSAIYAA RPDVKCVVHI HTPAGAAVSA
260 270 280 290 300
MKCGLLPISP EALSLGEVAY HDYHGILVDE EEKVLIQKNL GPKSKVLILR
310 320 330 340 350
NHGLVSVGES VEEAFYYIHN LVVACEIQVR TLASAGGPDN LVLLNPEKYK
360 370 380 390 400
AKSRSPGSPV GEGTGSPPKW QIGEQEFEAL MRMLDNLGYR TGYPYRYPAL
410 420 430 440 450
REKSKKYSDV EVPASVTGYS FASDGDSGTC SPLRHSFQKQ QREKTRWLNS
460 470 480 490 500
GRGDEASEEG QNGSSPKSKT KVWTNITHDH VKPLLQSLSS GVCVPSCITN
510 520 530 540 550
CLWTKEDGHR TSTSAVPNLF VPLNTNPKEV QEMRNKIREQ NLQDIKTAGP
560 570 580 590 600
QSQVLCGVVM DRSLVQGELV TASKAIIEKE YQPHVIVSTT GPNPFTTLTD
610 620 630 640 650
RELEEYRREV ERKQKGSEEN LDEAREQKEK SPPDQPAVPH PPPSTPIKLE
660
EAGDGCAREY LLP
Length:663
Mass (Da):73,404
Last modified:March 8, 2011 - v1
Checksum:i6FE8CCBF6FAB8824
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121750 Genomic DNA No translation available.
AL390065 Genomic DNA No translation available.
BX465861 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000503455; ENSP00000423024; ENSG00000087274
UCSCiuc062usb.1 human

Similar proteinsi

Entry informationi

Entry nameiE7ENY0_HUMAN
AccessioniPrimary (citable) accession number: E7ENY0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: April 25, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health