E7EN68 (E7EN68_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Histone-lysine N-methyltransferase Ensembl ENSP00000403145

Gene names

Name:

SETMAR Ensembl ENSP00000403145

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000403145

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	545 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000403145

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA integration Inferred from electronic annotation. Source: InterPro transposition, DNA-mediated Inferred from electronic annotation. Source: InterPro
Cellular_component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro transposase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E7EN68 [UniParc]. Last modified March 8, 2011. Version 1. Checksum: 8F570F8A67A495C7	FASTA	545	62,124
	10 20 30 40 50 60 MFAEAAKTTR PCGMAEFKEK PEAPTEQLDV ACGQENLPVG AWPPGAAPAP FQYTPDHVVG 70 80 90 100 110 120 PGADIDPTQI TFPGCICVKT PCLPGTCSCL RHGENYDDNS CLRDIGSGGK YAEPVFECNV 130 140 150 160 170 180 LCRCSDHCRN RVVQKGLQFH FQVFKTHKKG WGLRTLEFIP KGSSLYCPVE KSNISCGNEK 190 200 210 220 230 240 EPSMCGSAPS VFPSCKRLTL ETMKMMLDKK QIRAIFLFEF KMGRKAAETT RNINNAFGPG 250 260 270 280 290 300 TANERTVQWW FKKFCKGDES LEDEERSGRP SEVDNDQLRA IIEADPLTTT REVAEELNVN 310 320 330 340 350 360 HSTVVRHLKQ IGKVKKLDKW VPHELTENQK NRRFEVSSSL ILRNHNEPFL DRIVTCDEKW 370 380 390 400 410 420 ILYDNRRRSA QWLDQEEAPK HFPKPILHPK KVMVTIWWSA AGLIHYSFLN PGETITSEKY 430 440 450 460 470 480 AQEIDEMNQK LQRLQLALVN RKGPILLHDN ARPHVAQPTL QKLNELGYEV LPHPPYSPDL 490 500 510 520 530 540 LPTNYHVFKH LNNFLQGKRF HNQQDAENAF QEFVESQSTD FYATGINQLI SRWQKCVDCN GSYFD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence, annotation and analysis of human chromosome 3." Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A. Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC023483 Genomic DNA. No translation available. AC034191 Genomic DNA. No translation available.
IPI	IPI00925837.
RefSeq	NP_001230652.1. NM_001243723.1.
UniGene	Hs.475300.
3D structure databases
ProteinModelPortal	E7EN68.
SMR	E7EN68. Positions 25-162, 208-545.
ModBase	Search...
Proteomic databases
PRIDE	E7EN68.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000425863; ENSP00000403145; ENSG00000170364.
GeneID	6419.
KEGG	hsa:6419.
UCSC	uc011asq.2. human.
Organism-specific databases
CTD	6419.
HGNC	HGNC:10762. SETMAR.
GenAtlas	Search...
Phylogenomic databases
KO	K11433.
Gene expression databases
ArrayExpress	E7EN68.
Bgee	E7EN68.
Family and domain databases
InterPro	IPR007728. Pre-SET_dom. IPR003606. Pre-SET_Zn-bd_sub. IPR001888. Transposase_1. IPR002492. Transposase_Tc1-like. [Graphical view]
Pfam	PF01498. HTH_Tnp_Tc3_2. 1 hit. PF05033. Pre-SET. 1 hit. PF01359. Transposase_1. 1 hit. [Graphical view]
SMART	SM00468. PreSET. 1 hit. [Graphical view]
PROSITE	PS50867. PRE_SET. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	6419.
NextBio	24930.

Entry information

Entry name

E7EN68_HUMAN

Accession

Primary (citable) accession number: E7EN68

Entry history

Integrated into UniProtKB/TrEMBL:	March 8, 2011
Last sequence update:	March 8, 2011
Last modified:	May 1, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.