E7EMR3 (E7EMR3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Latrophilin-3 Ensembl ENSP00000424120

Gene names

Name:

LPHN3 Ensembl ENSP00000424120

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000424120

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1231 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities	Contains 1 GPS domain. SAAS SAAS000203 Contains 1 olfactomedin-like domain. SAAS SAAS003112
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000424120

Ontologies

Keywords
Cellular component	Cell membrane SAAS SAAS000203 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS000203
Molecular function	G-protein coupled receptor SAAS SAAS001879 Receptor Transducer
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	neuropeptide signaling pathway Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E7EMR3 [UniParc]. Last modified March 8, 2011. Version 1. Checksum: 60BADA8FE90FFCE1	FASTA	1,231	138,131
	10 20 30 40 50 60 MWPSQLLIFM MLLAPIIHAF SRAPIPMAVV RRELSCESYP IELRCPGTDV IMIESANYGR 70 80 90 100 110 120 TDDKICDSDP AQMENIRCYL PDAYKIMSQR CNNRTQCAVV AGPDVFPDPC PGTYKYLEVQ 130 140 150 160 170 180 YECVPYKVEQ KVFLCPGLLK GVYQSEHLFE SDHQSGAWCK DPLQASDKIY YMPWTPYRTD 190 200 210 220 230 240 TLTEYSSKDD FIAGRPTTTY KLPHRVDGTG FVVYDGALFF NKERTRNIVK FDLRTRIKSG 250 260 270 280 290 300 EAIIANANYH DTSPYRWGGK SDIDLAVDEN GLWVIYATEQ NNGKIVISQL NPYTLRIEGT 310 320 330 340 350 360 WDTAYDKRSA SNAFMICGIL YVVKSVYEDD DNEATGNKID YIYNTDQSKD SLVDVPFPNS 370 380 390 400 410 420 YQYIAAVDYN PRDNLLYVWN NYHVVKYSLD FGPLDSRSGQ AHHGQVSYIS PPIHLDSELE 430 440 450 460 470 480 RPSVKDISTT GPLGMGSTTT STTLRTTTLS PGRSTTPSVS GRRNRSTSTP SPAVEVLDDM 490 500 510 520 530 540 TTHLPSASSQ IPALEESCEA VEAREIMWFK TRQGQIAKQP CPAGTIGVST YLCLAPDGIW 550 560 570 580 590 600 DPQGPDLSNC SSPWVNHITQ KLKSGETAAN IARELAEQTR NHLNAGDITY SVRAMDQLVG 610 620 630 640 650 660 LLDVQLRNLT PGGKDSAARS LNKLQKRERS CRAYVQAMVE TVNNLLQPQA LNAWRDLTTS 670 680 690 700 710 720 DQLRAATMLL HTVEESAFVL ADNLLKTDIV RENTDNIKLE VARLSTEGNL EDLKFPENMG 730 740 750 760 770 780 HGSTIQLSAN TLKQNGRNGE IRVAFVLYNN LGPYLSTENA SMKLGTEALS TNHSVIVNSP 790 800 810 820 830 840 VITAAINKEF SNKVYLADPV VFTVKHIKQS EENFNPNCSF WSYSKRTMTG YWSTQGCRLL 850 860 870 880 890 900 TTNKTHTTCS CNHLTNFAVL MAHVEVKHSD AVHDLLLDVI TWVGILLSLV CLLICIFTFC 910 920 930 940 950 960 FFRGLQSDRN TIHKNLCISL FVAELLFLIG INRTDQPIAC AVFAALLHFF FLAAFTWMFL 970 980 990 1000 1010 1020 EGVQLYIMLV EVFESEHSRR KYFYLVGYGM PALIVAVSAA VDYRSYGTDK VCWLRLDTYF 1030 1040 1050 1060 1070 1080 IWSFIGPATL IIMLNVIFLG IALYKMFHHT AILKPESGCL DNIKSWVIGA IALLCLLGLT 1090 1100 1110 1120 1130 1140 WAFGLMYINE STVIMAYLFT IFNSLQGMFI FIFHCVLQKK VRKEYGKCLR THCCSGKSTE 1150 1160 1170 1180 1190 1200 SSIGSGKTSG SRTPGRYSTG SQSRIRRMWN DTVRKQSESS FITGDINSSA SLNREPYRET 1210 1220 1230 SMGVKLNIAY QIGASEQCQG YKCHGYSTTE W

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC007511 Genomic DNA. No translation available. AC020741 Genomic DNA. No translation available. AC092643 Genomic DNA. No translation available. AC092663 Genomic DNA. No translation available. AC092668 Genomic DNA. No translation available. AC096723 Genomic DNA. No translation available. AC104813 Genomic DNA. No translation available. AC108161 Genomic DNA. No translation available.
IPI	IPI01019069.
3D structure databases
SMR	E7EMR3. Positions 25-129, 498-854.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000506700; ENSP00000424120; ENSG00000150471.
Organism-specific databases
HGNC	HGNC:20974. LPHN3.
GenAtlas	Search...
Family and domain databases
InterPro	IPR022624. DUF3497. IPR017981. GPCR_2-like. IPR001879. GPCR_2_extracellular_dom. IPR003924. GPCR_2_latrophilin. IPR015630. GPCR_2_latrophilin3. IPR003334. GPCR_2_latrophilin_rcpt_C. IPR000832. GPCR_2_secretin-like. IPR017983. GPCR_2_secretin-like_CS. IPR000203. GPS_dom. IPR000922. Lectin_gal-bd_dom. IPR003112. Olfac-like. [Graphical view]
PANTHER	PTHR12011:SF60. PTHR12011:SF60. 1 hit.
Pfam	PF00002. 7tm_2. 1 hit. PF12003. DUF3497. 1 hit. PF02140. Gal_Lectin. 1 hit. PF01825. GPS. 1 hit. PF02793. HRM. 1 hit. PF02354. Latrophilin. 1 hit. PF02191. OLF. 1 hit. [Graphical view]
PRINTS	PR00249. GPCRSECRETIN. PR01444. LATROPHILIN.
SMART	SM00303. GPS. 1 hit. SM00008. HormR. 1 hit. SM00284. OLF. 1 hit. [Graphical view]
PROSITE	PS00650. G_PROTEIN_RECEP_F2_2. 1 hit. PS50227. G_PROTEIN_RECEP_F2_3. 1 hit. PS50261. G_PROTEIN_RECEP_F2_4. 1 hit. PS50221. GPS. 1 hit. PS51132. OLF. 1 hit. PS50228. SUEL_LECTIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	LPHN3. human.
NextBio	35499491.

Entry information

Entry name

E7EMR3_HUMAN

Accession

Primary (citable) accession number: E7EMR3

Entry history

Integrated into UniProtKB/TrEMBL:	March 8, 2011
Last sequence update:	March 8, 2011
Last modified:	May 1, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.