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Protein
Submitted name:

Dual-specificity tyrosine-phosphorylation-regulated kinase 1A

Gene

DYRK1A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Dual-specificity tyrosine-phosphorylation-regulated kinase 1AImported
Gene namesi
Name:DYRK1AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 21

Organism-specific databases

HGNCiHGNC:3091. DYRK1A.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000157540.

PTM / Processingi

Proteomic databases

MaxQBiE7EMI5.
PaxDbiE7EMI5.
PeptideAtlasiE7EMI5.

Expressioni

Gene expression databases

BgeeiENSG00000157540.
ExpressionAtlasiE7EMI5. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000381932.

Structurei

3D structure databases

ProteinModelPortaliE7EMI5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0667. Eukaryota.
ENOG410XPET. LUCA.
GeneTreeiENSGT00760000119032.

Family and domain databases

InterProiIPR028318. DYRK1A.
[Graphical view]
PANTHERiPTHR24058:SF28. PTHR24058:SF28. 1 hit.

Sequencei

Sequence statusi: Fragment.

E7EMI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHTGGETSAC KPSSVRLAPS FSFHAAGLQM AGQMPHSHQY SDRRQPNISD
60 70 80 90 100
QQVSALSYSD QIQQPLTNQV MPDIVMLQRR MPQTFRDPAT APLRKLSVDL
110 120 130
IKTYKHINEV YYAKKKRRHQ QGQGDDSSHK K
Length:131
Mass (Da):14,876
Last modified:March 8, 2011 - v1
Checksum:iDAE0983D2B51A625
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei131Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001413 Genomic DNA. No translation available.
AP001421 Genomic DNA. No translation available.
AP001428 Genomic DNA. No translation available.
AP001437 Genomic DNA. No translation available.
KF457264 Genomic DNA. No translation available.
KF457265 Genomic DNA. No translation available.
KF510556 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000426672; ENSP00000412269; ENSG00000157540.
UCSCiuc062aay.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001413 Genomic DNA. No translation available.
AP001421 Genomic DNA. No translation available.
AP001428 Genomic DNA. No translation available.
AP001437 Genomic DNA. No translation available.
KF457264 Genomic DNA. No translation available.
KF457265 Genomic DNA. No translation available.
KF510556 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE7EMI5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000381932.

Proteomic databases

MaxQBiE7EMI5.
PaxDbiE7EMI5.
PeptideAtlasiE7EMI5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000426672; ENSP00000412269; ENSG00000157540.
UCSCiuc062aay.1. human.

Organism-specific databases

HGNCiHGNC:3091. DYRK1A.
OpenTargetsiENSG00000157540.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0667. Eukaryota.
ENOG410XPET. LUCA.
GeneTreeiENSGT00760000119032.

Miscellaneous databases

ChiTaRSiDYRK1A. human.

Gene expression databases

BgeeiENSG00000157540.
ExpressionAtlasiE7EMI5. baseline and differential.

Family and domain databases

InterProiIPR028318. DYRK1A.
[Graphical view]
PANTHERiPTHR24058:SF28. PTHR24058:SF28. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE7EMI5_HUMAN
AccessioniPrimary (citable) accession number: E7EMI5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: November 2, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.