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Protein
Submitted name:

Epididymis secretory protein Li 104

Gene

FABP4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywordsi

Biological processTransportUniRule annotation
LigandLipid-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Epididymis secretory protein Li 104Imported
Submitted name:
Fatty acid binding protein 4, adipocyteImported
Gene namesi
Name:FABP4Imported
Synonyms:HEL-S-104Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSG00000170323.
ExpressionAtlasiE7DVW4. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000256104.

Structurei

3D structure databases

SMRiE7DVW4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 24FABPInterPro annotationAdd BLAST18

Sequence similaritiesi

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4015. Eukaryota.
ENOG4111US8. LUCA.
KOiK08753.
OMAiGQEFDEI.
OrthoDBiEOG091G0QSV.
PhylomeDBiE7DVW4.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR033073. FABP4.
IPR000463. Fatty_acid-bd.
IPR031259. iLBP.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PANTHERiPTHR11955. PTHR11955. 1 hit.
PTHR11955:SF83. PTHR11955:SF83. 1 hit.
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PRINTSiPR00178. FATTYACIDBP.
SUPFAMiSSF50814. SSF50814. 1 hit.
PROSITEiPS00214. FABP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E7DVW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCDAFVGTWK LVSSENFDDY MKEVGVGFAT RKVAGMAKPN MIISVNGDVI
60 70 80 90 100
TIKSESTFKN TEISFILGQE FDEVTADDRK VKSTITLDGG VLVHVQKWDG
110 120 130
KSTTIKRKRE DDKLVVECVM KGVTSTRVYE RA
Length:132
Mass (Da):14,719
Last modified:March 8, 2011 - v1
Checksum:i819D788FF4BF7235
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ224319 mRNA. Translation: ACI46011.1.
HQ384160 Genomic DNA. Translation: ADU05469.1.
RefSeqiNP_001433.1. NM_001442.2.
UniGeneiHs.391561.

Genome annotation databases

GeneIDi2167.
KEGGihsa:2167.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ224319 mRNA. Translation: ACI46011.1.
HQ384160 Genomic DNA. Translation: ADU05469.1.
RefSeqiNP_001433.1. NM_001442.2.
UniGeneiHs.391561.

3D structure databases

SMRiE7DVW4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000256104.

Protocols and materials databases

DNASUi2167.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2167.
KEGGihsa:2167.

Organism-specific databases

CTDi2167.

Phylogenomic databases

eggNOGiKOG4015. Eukaryota.
ENOG4111US8. LUCA.
KOiK08753.
OMAiGQEFDEI.
OrthoDBiEOG091G0QSV.
PhylomeDBiE7DVW4.

Miscellaneous databases

ChiTaRSiFABP4. human.
GenomeRNAii2167.

Gene expression databases

BgeeiENSG00000170323.
ExpressionAtlasiE7DVW4. baseline and differential.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR033073. FABP4.
IPR000463. Fatty_acid-bd.
IPR031259. iLBP.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PANTHERiPTHR11955. PTHR11955. 1 hit.
PTHR11955:SF83. PTHR11955:SF83. 1 hit.
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PRINTSiPR00178. FATTYACIDBP.
SUPFAMiSSF50814. SSF50814. 1 hit.
PROSITEiPS00214. FABP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE7DVW4_HUMAN
AccessioniPrimary (citable) accession number: E7DVW4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: January 18, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.