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E7DN63

- BAMS_SOLLC

UniProt

E7DN63 - BAMS_SOLLC

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Protein

Beta-amyrin synthase

Gene

TTS1

Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Oxidosqualene cyclase converting oxidosqualene into beta-amyrin, generating five rings and eight asymmetric centers in a single transformation.1 Publication

Catalytic activityi

(3S)-2,3-epoxy-2,3-dihydrosqualene = beta-amyrin.1 Publication

GO - Molecular functioni

  1. intramolecular transferase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-17974.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-amyrin synthase (EC:5.4.99.39)
Alternative name(s):
Triterpenoid synthase 1
Short name:
SlTTS1
Gene namesi
Name:TTS1
OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
Taxonomic identifieri4081 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon
ProteomesiUP000004994: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 761761Beta-amyrin synthasePRO_0000413967Add
BLAST

Expressioni

Tissue specificityi

Expressed in the leaves and in the epidermal cells but not in the inner tissues of the fruit.1 Publication

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati148 – 18942PFTB 1Add
BLAST
Repeati513 – 55846PFTB 2Add
BLAST
Repeati590 – 63041PFTB 3Add
BLAST
Repeati639 – 68042PFTB 4Add
BLAST
Repeati701 – 74242PFTB 5Add
BLAST

Sequence similaritiesi

Belongs to the terpene cyclase/mutase family.Curated
Contains 5 PFTB repeats.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

InParanoidiE7DN63.
KOiK15813.

Family and domain databases

Gene3Di1.50.10.20. 2 hits.
InterProiIPR001330. Prenyltrans.
IPR018333. Squalene_cyclase.
IPR002365. Terpene_synthase_CS.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view]
PfamiPF00432. Prenyltrans. 1 hit.
[Graphical view]
SUPFAMiSSF48239. SSF48239. 2 hits.
TIGRFAMsiTIGR01787. squalene_cyclas. 1 hit.
PROSITEiPS01074. TERPENE_SYNTHASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E7DN63-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MWKLKIAEGQ NGPYLYSTNN YVGRQTWEFD PNGGTIEERA KIEEARQQFW
60 70 80 90 100
NNRYKVKPSS DLLWRIQFLG EKNFKQKIPA VKVEEGEEIS HEVATIALHR
110 120 130 140 150
AVNFFSALQA TDGHWPAENA GPLFFLPPLV MCMYITGHLN TVFPAEHRKE
160 170 180 190 200
ILRYIYCHQN EDGGWGLHIE GHSTMFCTAL SYICMRILGE GPDGGVNNAC
210 220 230 240 250
ARARKWILDH GSVTAIPSWG KTWLSILGVF EWIGTNPMPP EFWILPSFLP
260 270 280 290 300
VHPAKMWCYC RMVYMPMSYL YGKRFVGPIT PLILQLREEL YDRPYDEINW
310 320 330 340 350
KKVRHVCAKE DLYYPHPLVQ DLMWDSLYIC TEPLLTRWPF NKLRNKALEV
360 370 380 390 400
TMKHIHYEDE NSRYITIGCV EKVLCMLACW VEDPNGDYFK KHLARIPDYL
410 420 430 440 450
WVAEDGMKMQ SFGSQEWDTG FAIQALLASE MNDEIADTLR KGHDFIKQSQ
460 470 480 490 500
VTNNPSGDFK GMYRHISKGS WTFSDQDHGW QVSDCTAEAL KCCLLLSTMP
510 520 530 540 550
RELVGQAMEP GRLYDSVNVV LSLQSKNGGL AAWEPAGASE YLELLNPTEF
560 570 580 590 600
FADIVIEHEY VECTASSIQA LVLFKKLYPG HRTKEINIFI DNAVKYLEDV
610 620 630 640 650
QMPDGSWYGN WGVCFTYGSW FALGGLVAAG KSYNNSAAVR KGVEFLLRTQ
660 670 680 690 700
RSDGGWGESY RSCPDKVYRE LETNDSNLVQ TAWALMGLIH SGQADRDPKP
710 720 730 740 750
LHRAAKLLIN SQMEDGDFPQ QEITGVFMKN CMLHYAAYRN IYPLWGLAEY
760
RKNVLLPLEN N
Length:761
Mass (Da):87,248
Last modified:March 8, 2011 - v1
Checksum:i313628BF40BA5428
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ266579 mRNA. Translation: ADU52574.1.
RefSeqiNP_001234604.1. NM_001247675.1.
UniGeneiLes.25599.

Genome annotation databases

GeneIDi100529102.
KEGGisly:100529102.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ266579 mRNA. Translation: ADU52574.1 .
RefSeqi NP_001234604.1. NM_001247675.1.
UniGenei Les.25599.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100529102.
KEGGi sly:100529102.

Phylogenomic databases

InParanoidi E7DN63.
KOi K15813.

Enzyme and pathway databases

BioCyci MetaCyc:MONOMER-17974.

Family and domain databases

Gene3Di 1.50.10.20. 2 hits.
InterProi IPR001330. Prenyltrans.
IPR018333. Squalene_cyclase.
IPR002365. Terpene_synthase_CS.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view ]
Pfami PF00432. Prenyltrans. 1 hit.
[Graphical view ]
SUPFAMi SSF48239. SSF48239. 2 hits.
TIGRFAMsi TIGR01787. squalene_cyclas. 1 hit.
PROSITEi PS01074. TERPENE_SYNTHASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Two oxidosqualene cyclases responsible for biosynthesis of tomato fruit cuticular triterpenoids."
    Wang Z., Guhling O., Yao R., Li F., Yeats T., Rose J., Jetter R.
    Plant Physiol. 155:540-552(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, CATALYTIC ACTIVITY, TISSUE SPECIFICITY.
    Strain: cv. MicroTom.

Entry informationi

Entry nameiBAMS_SOLLC
AccessioniPrimary (citable) accession number: E7DN63
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 16, 2011
Last sequence update: March 8, 2011
Last modified: October 29, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3