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E7D8R1

- E7D8R1_CLOPF

UniProt

E7D8R1 - E7D8R1_CLOPF

Protein
Submitted name:

Epsilon-toxin

Gene

etx

Organism
Clostridium perfringens D
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 15 (01 Oct 2014)
      Sequence version 1 (08 Mar 2011)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei93 – 931PhosphateImported
    Binding sitei233 – 2331PhosphateImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Epsilon-toxinImported
    Gene namesi
    Name:etxImported
    OrganismiClostridium perfringens DImported
    Taxonomic identifieri107819 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3232 PotentialImportedAdd
    BLAST
    Chaini33 – 334302 PotentialImportedPRO_5000920962Add
    BLAST
    Chaini46 – 328283epsilon toxinImportedPRO_5000692029Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-8199207.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3ZJXX-ray2.40A/B/C/D47-328[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    SignalImported

    Family and domain databases

    Gene3Di2.170.15.10. 2 hits.
    InterProiIPR023307. Aerolysin-like_beta_cmplx_dom.
    IPR009209. Epsilon_toxin.
    IPR004991. ETX_MTX2.
    [Graphical view]
    PfamiPF03318. ETX_MTX2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF026587. Epsilon_toxin. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    E7D8R1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKKNLVKSLA IASAVISIYS IVNIVSPTNV IAKEISNTVS NEMSKKASYD    50
    NVDTLIEKGR YNTKYNYLKR MEKYYPNAMA YFDKVTINPQ GNDFYINNPK 100
    VELDGEPSMN YLEDVYVGKA LLTNDTQQEQ KLKSQSFTCK NTDTVTATTT 150
    HTVGTSIQAT AKFTVPFNET GVSLTTSYSF ANTNTNTNSK EITHNVPSQD 200
    ILVPANTTVE VIAYLKKVNV KGNVKLVGQV SGSEWGEIPS YLAFPRDGYK 250
    FSLSDTVNKS DLNEDGTINI NGKGNYSAVM GDELIVKVRN LNTNNVQEYV 300
    IPVDKKEKSN DSNIVKYRSL SIKAPGIKAE AAAK 334
    Length:334
    Mass (Da):36,862
    Last modified:March 8, 2011 - v1
    Checksum:i8C80F71E3E30B0B6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei334 – 3341Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HQ179546 Genomic DNA. Translation: ADU04573.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HQ179546 Genomic DNA. Translation: ADU04573.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3ZJX X-ray 2.40 A/B/C/D 47-328 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-8199207.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 2.170.15.10. 2 hits.
    InterProi IPR023307. Aerolysin-like_beta_cmplx_dom.
    IPR009209. Epsilon_toxin.
    IPR004991. ETX_MTX2.
    [Graphical view ]
    Pfami PF03318. ETX_MTX2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF026587. Epsilon_toxin. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Fusion of Clostridium perfringens type D and B epsilon and beta toxin genes and it's cloning in E. coli."
      Pilehchian Langroudi R., Aghaei Pour K., Shamsara M., Ghorashi S.A.
      Arch Razi Inst 66:1-10(2011)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: CWD CN 409Imported.
    2. "In silico fusion of epsilon and beta toxin genes of Clostridium perfringens types D and B."
      Pilehchian Langroudi R., Aghaei Pour K., Shamsara M., Ghorashi S.A.
      Iran. J. Biotechnol. 10:54-60(2012)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: CWD CN 409Imported.
    3. "Clostridium perfringens epsilon toxin H149A mutant as a platform for receptor binding studies."
      Bokori-Brown M., Kokkinidou M.C., Savva C.G., Fernandes da Costa S., Naylor C.E., Cole A.R., Moss D.S., Basak A.K., Titball R.W.
      Protein Sci. 22:650-659(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 47-328.

    Entry informationi

    Entry nameiE7D8R1_CLOPF
    AccessioniPrimary (citable) accession number: E7D8R1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 15 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3