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E7BJ57

- E7BJ57_HUMAN

UniProt

E7BJ57 - E7BJ57_HUMAN

Protein
Submitted name:

CCR5

Gene

CCR5

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
  1. Functioni

    GO - Molecular functioni

    1. chemokine receptor activity Source: InterPro

    GO - Biological processi

    1. chemotaxis Source: InterPro

    Keywords - Molecular functioni

    G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CCR5Imported
    Gene namesi
    Name:CCR5Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiE7BJ57.
    BgeeiE7BJ57.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000355. Chemokine_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view]
    PANTHERiPTHR24227. PTHR24227. 1 hit.
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00657. CCCHEMOKINER.
    PR00237. GPCRRHODOPSN.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    E7BJ57-1 [UniParc]FASTAAdd to Basket

    « Hide

    EPCQKINVKQ IAARLLPPLY SLVFIFGFVG NMLVILILIN CKRLKSMTDI    50
    YLLNLAISDL FFLLTVPFWA HYAAAQWDFG NTMCQLLTGL YFIGFFSGIF 100
    FIILLTIDRY LAVVHAVFAL KARTVTFGVV TSVITWVVAV FASLPGIIFT 150
    RSQKEGLHYT CSSHFP 166
    Length:166
    Mass (Da):18,708
    Last modified:March 8, 2011 - v1
    Checksum:i5A18D447A1770DBD
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei166 – 1661Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GQ121035 Genomic DNA. Translation: ADC94815.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GQ121035 Genomic DNA. Translation: ADC94815.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    GPCRDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    NextBioi 35499246.

    Gene expression databases

    ArrayExpressi E7BJ57.
    Bgeei E7BJ57.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000355. Chemokine_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view ]
    PANTHERi PTHR24227. PTHR24227. 1 hit.
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00657. CCCHEMOKINER.
    PR00237. GPCRRHODOPSN.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Prevalence of CCR5-d24 allele in different ethnic populations of India."
      Saxena S.K., Swamy M.L.A.
      Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BloodImported.

    Entry informationi

    Entry nameiE7BJ57_HUMAN
    AccessioniPrimary (citable) accession number: E7BJ57
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.