SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E7BGW8

- E7BGW8_NEIMW

UniProt

E7BGW8 - E7BGW8_NEIMW

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase IDH)
Gene
icd, NMAA_0720
Organism
Neisseria meningitidis serogroup A (strain WUE 2594)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei146 – 1461Substrate By similarity
Sitei256 – 2561Critical for catalysis By similarityUniRule annotation
Metal bindingi351 – 3511Magnesium or manganese By similarityUniRule annotation
Sitei421 – 4211Critical for catalysis By similarityUniRule annotation
Binding sitei548 – 5481Substrate By similarityUniRule annotation
Metal bindingi549 – 5491Magnesium or manganese By similarityUniRule annotation
Metal bindingi553 – 5531Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciNMEN942513:GLHV-801-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase IDH)Imported (EC:1.1.1.42Imported)
Gene namesi
Name:icdImported
Ordered Locus Names:NMAA_0720Imported
OrganismiNeisseria meningitidis serogroup A (strain WUE 2594)Imported
Taxonomic identifieri942513 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
ProteomesiUP000008638: Chromosome

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni133 – 1408Substrate binding By similarity

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

E7BGW8-1 [UniParc]FASTAAdd to Basket

« Hide

MTQKSTIVYT HTDEAPALAT QSLLPIVQAF ARHADIDVKT ADISLSGRIL    50
AAFPEYLTEA QRVPDALAEL GELVKQPDAN VIKLPNISAS VPQLTAAIKE 100
LQSKGFAVPD YPADPQTDEE KAVRERYDRI KGSAVNPVLR EGNSDRRAPK 150
AVKNFAKKNP HSMGAWAKDS KTHVATMQSG DFFHNEQSVT VPDATSVSIV 200
FTDKQGNKKE LRDPVALKAG EIIDATVMSK KALLAFLAEQ VKDAKAKGVL 250
FSLHMKATMM KVSDPIIFGH AVKVFFAPVF EKFGDKLAAA GVNVNNGFGN 300
LLANLDKLDA DTRAAVEAEI AAVYAANPDL AMVDSDKGIT NLHVPSDVIV 350
DASMPAMIRN SGRMWDKNGK AQDTKAVIPD SSYAGVYQAT IDFCREHGAF 400
DPTTMGTVPN VGLMAQAAEE YGSHNKTFEI EADGQVQVVD AAGKVLMQHD 450
VEAGDIWRMC QTKDDPVKDW VQLAVNRARL SNTPAVFWLD ENRPHDKSLL 500
AKVKAYLAEL DTNGLDIRVL APEEAAKFSL GRLKNGEDTI SVTGNVLRDY 550
LTDLFPILEL GTSAKMLSIV PLMNGGGMFE TGAGGSAPKH VQQFLEENHL 600
RWDSLGEFLA LAVSFEHLAQ KTGNAKAQVL ADTLDAATEK LLLNDKSPKR 650
KAGELDNRGS HFYLTLYWAQ ELAAQDKDAE LKAAFTPLAA ALTADEAKIV 700
AELSAVQGKA ADIGGYYAAN PEKAAQVMRP SVTFNQALNA L 741
Length:741
Mass (Da):80,077
Last modified:March 8, 2011 - v1
Checksum:i3786D2E2958212B5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FR774048 Genomic DNA. Translation: CBY90597.1.
RefSeqiYP_005891715.1. NC_017512.1.

Genome annotation databases

EnsemblBacteriaiCBY90597; CBY90597; NMAA_0720.
GeneIDi12408298.
KEGGinmw:NMAA_0720.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FR774048 Genomic DNA. Translation: CBY90597.1 .
RefSeqi YP_005891715.1. NC_017512.1.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBY90597 ; CBY90597 ; NMAA_0720 .
GeneIDi 12408298.
KEGGi nmw:NMAA_0720.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci NMEN942513:GLHV-801-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Whole-genome sequence of the transformable Neisseria meningitidis serogroup A strain WUE2594."
    Schoen C., Weber-Lehmann J., Blom J., Joseph B., Goesmann A., Strittmatter A., Frosch M.
    J. Bacteriol. 193:2064-2065(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WUE 2594Imported.
  2. ""Whole-genome sequence of the transformable Neisseria meningitidis serogroup A strain WUE2594"."
    Schoen C., Weber-Lehmann J., Blom J., Joseph B., Goesmann A., Strittmatter A., Frosch M.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WUE 2594.

Entry informationi

Entry nameiE7BGW8_NEIMW
AccessioniPrimary (citable) accession number: E7BGW8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 9, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi