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E7AYX5

- E7AYX5_YERE1

UniProt

E7AYX5 - E7AYX5_YERE1

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Protein
Alanine racemase
Gene
Y11_27531
Organism
Yersinia enterocolitica subsp. palearctica serotype O:3 (strain DSM 13030 / CIP 106945 / Y11)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei34 – 341Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei129 – 1291Substrate By similarityUniRule annotation
Active sitei254 – 2541Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei302 – 3021Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciYENT930944:GLMU-2793-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Y11_27531Imported
OrganismiYersinia enterocolitica subsp. palearctica serotype O:3 (strain DSM 13030 / CIP 106945 / Y11)Imported
Taxonomic identifieri930944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000008084: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei34 – 341N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE7AYX5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E7AYX5-1 [UniParc]FASTAAdd to Basket

« Hide

MKAATAVIDR RALRHNLQQV RRIAPQSRLI AVVKANAYGH GLLETAHTLQ    50
DADCYGVARI GEALMLRSGG IVKPILLLEG FFAAEDLPIL AANCIETAVH 100
SIEQLEALEV AELSAPIHVW MKLDTGMHRL GVRPEQAEAF YQRLSACKNV 150
IQPVNIMSHF SRADEPQVDT TRQQLDCFDT FAADKPGKQS IAASGGILLW 200
PEAHRDWVRP GIILYGVSPM DEPYASHFEL KPAMALKSSL IAVREHKAGE 250
PVGYGGTWVS ERDTRLGVVA IGYGDGYPRS APSGTPMWLN DREVGIVGRV 300
SMDMISVDLG PNATDKVGDE VLLWGAELPV EKIAACTGIS AYELITKLTS 350
RVAMEYLGE 359
Length:359
Mass (Da):39,120
Last modified:March 8, 2011 - v1
Checksum:i8486883D86AAF24F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FR729477 Genomic DNA. Translation: CBY25428.1.
RefSeqiYP_006006252.1. NC_017564.1.

Genome annotation databases

EnsemblBacteriaiCBY25428; CBY25428; Y11_27531.
GeneIDi12601430.
KEGGiyey:Y11_27531.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FR729477 Genomic DNA. Translation: CBY25428.1 .
RefSeqi YP_006006252.1. NC_017564.1.

3D structure databases

ProteinModelPortali E7AYX5.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBY25428 ; CBY25428 ; Y11_27531 .
GeneIDi 12601430.
KEGGi yey:Y11_27531.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci YENT930944:GLMU-2793-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete genome sequence of Y. enterocolitica subsp. palearctica serogroup O:3."
    Batzilla J., Hoeper D., Heesemann J., Rakin A.
    Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Y11.
  2. "Complete genome sequence of Yersinia enterocolitica subsp. palearctica serogroup O:3."
    Batzilla J., Hoper D., Antonenka U., Heesemann J., Rakin A.
    J. Bacteriol. 193:2067-2067(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13030 / CIP 106945 / Y11.

Entry informationi

Entry nameiE7AYX5_YERE1
AccessioniPrimary (citable) accession number: E7AYX5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 9, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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