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E7ABM7

- E7ABM7_HELFC

UniProt

E7ABM7 - E7ABM7_HELFC

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Protein

Glutamate decarboxylase

Gene

HFELIS_16480

Organism
Helicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciHFEL936155:GHMC-1614-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:HFELIS_16480Imported
OrganismiHelicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1)Imported
Taxonomic identifieri936155 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000007934: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.
OMAiPTFQINF.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

E7ABM7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLHTKSHIQR DNEKFVFKAD NSSTPIFGSA ESDVLLPRDK IGKNMMDPRI
60 70 80 90 100
AYQLVSDEMM HDGNPRYNLC TFVQTYMEEE ARKIMLDSMA TNAIDKSEYP
110 120 130 140 150
QTTEIEKRCV NIIANLWNAN HAEDFMGTST VGSSEACMLG GMAMKFRWRK
160 170 180 190 200
RAQALGIDIS KQKPNLIVSS GYQVVWEKFC VYWDVELREV PMSDFNNLTL
210 220 230 240 250
DPKEAIKLCD DYTIGIVPIM GITYTGGFDD IVTLDRLLSE YNQKAKISVS
260 270 280 290 300
IHVDAASGGL YLPFINPDLT WDFRLKNVVS ISTSGHKYGL IYPGIGWVMW
310 320 330 340 350
RDKQFLPDEL IFKVAYLGDF EPTFQINFSR SGSQIWAQYY CFVRWGFEGY
360 370 380 390 400
KAVHAKTRDV GLFLARGIKS LGLFDMINEG QNIPIICWTM NTKAQKEKQW
410 420 430 440 450
NLYDLADRLR FNGWQVPAYP LPANFQNVSV MRIVVRADQS MEQMSLFLKD
460 470 480
LKQAIRELDT ANLVSHKHPS ESDDVVPVGY TH
Length:482
Mass (Da):55,152
Last modified:March 8, 2011 - v1
Checksum:i9377F6EB9FEA1E12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ670179 Genomic DNA. Translation: CBY83732.1.
RefSeqiYP_004074322.1. NC_014810.2.

Genome annotation databases

EnsemblBacteriaiCBY83732; CBY83732; HFELIS_16480.
GeneIDi10050817.
KEGGihfe:HFELIS_16480.
PATRICi45241286. VBIHelFel178703_1714.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ670179 Genomic DNA. Translation: CBY83732.1 .
RefSeqi YP_004074322.1. NC_014810.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBY83732 ; CBY83732 ; HFELIS_16480 .
GeneIDi 10050817.
KEGGi hfe:HFELIS_16480.
PATRICi 45241286. VBIHelFel178703_1714.

Phylogenomic databases

HOGENOMi HOG000070228.
KOi K01580.
OMAi PTFQINF.

Enzyme and pathway databases

BioCyci HFEL936155:GHMC-1614-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Comparative whole genome analysis of the carcinogenic bacterial pathogen Helicobacter felis."
    Arnold A., Zigova Z., Lawley T., Falkow S., Bentley S., Aslett M., Muller A.
    Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49179 / NCTC 12436 / CS1Imported.

Entry informationi

Entry nameiE7ABM7_HELFC
AccessioniPrimary (citable) accession number: E7ABM7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: November 26, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3