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E7ABM7

- E7ABM7_HELFC

UniProt

E7ABM7 - E7ABM7_HELFC

Protein

Glutamate decarboxylase

Gene

HFELIS_16480

Organism
Helicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (08 Mar 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciHFEL936155:GHMC-1614-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Ordered Locus Names:HFELIS_16480Imported
    OrganismiHelicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1)Imported
    Taxonomic identifieri936155 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000007934: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000070228.
    KOiK01580.
    OMAiPTFQINF.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E7ABM7-1 [UniParc]FASTAAdd to Basket

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    MLHTKSHIQR DNEKFVFKAD NSSTPIFGSA ESDVLLPRDK IGKNMMDPRI    50
    AYQLVSDEMM HDGNPRYNLC TFVQTYMEEE ARKIMLDSMA TNAIDKSEYP 100
    QTTEIEKRCV NIIANLWNAN HAEDFMGTST VGSSEACMLG GMAMKFRWRK 150
    RAQALGIDIS KQKPNLIVSS GYQVVWEKFC VYWDVELREV PMSDFNNLTL 200
    DPKEAIKLCD DYTIGIVPIM GITYTGGFDD IVTLDRLLSE YNQKAKISVS 250
    IHVDAASGGL YLPFINPDLT WDFRLKNVVS ISTSGHKYGL IYPGIGWVMW 300
    RDKQFLPDEL IFKVAYLGDF EPTFQINFSR SGSQIWAQYY CFVRWGFEGY 350
    KAVHAKTRDV GLFLARGIKS LGLFDMINEG QNIPIICWTM NTKAQKEKQW 400
    NLYDLADRLR FNGWQVPAYP LPANFQNVSV MRIVVRADQS MEQMSLFLKD 450
    LKQAIRELDT ANLVSHKHPS ESDDVVPVGY TH 482
    Length:482
    Mass (Da):55,152
    Last modified:March 8, 2011 - v1
    Checksum:i9377F6EB9FEA1E12
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ670179 Genomic DNA. Translation: CBY83732.1.
    RefSeqiYP_004074322.1. NC_014810.2.

    Genome annotation databases

    EnsemblBacteriaiCBY83732; CBY83732; HFELIS_16480.
    GeneIDi10050817.
    KEGGihfe:HFELIS_16480.
    PATRICi45241286. VBIHelFel178703_1714.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ670179 Genomic DNA. Translation: CBY83732.1 .
    RefSeqi YP_004074322.1. NC_014810.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBY83732 ; CBY83732 ; HFELIS_16480 .
    GeneIDi 10050817.
    KEGGi hfe:HFELIS_16480.
    PATRICi 45241286. VBIHelFel178703_1714.

    Phylogenomic databases

    HOGENOMi HOG000070228.
    KOi K01580.
    OMAi PTFQINF.

    Enzyme and pathway databases

    BioCyci HFEL936155:GHMC-1614-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Comparative whole genome analysis of the carcinogenic bacterial pathogen Helicobacter felis."
      Arnold A., Zigova Z., Lawley T., Falkow S., Bentley S., Aslett M., Muller A.
      Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 49179 / NCTC 12436 / CS1Imported.

    Entry informationi

    Entry nameiE7ABM7_HELFC
    AccessioniPrimary (citable) accession number: E7ABM7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3