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Protein

ATP-dependent RNA helicase DeaD

Gene

deaD

Organism
Haemophilus influenzae F3031
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotationImported, Hydrolase, RNA-bindingUniRule annotation
Biological processStress responseUniRule annotation
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHINF866630:G1GVS-179-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent RNA helicase DeaDUniRule annotation (EC:3.6.4.13UniRule annotation)
Alternative name(s):
Cold-shock DEAD box protein AUniRule annotation
Gene namesi
Name:deaDUniRule annotation
ORF Names:HIBPF_01750Imported
OrganismiHaemophilus influenzae F3031Imported
Taxonomic identifieri866630 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000006795 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 33Q_MOTIFInterPro annotationAdd BLAST29
Domaini36 – 207Helicase ATP-bindingInterPro annotationAdd BLAST172
Domaini231 – 378Helicase C-terminalInterPro annotationAdd BLAST148

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi5 – 33Q motifPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family. DeaD subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000268810
KOiK05592

Family and domain databases

CDDicd00079 HELICc, 1 hit
cd12499 RRM_EcCsdA_like, 1 hit
Gene3Di3.30.70.3301 hit
HAMAPiMF_00964 DEAD_helicase_DeaD, 1 hit
InterProiView protein in InterPro
IPR034415 CsdA_RRM
IPR005580 DbpA/CsdA_RNA-bd_dom
IPR011545 DEAD/DEAH_box_helicase_dom
IPR028618 DEAD_helicase_DeaD
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
PfamiView protein in Pfam
PF03880 DbpA, 1 hit
PF00270 DEAD, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit

Sequencei

Sequence statusi: Complete.

E7A839-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDKITFNDL GLPEFILKAV SDLGFETPSP IQQSCIPHLL SGNDVLGMAQ
60 70 80 90 100
TGSGKTAAFA LPLLAQIDPS EKHPQMLVMA PTRELAIQVA DACELFVKYA
110 120 130 140 150
QGTRIVTLYG GQRYDIQLRA LKQGAQVVVG TPGRILDHIR RGTLNLSELR
160 170 180 190 200
FIVLDEADEM LRMGFIDDVE TVMAELPENH QTALFSATMP EPIRRITKRF
210 220 230 240 250
MNDPQEVKIK VNNENAPDID QSCWYVHGVR KNEALLRFLE VEDFDAAIIF
260 270 280 290 300
ARTKTGTLDI TELLEKNGFR SAALNGDMTQ QLREQTLDRL RNRSLDIVVA
310 320 330 340 350
TDVAARGIDI ERISLVVNYD IPLDAESYVH RIGRTGRAGR SGRALLFVEP
360 370 380 390 400
RERRLLRNIE HLMKKGINEV ELPNHEVLQE CRRKKFVAKI TKQLEHHDLE
410 420 430 440 450
QYRSLLEDLF TADQDQENIA AAMLMLLQGK QKLILPPDPP MEKRRRERNE
460 470 480 490 500
RGDRRENPRS AERRGERKGY VNPQPMDLYR IEVGRADGVE VRHIVGAIAN
510 520 530 540 550
EGDINSRYIG HIKLYDDYTT VELPQGMPKE LLQQFGKTRV LNKQMQMSFL
560 570 580 590 600
GAVKSDNSRG SDDFNGKCKG RGGDFRGERG RERGNDNRGN RKFNEKSNRT
610
FSDKPRRDRR SSF
Length:613
Mass (Da):69,783
Last modified:March 8, 2011 - v1
Checksum:i0E5AF49F6776B87F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ670178 Genomic DNA Translation: CBY80420.1
RefSeqiWP_013525494.1, NC_014920.1

Genome annotation databases

KEGGihif:HIBPF_01750

Similar proteinsi

Entry informationi

Entry nameiE7A839_HAEIF
AccessioniPrimary (citable) accession number: E7A839
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: March 28, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported